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7 Results Found

  • Article
  • Open Access
14 Citations
4,245 Views
18 Pages

Interplay between Partial EMT and Cisplatin Resistance as the Drivers for Recurrence in HNSCC

  • Julia Ingruber,
  • Jozsef Dudas,
  • Susanne Sprung,
  • Bianca Lungu and
  • Felicitas Mungenast

This study aims to investigate the role of partial epithelial to mesenchymal transition (pEMT)-related proteins in modulating Cisplatin resistance in head and neck squamous cell carcinoma (HNSCC). SCC-25 cells were pre-treated with TGF-beta1 followed...

(This article belongs to the Special Issue Killing It Softly–New Approaches to Overcome Cancer Chemoresistance)
  • Article
  • Open Access
1,265 Views
16 Pages

Tissue Cytometry Assay with Nuclear Segmentation for Quantifying NETotic Cells in Neutrophils Stimulated by Spermatozoa in Veterinary Species

  • Rodrigo Rivera-Concha,
  • Marion León,
  • Nikol Ponce-Rojas,
  • Aurora Prado-Sanhueza and ,
  • Pamela Uribe,
  • Anja Taubert,
  • Carlos Hermosilla,
  • Raúl Sánchez and
  • Fabiola Zambrano
  • + 4 authors+ 0 author

19 September 2025

Upon activation, neutrophils perform three distinct functions: phagocytosis, degranulation of antimicrobial substances into the extracellular medium, and release of neutrophil extracellular traps. Determination of the nuclear area expansion of neutro...

(This article belongs to the Special Issue Molecular Mechanisms, Immunological, and Physiological Aspects Impacting Animal Fertility)
  • Article
  • Open Access
7 Citations
3,811 Views
9 Pages

The Prognostic and Predictive Value of SOX2+ Cell Densities in Patients Treated for Colorectal Cancer

  • Tim J. Miller,
  • Melanie J. McCoy,
  • Tracey F. Lee-Pullen,
  • Chidozie C. Anyaegbu and ,
  • Christine Hemmings,
  • Max K. Bulsara and
  • Cameron F. Platell
  • + 2 authors+ 0 author

29 April 2020

SOX2 (sex-determining region-Y homeobox-2) is a transcription factor essential for the maintenance of pluripotency and is also associated with stem-cell-like properties in preclinical cancer models. Our previous study on a cohort of stage III colon c...

(This article belongs to the Special Issue Gene Expression and Molecular Profiling of Human Cancer Stem Cells)
  • Article
  • Open Access
2 Citations
613 Views
16 Pages

Dynamics of Extracellular Traps in Vaginal Dysbiosis Associated with Gardnerella vaginalis: Ex Vivo Evidence from Neutrophils and Monocytes

  • Aurora Prado-Sanhueza,
  • Angélica Melo,
  • Isabel Iturrieta-González,
  • Pablo Navarro and
  • Fabiola Zambrano

Vaginal dysbiosis, particularly bacterial vaginosis (BV), is associated with altered immune responses that may influence the formation of extracellular traps (ETs). This study aimed to characterize neutrophil and macrophage extracellular traps (NETs...

(This article belongs to the Section Molecular Biology)
  • Systematic Review
  • Open Access
13 Citations
5,655 Views
13 Pages

Suicidal Ideation and Death by Suicide as a Result of the COVID-19 Pandemic in Spanish-Speaking Countries: Systematic Review

  • Nicolás Valle-Palomino,
  • Mirtha Mercedes Fernández-Mantilla,
  • Danae de Lourdes Talledo-Sebedón,
  • Olinda Victoria Guzmán-González and ,
  • Vanessa Haydee Carguachinchay-Huanca,
  • Alfonso Alejandro Sosa-Lizama,
  • Brunella Orlandini-Valle and
  • Óscar Manuel Vela-Miranda
  • + 3 authors+ 0 author

24 October 2023

Suicidal behaviors and constructs are putting at risk the accomplishment of Objective 3 of Agenda 2030 for sustainable development in Spanish-speaking countries. The current study’s principal objective is to explain the presence of suicidal ide...

(This article belongs to the Section Mental Health)
  • Article
  • Open Access
11 Citations
5,550 Views
12 Pages

Mosquito Communities Vary across Landscape and Vertical Strata in Indian River County, Florida

  • Bryan V. Giordano,
  • Anthony Cruz,
  • Daniel W. Pérez-Ramos,
  • Martina M. Ramos and ,
  • Yasmin Tavares and
  • Eric P. Caragata
  • + 1 author+ 0 author

3 December 2021

Mosquito and arbovirus surveillance is essential to the protection of public health. A majority of surveys are undertaken at ground level. However, mosquitoes shelter, breed, and quest for hosts across vertical strata, thus limiting our ability to fu...

(This article belongs to the Special Issue Epidemiology, Surveillance and Control of Infectious Diseases)
  • Systematic Review
  • Open Access
480 Views
26 Pages

16 October 2026

Background: Estimates of autism in criminal-justice and forensic populations vary widely, while studies involving autism-defined populations report heterogeneous justice outcomes. Broad pooling can obscure differences in recruitment, diagnostic ascer...