Table of Contents
Int. J. Mol. Sci., Volume 20, Issue 7 (April-1 2019)
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Cover Story (view full-size image) The olfactory system detects odors and allows organisms to interact with their environment and to [...] Read more. The olfactory system detects odors and allows organisms to interact with their environment and to mediate behaviors for survival. Olfactory organs are particularly vulnerable to damage by pollutants, and toxicants since they are directly exposed to the environment. Given the widespread occurrence of environmental olfactory toxicants, there is a pressing need to understand the effects of these harmful compounds on olfactory function. Zebrafish (Danio rerio) is a valuable model for studying the olfactory system as its anatomical, morphological and functional organization are similar to other vertebrates. Zebrafish olfactory system presents remarkable regeneration, making it a significant model for studying olfactory dysfunction and regeneration. We describe the zebrafish olfactory system and review the effects of olfactory toxicants and injury as well as repair mechanisms following olfactory sensory damage. View this paper.