Table of Contents
Int. J. Mol. Sci., Volume 19, Issue 2 (February 2018) – 327 articles
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Cover Story (view full-size image) The IL-23/IL-17 axis mediates the initiation and persistence of inflammation during Psoriasis and [...] Read more. The IL-23/IL-17 axis mediates the initiation and persistence of inflammation during Psoriasis and Psoriatic Arthritis. IL-23 acts on numerous effector cells to drive the immune response in skin and joint disease either directly (IL-17-independent pathway) or indirectly by stimulating Th17 cells to release the inflammatory mediators IL-22 and IL-17 (IL-17-dependent pathway). View this paper