You are currently on the new version of our website. Access the old version .

15 Results Found

  • Review
  • Open Access
174 Citations
85,824 Views
33 Pages

The Therapeutic Potential of Psilocybin

  • Henry Lowe,
  • Ngeh Toyang,
  • Blair Steele,
  • Henkel Valentine,
  • Justin Grant,
  • Amza Ali,
  • Wilfred Ngwa and
  • Lorenzo Gordon

The psychedelic effects of some plants and fungi have been known and deliberately exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal source of naturally occurring psychedelics. The mushroom extract, psilocybi...

  • Review
  • Open Access
13 Citations
20,815 Views
16 Pages

Novel Perspective of Medicinal Mushroom Cultivations: A Review Case for ‘Magic’ Mushrooms

  • Sarana Rose Sommano,
  • Ratchuporn Suksathan,
  • Thanarat Sombat,
  • Pimjai Seehanam,
  • Sasithorn Sirilun,
  • Warintorn Ruksiriwanich,
  • Sutee Wangtueai and
  • Noppol Leksawasdi

15 December 2022

Fruiting bodies, mycelia, or spores in the form of extracts or powder of various medicinal mushrooms are used to prevent, treat, or cure a range of ailments and balance a healthy diet. Medicinal mushrooms are found in several genera of fungi and thei...

  • Review
  • Open Access
22 Citations
15,652 Views
12 Pages

7 February 2022

Psychedelics extracted from plants have been used in religious, spiritual, and mystic practices for millennia. In 1957, Dr. Hofmann identified and synthesized the prodrug psilocybin, a substance present in more than 200 species of psychedelic mushroo...

  • Article
  • Open Access
1,208 Views
30 Pages

29 October 2025

In his book The Sacred Mushroom and the Cross (1970), John Marco Allegro claimed that an obscure, 12th century CE fresco of the Fall of Adam and Eve in the Plaincourault Chapel in Mérigny, France, provided evidence of the persistence in Christ...

  • Review
  • Open Access
8 Citations
8,576 Views
18 Pages

A Review of Synthetic Access to Therapeutic Compounds Extracted from Psilocybe

  • Raphaël Serreau,
  • Ammar Amirouche,
  • Amine Benyamina and
  • Sabine Berteina-Raboin

28 December 2022

Psychedelics are used for various pathologies of the central nervous system and are currently the subject of much research, some of which relates to the compounds contained in various Psilocybe-type hallucinogenic mushrooms. It is difficult, however,...

  • Article
  • Open Access
1 Citations
3,383 Views
16 Pages

22 July 2025

This article examines the scholarship of John Allegro on the Dead Sea Scrolls and the role his status as a scholar has played in the reception of his The Sacred Mushroom and the Cross. While the Dead Sea Scrolls play no prominent role in the book, pe...

  • Review
  • Open Access
3,842 Views
21 Pages

Psychedelic plants and fungi have been traditionally used in many cultures as part of ritual ceremonies and ancient medicinal treatments. In some regions, these psychoactive plants have already entered mainstream discourse through popular literature...

  • Review
  • Open Access
12 Citations
13,871 Views
25 Pages

New Paradigms of Old Psychedelics in Schizophrenia

  • Danish Mahmood,
  • Sattam K. Alenezi,
  • Md. Jamir Anwar,
  • Faizul Azam,
  • Kamal A. Qureshi and
  • Mariusz Jaremko

Psychedelics such as lysergic acid diethylamide (LSD), psilocybin (magic mushrooms), and mescaline exhibit intense effects on the human brain and behaviour. In recent years, there has been a surge in studies investigating these drugs because clinical...

  • Review
  • Open Access
17 Citations
12,933 Views
19 Pages

11 March 2022

Mushrooms have been used as traditional medicine for millennia, fungi are the main natural source of psychedelic compounds. There is now increasing interest in using fungal active compounds such as psychedelics for alleviating symptoms of mental heal...

  • Article
  • Open Access
37 Citations
33,836 Views
16 Pages

Extensive Collection of Psychotropic Mushrooms with Determination of Their Tryptamine Alkaloids

  • Klára Gotvaldová,
  • Jan Borovička,
  • Kateřina Hájková,
  • Petra Cihlářová,
  • Alan Rockefeller and
  • Martin Kuchař

15 November 2022

Since not only psilocybin (PSB) but also PSB-containing mushrooms are used for psychedelic therapy and microdosing, it is necessary to know their concentration variability in wild-grown mushrooms. This article aimed to determine the PSB, psilocin (PS...

  • Article
  • Open Access
3,761 Views
25 Pages

Mycelium Growth and Development of Psilocybe spp. Mother Cultures on Agar-Based Media

  • Marco Pepe,
  • Mohsen Hesami,
  • Livia Fleishmann,
  • Tom Hsiang and
  • Andrew Maxwell Phineas Jones

13 June 2025

The resurgence of interest in the therapeutic potential of psilocybin-producing mushrooms has recently led to numerous research and commercialization efforts. Due to its ease of cultivation and high potency, Psilocybe is the primary genus of interest...

  • Article
  • Open Access
20 Citations
11,917 Views
12 Pages

Rostral Anterior Cingulate Thickness Predicts the Emotional Psilocybin Experience

  • Candace R. Lewis,
  • Katrin H. Preller,
  • B. Blair Braden,
  • Cory Riecken and
  • Franz X. Vollenweider

Psilocybin is the psychoactive compound of mushrooms in the psilocybe species. Psilocybin directly affects a number of serotonin receptors, with highest affinity for the serotonin 2A receptor (5HT-2Ar). Generally, the effects of psilocybin, and its a...

  • Protocol
  • Open Access
2 Citations
4,691 Views
7 Pages

28 November 2021

Fungi are embedded in human culture, tradition, and art, and have featured as inspirational and visual motifs. Psychedelic and medicinal mushrooms have been sculpted, painted, and ingested by our ancestors since prehistory. In modern times, the growi...

  • Review
  • Open Access
2 Citations
68,021 Views
24 Pages

Exploring Psilocybe cubensis Strains: Cultivation Techniques, Psychoactive Compounds, Genetics and Research Gaps

  • Eyal Kurzbaum,
  • Tomáš Páleníček,
  • Amiel Shrchaton,
  • Sara Azerrad and
  • Yaron Dekel

28 January 2025

Psilocybe cubensis, a widely recognized psychoactive mushroom species, has played a significant role in both historical and modern therapeutic practices. This review explores the complex interplay between genetic diversity, strain variability and env...