Molbank, Volume 2006, Issue 2

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Synthesis of 5,5’-biindole was carried out by the Madelung indole reaction. Under strong basic conditions and high temperatures (350 ºC), N,N’-bis-formyl-o-tolidine underwent cyclization to produce high amounts of the dimeric indole. Full and unambig...

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The product 2 was prepared by the addition of benzylamine (C6H5CH2NH2) to 1 [1] according to the reported procedure [2].[...]

The product 2 was prepared by the addition of piperazine (C4H10N2) to 1 [1] according to the reported procedure [2].[...]

4-(4-(dimethylamino)phenyl)-5-acetyl-6-phenyl-3,4-dihydropyrimidin-2(1H)-thione was prepared from benzoxyacetone (1) (1.62 g, 10 mmol), N,N-dimethylaniline (2) (1.21 g, 10 mmol) and thiourea (3) (1.140 g, 15 mmol) in dichloromethane (15 mL) as solven...

As part of research programme directed to the synthesis of novel heterocyclic compounds pharmacologically interesting [1] via ring transformation of 1,2,4-triazine derivatives, we synthesized the title compounds 3 via two step process.[...]

As part of research programme directed to the synthesis of novel heterocyclic compounds pharmacologically interesting [1] via ring transformation of 1,2,4-triazine derivatives, we synthesized the title compounds 3 via two step process.[...]

In 1882, Hantzsch reported the first synthesis of dialkyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates from a refluxing mixture of an aldehyde, a β-ketoester, and aqueous ammonium hydroxide in ethanol.[...]

To a solution of hydrazonoyl bromide (5.70 g, 0.02 mol) 2 and 1 [1] (3.18 g, 0.01 mol) in tetrahydrofuran (60 ml) was added triethylamine (2.02 g, 0.02 mol in 10 ml of THF).[...]