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Special Issue "Leptin and Relatives: Molecules at the Crossroad of Inflammation and Immunometabolism"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 July 2019).
Dr. Oreste Gualillo E-Mail
Servizo Galego de Saude and Institute of Biomedical Research (SERGAS-IDIS), The NEIRID LAB, Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases, 15706 Santiago University Clinical Hospital, Santiago de Compostela, Spain
Interests: leptin; adipokines; inflammation; arthritis; cartilage pathophysiology; immunometabolism; natural drugs
Next year, in 2019, we will celebrate the 25th anniversary of the discovery of leptin, the first member of the novel, recognized superfamily of molecules, collectively named adipokines. A quarter of a century, characterized by a plethora of studies that have led to the appreciation of the remarkable potency, range of biological effects and pleiotropism of leptin, as well as of many other adipokines. Leptin research in the last 25 years has significantly increased our understanding of the cellular and molecular mechanisms linking obesity and adipose tissue dysfunction to metabolic/immune/inflammatory disorders, a picture that is still incomplete. Research on leptin and relatives has permeated almost all biomedical disciplines, from endocrinology to rheumatology, just to simply cite a few. We invite authors to present original research articles, as well as review articles, that will stimulate the continue efforts in defining the molecular and cellular mechanisms of leptin and other adipokines in pathophysiology and clinics. Papers describing compelling mechanistic evidence linking the effects of leptin, and other adipokines, to the pathogenesis of immune–inflammatory–metabolic diseases are very welcome. Manuscripts reporting clinical applications of approved or investigational-adipokines research-based drugs with an emphasis on the cellular and molecular effects related to the efficacy, toxicity, response assessment, multimodality treatment, prognostic factors and predictive markers are also very welcome.
Dr. Oreste Gualillo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- metabolic diseases
- stress response