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17 Results Found

  • Article
  • Open Access
19 Citations
7,247 Views
11 Pages

Prevalence of Diabetes and Associated Factors in the Uyghur and Han Population in Xinjiang, China

  • Haiying Gong,
  • Lize Pa,
  • Ke Wang,
  • Hebuli Mu,
  • Fen Dong,
  • Shengjiang Ya,
  • Guodong Xu,
  • Ning Tao,
  • Li Pan and
  • Guangliang Shan
  • + 1 author

Objective: To estimate the prevalence of diabetes and identify risk factors in the Uyghur and Han population in Xinjiang, China. Methods: A cross-sectional study in urban and rural areas in Xinjiang, including 2863 members of the Uyghur population an...

  • Article
  • Open Access
13 Citations
5,332 Views
12 Pages

Association between Polymorphisms and Haplotype in the ABCA1 Gene and Overweight/Obesity Patients in the Uyghur Population of China

  • Ming-Hong Yao,
  • Jia He,
  • Ru-Lin Ma,
  • Yu-Song Ding,
  • Heng Guo,
  • Yi-Zhong Yan,
  • Jing-Yu Zhang,
  • Jia-Ming Liu,
  • Mei Zhang and
  • Shu-Xia Guo
  • + 2 authors

Objective: This study aimed to detect the association between polymorphisms and haplotype in the ATP-binding cassette transporter A1 (ABCA1) gene and overweight/obese Uyghur patients in China. Methods: A total of 259 overweight/obese patients and 276...

  • Article
  • Open Access
22 Citations
3,878 Views
14 Pages

Metabolic Dysfunction-Associated Fatty Liver Disease Is Associated with the Risk of Incident Cardiovascular Disease: A Prospective Cohort Study in Xinjiang

  • Yanbo Guo,
  • Jing Yang,
  • Rulin Ma,
  • Xianghui Zhang,
  • Heng Guo,
  • Jia He,
  • Xinping Wang,
  • Boyu Cao,
  • Remina Maimaitijiang and
  • Shuxia Guo
  • + 3 authors

7 June 2022

In 2020, a group of international experts proposed a new term ‘metabolic dysfunction-associated fatty liver disease’ (MAFLD) to replace ‘non-alcoholic fatty liver disease’. This study aimed to describe the epidemic characteris...

  • Article
  • Open Access
20 Citations
5,306 Views
9 Pages

Prevalence of Hypertension among Adults in Remote Rural Areas of Xinjiang, China

  • Yulin Wang,
  • Jingyu Zhang,
  • Yusong Ding,
  • Mei Zhang,
  • Jiaming Liu,
  • Jiaolong Ma,
  • Heng Guo,
  • Yizhong Yan,
  • Jia He and
  • Shuxia Guo
  • + 4 authors

Objective: The present study aimed to estimate prevalence of hypertension among adults in rural remote areas of Xinjiang, China and evaluate the associated factors of hypertension. Methods: The survey was based on questionnaire interviews and clinica...

  • Article
  • Open Access
24 Citations
6,442 Views
13 Pages

Ethnic Differences in the Prevalence of High Homocysteine Levels Among Low-Income Rural Kazakh and Uyghur Adults in Far Western China and Its Implications for Preventive Public Health

  • Shuxia Guo,
  • Hongrui Pang,
  • Heng Guo,
  • Mei Zhang,
  • Jia He,
  • Yizhong Yan,
  • Qiang Niu,
  • Muratbek,
  • Dongsheng Rui and
  • Yusong Ding
  • + 4 authors

Objective: Homocysteine (Hcy) is a relevant biomarker of vascular disease: serum Hcy concentrations will increase the risk of systolic hypertension, whereas hyperhomocysteinemia (HHcy) has a synergistic effect with hypertension and increases the risk...

  • Article
  • Open Access
2 Citations
5,004 Views
15 Pages

24 July 2019

Given its generality in applications and its high time-efficiency on big data-sets, in recent years, the technique of text filtering through pattern matching has been attracting increasing attention from the field of information retrieval and Natural...

  • Article
  • Open Access
13 Citations
6,644 Views
12 Pages

Background: Metabolic syndrome is pandemic; however, the cut-off values for waist circumference (WC) vary widely depending on the ethnic groups studied and the criteria applied for WC measurement. Previous studies for defining optimal WC cut-off poin...

  • Article
  • Open Access
15 Citations
5,412 Views
14 Pages

We have investigated the relationship between the polymorphisms and haplotypes in the CETP gene, and dyslipidemia among the Xinjiang Kazak and Uyghur populations in China. A total of 712 patients with dyslipidemia and 764 control subjects of CETP gen...

  • Article
  • Open Access
10 Citations
15,326 Views
11 Pages

Ancient Components and Recent Expansion in the Eurasian Heartland: Insights into the Revised Phylogeny of Y-Chromosomes from Central Asia

  • Maxat Zhabagin,
  • Lan-Hai Wei,
  • Zhaxylyk Sabitov,
  • Peng-Cheng Ma,
  • Jin Sun,
  • Zhanargul Dyussenova,
  • Elena Balanovska,
  • Hui Li and
  • Yerlan Ramankulov

1 October 2022

In the past two decades, studies of Y chromosomal single nucleotide polymorphisms (Y-SNPs) and short tandem repeats (Y-STRs) have shed light on the demographic history of Central Asia, the heartland of Eurasia. However, complex patterns of migration...

  • Article
  • Open Access
6 Citations
2,805 Views
20 Pages

27 October 2024

Traditional villages are one of the basic types of rural revitalisation and one of the important carriers of cultural inheritance. This research is based on the data of 53 traditional villages in the Xinjiang Uyghur Autonomous Region with the aid of...

  • Article
  • Open Access
3 Citations
6,855 Views
25 Pages

Global Picture of Genetic Relatedness and the Evolution of Humankind

  • Gennady V. Khvorykh,
  • Oleh A. Mulyar,
  • Larisa Fedorova,
  • Andrey V. Khrunin,
  • Svetlana A. Limborska and
  • Alexei Fedorov

10 November 2020

We performed an exhaustive pairwise comparison of whole-genome sequences of 3120 individuals, representing 232 populations from all continents and seven prehistoric people including archaic and modern humans. In order to reveal an intricate picture o...

  • Article
  • Open Access
1 Citations
5,242 Views
14 Pages

Interethnic marriage amongst China’s ethnic population has not received the attention it deserves. This is partly due to the hesitation and resistance of the more prominent ethnic groups—Tibetans and Uyghurs—to enter an interethnic...

  • Article
  • Open Access
504 Views
16 Pages

Using Whole-Genome Sequencing Data Reveals the Population Structure and Selection Signatures for Reproduction Traits in Duolang Sheep

  • Keyao Wang,
  • Qianjun Li,
  • Zhigang Niu,
  • Zhengfen Xue,
  • Shiyuan Li,
  • Jiabao Yan,
  • Yang Chen,
  • Yanlong Zhang,
  • Hongcai Shi and
  • Xiangdong Ding

1 December 2025

Duolang sheep, a meat–fat dual-purpose breed indigenous to Xinjiang, China, has been cultivated traditionally by the local Uyghur people for its prolificacy and precocious sexual maturity, while little research on the population structure and t...

  • Article
  • Open Access
481 Views
21 Pages

29 November 2025

Background/Objectives: The functional architecture connecting speech production and reading comprehension remains unclear in multilinguals. This study investigated the cross-modal interaction between these systems in trilinguals to resolve the debate...

  • Article
  • Open Access
15 Citations
3,145 Views
12 Pages

Chemical Profiling of Kaliziri Injection and Quantification of Six Caffeoyl Quinic Acids in Beagle Plasma by LC-MS/MS

  • Changhua Liu,
  • Atikanmu Wahefu,
  • Xueying Lu,
  • Rahima Abdulla,
  • Jun Dou,
  • Haiqing Zhao,
  • Haji Akber Aisa,
  • Xuelei Xin and
  • Yongqiang Liu

Vitiligo is a stubborn multifactorial skin disease with a prevalence of approximately 1% in the global population. Kaliziri, the seeds of Vernonia anthelmintica (L.) Willd., is a well-known traditional Uyghur medicine for the treatment of vitiligo. K...

  • Article
  • Open Access
13 Citations
7,079 Views
18 Pages

12 January 2018

In arid regions, oases ecosystems are fragile and sensitive to climate change, and water is the major limiting factor for environmental and socio-economic developments. Understanding the drivers of land use/cover change (LUCC) in arid regions is impo...

  • Article
  • Open Access
14 Citations
5,224 Views
21 Pages

10 July 2022

As a large-scale irrigation and water conservancy project in ancient times, karez are common in Central Asia and arid regions with a history of thousands of years. Turpan, which is located in the Xinjiang Uyghur Autonomous Region, has the most extens...