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7 Results Found

  • Case Report
  • Open Access
3 Citations
3,553 Views
12 Pages

Perforating dermatoses are dermatologic disorders with transepidermal elimination (TE) of dermal substances. While TE is typically associated with collagen and elastin, it can also occur as a secondary event in other processes, and it is important to...

  • Review
  • Open Access
1 Citations
2,315 Views
17 Pages

Dermoscopy of Acquired Perforating Dermatoses: A Case Series and Review of the Literature

  • Maria-Myrto Papadopoulou,
  • Emmanouil Karampinis,
  • Dimitrios Sgouros,
  • Styliani Sakellaropoulou,
  • Elizabeth Lazaridou,
  • Aimilios Lallas and
  • Zoe Apalla

21 November 2025

Acquired perforating dermatoses (APD) represent a group of papulonodular skin disorders characterized by transepidermal elimination of dermal components, most frequently arising in patients with poorly controlled chronic systemic conditions such as d...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
8 Citations
4,438 Views
16 Pages

20 December 2021

Background and objectives: The purpose of this study was to confirm the effect of Galgeunhwanggeumhwangryeon-tang (GGRT) on the skin barrier integrity and inflammation in an atopic dermatitis-like animal model. Materials and Methods: The model was es...

(This article belongs to the Section Hematology and Immunology)
  • Article
  • Open Access
6 Citations
4,206 Views
19 Pages

Stability Profile and Clinical Evaluation of an Innovative Hydrogel Containing Polymeric Micelles as Drug Delivery Systems with Oregano Essential Oil against Fibroepithelial Polyps

  • Larisa Bora,
  • Andrada Iftode,
  • Ana Maria Muț,
  • Lavinia Lia Vlaia,
  • Gheorghe-Emilian Olteanu,
  • Delia Muntean,
  • Cristina Adriana Dehelean,
  • Valentina Buda,
  • Georgeta Hermina Coneac and
  • Corina Danciu

Skin tags, also known as fibroepithelial polyps (FPs) or acrochordons, are soft, pigmented excrescences, with a prevalence of 50–60% in the population, occurring especially in the fourth decade of life. To date, FPs have been efficiently elimin...

(This article belongs to the Special Issue Hydrogels for Pharmaceutical and Biomedical Applications)
  • Systematic Review
  • Open Access
7 Citations
3,928 Views
13 Pages

Acquired Reactive Perforating Collagenosis—A Rare Entity Occurring Within Common Disorders: A Systematic Review and Our Personal Experience

  • Maria Alexandra Junghetu,
  • Cristina Violeta Tutunaru,
  • Simona Laura Ianoși,
  • Claudia Valentina Georgescu and
  • Olguța Anca Orzan

5 January 2026

Background/Objectives: Acquired reactive perforating collagenosis (ARPC) is a rare entity usually occurring in adults with systemic diseases such as diabetes mellitus, chronic kidney disease (CKD), cardiovascular diseases, and malignancies, although...

(This article belongs to the Section Dermatology)
  • Article
  • Open Access
38 Citations
8,274 Views
21 Pages

Efficacy of Pre- and Post-Treatment by Topical Formulations Containing Dissolved and Suspended Silybum marianum against UVB-Induced Oxidative Stress in Guinea Pig and on HaCaT Keratinocytes

  • Pálma Fehér,
  • Zoltán Ujhelyi,
  • Judit Váradi,
  • Ferenc Fenyvesi,
  • Eszter Róka,
  • Béla Juhász,
  • Balázs Varga,
  • Mariann Bombicz,
  • Dániel Priksz and
  • Miklós Vecsernyés
  • + 1 author

22 September 2016

Plants with high amounts of antioxidants may be a promising therapy for preventing and curing UV-induced oxidative skin damage. The objective of this study was to verify the efficacy of topical formulations containing dissolved and suspended Silybum ...

(This article belongs to the Section Natural Products Chemistry)
  • Systematic Review
  • Open Access
1 Citations
1,614 Views
17 Pages

Histopathological Changes Following Bromelain-Based Enzymatic Debridement (NexoBrid®): A Comprehensive Systematic Review of Preclinical and Clinical Evidence

  • Stefana Avadanei-Luca,
  • Dan-Cristian Moraru,
  • Andra-Irina Bulgaru-Iliescu,
  • Raluca Tatar,
  • Iulia Nacea,
  • Alexandru Hristo Amarandei,
  • Mihai-Codrin Constantinescu and
  • Mihaela Pertea

23 March 2026

Background: NexoBrid® (NXB; MediWound Ltd., Yavne, Israel) (anacaulase-bcdb) is a bromelain-based enzymatic debriding agent approved for eschar removal in burn care. Despite widespread clinical use, histological evidence of tissue-level changes a...