Table of Contents
Int. J. Mol. Sci., Volume 20, Issue 8 (April-2 2019)
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Cover Story (view full-size image) The capsid assembly of giant viruses has been an intriguing mystery for almost three decades. We [...] Read more. The capsid assembly of giant viruses has been an intriguing mystery for almost three decades. We developed a novel multiscale computational approach to thoroughly investigate the binding interactions among viral capsid proteins, starting from the flat area of the virus surface. Our results illuminate the elegant role of electrostatic interactions in guiding the capsid assembly of giant viruses. The study lays a solid cornerstone for fully unraveling the mysterious process of giant virus assembly. View this paper