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25 Results Found

  • Article
  • Open Access
9 Citations
5,908 Views
24 Pages

Data-Driven Methodology for Coliving Spaces and Space Profiling Based on Post-Occupancy Evaluation through Digital Trail of Users

  • Alicia Regodon,
  • Maxime Armand,
  • Carmen Lastres,
  • Jose De Pedro and
  • Alfonso García-Santos

15 November 2021

Sustainable spaces are those that are optimized, accessible, promote user experience and aim to reduce CO2 emissions while enhancing users’ well-being and comfort. The purpose of this paper is to present a methodology that was developed during the CO...

  • Article
  • Open Access
5 Citations
5,303 Views
21 Pages

Kindness in Architecture: The Multispecies Co-Living and Co-Design

  • Sareh Saeidi,
  • Matthew Dylan Anderson and
  • Marie Davidová

The research’s main objective is to explore and encourage modes of architectural practice that can foster multispecies co-living to reduce biodiversity loss and increase the quality of life for both human and nonhuman inhabitants of architecture. Thi...

  • Article
  • Open Access
3 Citations
6,202 Views
15 Pages

12 October 2023

Co-living is commonly considered as an arrangement for rental housing. However, co-living in housing estates by sharing common amenities among co-owners has been practiced for many years in high-density cities. Yet, there have been very few empirical...

  • Article
  • Open Access
7 Citations
5,252 Views
27 Pages

26 January 2024

In contemporary society, a notable trend of diminishing family sizes has led to an increasing number of elderly individuals living in solitude, often facing the end of life alone. This phenomenon underscores a critical challenge: addressing the perva...

  • Article
  • Open Access
6 Citations
3,621 Views
36 Pages

13 October 2021

This article seeks the qualitative synthesis of schools of thought from extreme climate regions that could support urban biodiversity and climate change adaptation through architectural design. It proposes that climate comfort and biodiversity are cl...

  • Article
  • Open Access
29 Citations
3,250 Views
10 Pages

Association of Co-Living and Age on the Type of Sports Practiced by Older People

  • María Antonia Parra-Rizo,
  • Felipe Díaz-Toro,
  • Fatine Hadrya,
  • Patricia Pavón-León and
  • Igor Cigarroa

5 December 2022

Introdution: The environment and the type of co-living of older people are crucial to understanding how the nature of their context influences a healthy lifestyle. However, no studies have investigated to what extent their type of co-living may be as...

  • Article
  • Open Access
1 Citations
2,501 Views
16 Pages

Architectural design and urban renewal that adapt to an ageing society and are localized are urgent needs around the world. On the other hand, the concept of grey space, which refers to transitional space and is an in-between concept, has been propos...

  • Article
  • Open Access
1 Citations
1,153 Views
18 Pages

Oxidative Stress Mediates the Dual Regulatory Effects of Bovine Uterine ECM Remodeling Through the TGF-β1/Smad3 Pathway: Molecular Mechanisms of MMPs and COL-IV Imbalances

  • Jiamei Tan,
  • Zongjie Wang,
  • Mingmao Yang,
  • Ruihang Zhang,
  • Zhongqiang Xue,
  • Dong Zhou,
  • Aihua Wang,
  • Pengfei Lin and
  • Yaping Jin

23 June 2025

Bovine endometritis is a common endocrine and reproductive disorder in postpartum dairy cows, closely associated with elevated systemic oxidative stress. This disease can lead to delayed uterine involution, repeated breeding failure, and significant...

  • Article
  • Open Access
13 Citations
3,994 Views
20 Pages

Type IV Collagen and SOX9 Are Molecular Targets of BET Inhibition in Experimental Glomerulosclerosis

  • José Luis Morgado-Pascual,
  • Beatriz Suarez-Alvarez,
  • Vanessa Marchant,
  • Pamela Basantes,
  • Pierre-Louis Tharaux,
  • Alberto Ortiz,
  • Carlos Lopez-Larrea,
  • Marta Ruiz-Ortega and
  • Sandra Rayego-Mateos

28 December 2022

Progressive glomerulonephritis (GN) is characterized by an excessive accumulation of extracellular (ECM) proteins, mainly type IV collagen (COLIV), in the glomerulus leading to glomerulosclerosis. The current therapeutic approach to GN is suboptimal....

  • Article
  • Open Access
11 Citations
6,248 Views
18 Pages

6 August 2012

Prohibitin (PHB) and paired box 2 (PAX2) are associated with the development of renal interstitial fibrosis (RIF). This study was performed to investigate whether or not the PHB could regulate the PAX2 gene expression in unilateral ureteral obstructi...

  • Article
  • Open Access
16 Citations
5,345 Views
13 Pages

31 October 2012

The nuclear retinoic acid receptors (RARs) function as ligand-dependent transcriptional regulators and include three subtypes (RARα, RARβ and RARγ), which control the expression of specific gene subsets subsequent to ligand binding and to strictly co...

  • Article
  • Open Access
47 Citations
7,533 Views
12 Pages

Sesamin Ameliorates High-Fat Diet–Induced Dyslipidemia and Kidney Injury by Reducing Oxidative Stress

  • Ruijuan Zhang,
  • Yan Yu,
  • Jianjun Deng,
  • Chao Zhang,
  • Jinghua Zhang,
  • Yue Cheng,
  • Xiaoqin Luo,
  • Bei Han and
  • Haixia Yang

9 May 2016

The study explored the protective effect of sesamin against lipid-induced renal injury and hyperlipidemia in a rat model. An animal model of hyperlipidemia was established in Sprague-Dawley rats. Fifty-five adult Sprague-Dawley rats were divided into...

  • Article
  • Open Access
34 Citations
7,514 Views
14 Pages

All-Trans Retinoic Acid Treatment Is Associated with Prohibitin Expression in Renal Interstitial Fibrosis Rats

  • Tian-Biao Zhou,
  • Yuan-Han Qin,
  • Zheng-Yi Li,
  • Hui-Ling Xu,
  • Yan-Jun Zhao and
  • Feng-Ying Lei

1 March 2012

This study was performed to investigate the association of prohibitin with renal interstitial fibrosis (RIF) lesion and to explore the association of all-trans retinoic acid (ATRA) treatment with prohibitin expression in RIF rats. Rats were divided i...

  • Article
  • Open Access
14 Citations
5,110 Views
13 Pages

“Vaccinate, Do Not Hesitate!”. Vaccination Readiness against COVID-19 among Polish Nursing Undergraduate Students: A National Cross-Sectional Survey

  • Joanna Gotlib,
  • Tomasz Sobierajski,
  • Mariusz Jaworski,
  • Dominik Wawrzuta,
  • Ewa Borowiak,
  • Beata Dobrowolska,
  • Danuta Dyk,
  • Aleksandra Gaworska-Krzemińska,
  • Elżbieta Grochans and
  • Mariusz Panczyk
  • + 6 authors

16 September 2021

COVID-19 vaccination raises numerous concerns among the public, and also among medical personnel including nurses. As nurses play a crucial role in the process of vaccination, it is important to recognize the attitudes of students of nursing, nurses...

  • Article
  • Open Access
6 Citations
3,365 Views
32 Pages

Evaluation of the Effect of an α-Adrenergic Blocker, a PPAR-γ Receptor Agonist, and a Glycemic Regulator on Chronic Kidney Disease in Diabetic Rats

  • Jorge Morones,
  • Mariana Pérez,
  • Martín Muñoz,
  • Esperanza Sánchez,
  • Manuel Ávila,
  • Jorge Topete,
  • Javier Ventura and
  • Sandra Martínez

23 October 2024

Diabetic nephropathy (DN) is a globally widespread complication of diabetes mellitus (DM). Research indicates that pioglitazone and linagliptin mitigate the risk of DN by reducing inflammation, oxidative stress, and fibrosis. The role of tamsulosin i...

  • Article
  • Open Access
4 Citations
2,376 Views
13 Pages

Dying during the COVID-19 Pandemic in Sweden: Relatives’ Experiences of End-of-Life Care (the CO-LIVE Study)

  • Christel Hedman,
  • Carl Johan Fürst,
  • Birgit H. Rasmussen,
  • Agnes van der Heide and
  • Maria E. C. Schelin

Background: The COVID-19 pandemic has seen many deaths, but the majority were for causes other than COVID-19. However, end-of-life care in all settings has been affected by measures limiting the spread of the virus, for patients with and without COVI...

  • Article
  • Open Access
1 Citations
1,235 Views
14 Pages

1 October 2025

In response to the growing relevance of shared housing models such as co-living and co-housing, this study investigates how spatial configuration affects the experience and negotiation of privacy in shared domestic environments. While privacy is ofte...

  • Article
  • Open Access
45 Citations
9,187 Views
13 Pages

Icariin Ameliorates Streptozotocin-Induced Diabetic Retinopathy in Vitro and in Vivo

  • Hua Xin,
  • Feng Zhou,
  • Tao Liu,
  • Guang-Yong Li,
  • Jing Liu,
  • Zhe-Zhu Gao,
  • Guang-Yi Bai,
  • Hong Lu and
  • Zhong-Cheng Xin

16 January 2012

This study investigated the effect of Icariin (ICA) supplementation on diabetic retinopathy (DR) in a streptozotocin-induced diabetic rat model system. Fifty Sprague Dawley rats were randomly distributed into a control group and a streptozotocin-indu...

  • Article
  • Open Access
1,207 Views
20 Pages

Microbiota Analysis and Characterisation of the Novel Limosilactobacillus Strains Isolated from Dogs

  • Ga-Yeong Lee,
  • Hae-Yeon Jo,
  • Muhammad Aleem Abbas,
  • Ling Gui,
  • Md Sekendar Ali,
  • Seung-Jun Kim and
  • Seung-Chun Park

Background/Objectives: The growing number of households with companion dogs raises concerns. Co-living environments between companion dogs and their owners are linked to a heightened risk of cross-infections from strains such as Escherichia coli (E. ...

  • Article
  • Open Access
13 Citations
6,100 Views
13 Pages

Pigeon haemoproteosis caused by Haemoproteus columbae (Apicomplexa: Haemosporida: Haemoproteidae) is globally prevalent in rock doves (Columba livia), although little is known regarding this disease in pigeons and doves in Indonesia. Blood samples of...

  • Article
  • Open Access
1,195 Views
22 Pages

27 September 2025

Background: Alpiniae oxyphyllae-Saposhnikovia divaricata (AS), a traditional Chinese dietary supplement, exhibits potential therapeutic effects against diabetic kidney disease (DKD), though its active compounds and mechanisms require elucidation. Met...

  • Article
  • Open Access
1 Citations
5,267 Views
14 Pages

This study investigated the perceived speaking skills of undergraduate students who were majoring or minoring in Japanese Studies at two universities in Vietnam and Bulgaria. It also examined the factors associated with students’ speaking skill...

  • Article
  • Open Access
16 Citations
4,427 Views
18 Pages

Destination Responses to COVID-19 Waves: Is “Green Zone” Initiative a Holy Grail for Tourism Recovery?

  • Da Van Huynh,
  • Long Hai Duong,
  • Thuy Thi Kim Truong and
  • Nhan Trong Nguyen

15 March 2022

Despite the stagnant status of the tourism industry due to the COVID-19 pandemic, the efforts to reopen the tourism destinations as green zones in Vietnam have paid off with some encouraging achievements. This inspires other green zones to consider a...

  • Article
  • Open Access
477 Citations
130,020 Views
15 Pages

23 March 2023

A new era of education and research based on chatbots and artificial intelligence is quickly growing. However, the application of these new systems is associated with several challenges and limitations, mainly related to ethics. This paper explores t...

  • Article
  • Open Access
2 Citations
2,577 Views
21 Pages

Investigations on the Health Status and Infection Risk of Harbour Seals (Phoca vitulina) from Waters of the Lower Saxon Wadden Sea, Germany

  • Ursula Siebert,
  • Jan Lakemeyer,
  • Martin Runge,
  • Peter Lienau,
  • Silke Braune,
  • Edda Bartelt,
  • Miguel L. Grilo and
  • Ralf Pund

10 October 2024

Harbour seals (Phoca vitulina) are the most common pinniped species in the Wadden Sea of Schleswig-Holstein, Hamburg and Lower Saxony, Germany. Their numbers have recovered after significant depletion due to viral outbreaks and effects of anthropogen...