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6 Results Found

  • Review
  • Open Access
19 Citations
5,557 Views
14 Pages

Placental Mesenchymal Dysplasia and Beckwith–Wiedemann Syndrome

  • Hidenobu Soejima,
  • Satoshi Hara,
  • Takashi Ohba and
  • Ken Higashimoto

12 November 2022

Placental mesenchymal dysplasia (PMD) is characterized by placentomegaly, aneurysmally dilated chorionic plate vessels, thrombosis of the dilated vessels, and large grapelike vesicles, and is often mistaken for partial or complete hydatidiform mole w...

(This article belongs to the Special Issue Beckwith–Wiedemann Spectrum and Cancer)
  • Case Report
  • Open Access
7,422 Views
13 Pages

Prenatal Diagnosis of Placental Mesenchymal Dysplasia with 46, X, Isochromosome Xq/45, X Mosaicism

  • Chin-Chieh Hsu,
  • Chien-Hong Lee,
  • Shuenn-Dyh Chang,
  • Tsang-Ming Ko,
  • Shir-Hwa Ueng,
  • Yu-Hsiu Chen,
  • Mei-Chia Wang and
  • Yao-Lung Chang

27 January 2022

Placental mesenchymal dysplasia is an uncommon vascular anomaly of the placenta with characteristics of placentomegaly and multicystic appearance and with or without association with fetal chromosomal anomaly. We present a unique placental mesenchyma...

(This article belongs to the Section Genetic Diagnosis)
  • Review
  • Open Access
15 Citations
8,998 Views
19 Pages

A Challenging Diagnosis: Placental Mesenchymal Dysplasia—Literature Review and Case Report

  • Claudia Mehedintu,
  • Francesca Frincu,
  • Oana-Maria Ionescu,
  • Monica Mihaela Cirstoiu,
  • Maria Sajin,
  • Maria Olinca,
  • Elvira Bratila,
  • Aida Petca and
  • Andreea Carp-Veliscu

We describe a 22-year-old woman (2-gravid) case who was referred to our clinic at 18 weeks of gestation for a placenta with vesicular lesions discovered on prenatal examination routine. An ultrasound exam at 31 weeks of gestation showed numerous vesi...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
8 Citations
3,878 Views
17 Pages

Variants in Maternal Effect Genes and Relaxed Imprinting Control in a Special Placental Mesenchymal Dysplasia Case with Mild Trophoblast Hyperplasia

  • Tien-Chi Huang,
  • Kung-Chao Chang,
  • Jen-Yun Chang,
  • Yi-Shan Tsai,
  • Yao-Jong Yang,
  • Wei-Chun Chang,
  • Chu-Fan Mo,
  • Pei-Hsiu Yu,
  • Chun-Ting Chiang and
  • Pao-Lin Kuo
  • + 1 author

Placental mesenchymal dysplasia (PMD) and partial hydatidiform mole (PHM) placentas share similar characteristics, such as placental overgrowth and grape-like placental tissues. Distinguishing PMD from PHM is critical because the former can result in...

(This article belongs to the Special Issue Gynecological Tumor and Placenta Development)
  • Article
  • Open Access
4 Citations
4,039 Views
17 Pages

A Preconception Paternal Fish Oil Diet Prevents Toxicant-Driven New Bronchopulmonary Dysplasia in Neonatal Mice

  • Jelonia T. Rumph,
  • Kayla J. Rayford,
  • Victoria R. Stephens,
  • Sharareh Ameli,
  • Pius N. Nde,
  • Kevin G. Osteen and
  • Kaylon L. Bruner-Tran

27 December 2021

New bronchopulmonary dysplasia is a developmental lung disease associated with placental dysfunction and impaired alveolarization. Risk factors for new BPD include prematurity, delayed postnatal growth, the dysregulation of epithelial-to-mesenchymal...

(This article belongs to the Special Issue Developmental Exposure to Environmental Contaminants)
  • Case Report
  • Open Access
1 Citations
1,631 Views
12 Pages

Biparental and Androgenetic Somatic Mosaicism with Presentation of Non-Syndromic Severe Neonatal Hyperinsulinemia

  • Miguel Angel Alcántara-Ortigoza,
  • Marcela Vela-Amieva,
  • Ariadna González-del Angel,
  • Miriam Erandi Reyna-Fabián,
  • Liliana Fernández-Hernández,
  • Bernardette Estandía-Ortega,
  • Sara Guillén-López,
  • Lizbeth López-Mejía,
  • Isabel Ibarra-González and
  • Cynthia Fernández-Lainez
  • + 6 authors

19 August 2025

Genome-wide paternal uniparental isodisomy mosaicism (GWpUPIDM) is an extremely rare condition characterized by varying proportions of an androgenetic cell line across different tissues. It is primarily associated with severe congenital hyperinsulini...

(This article belongs to the Special Issue Exploring Rare Diseases: Genetic, Genomic and Metabolomic Advances: 2nd Edition)