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13 Results Found

  • Article
  • Open Access
24 Citations
5,917 Views
14 Pages

Malaria infection during pregnancy is a major public health problem in sub-Saharan Africa. The World Health Organization (WHO) recommends that gestational and congenital malaria can be prevented by using intermittent preventive treatment of malaria i...

  • Systematic Review
  • Open Access
11 Citations
7,557 Views
33 Pages

Uptake and Effectiveness of Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine during Pregnancy in Africa: A Scoping Review

  • Gifty Osei Berchie,
  • Patience Fakornam Doe,
  • Theodora Dedo Azu,
  • Joyce Agyeiwaa and ,
  • Gifty Owusu,
  • Christian Makafui Boso,
  • Naomi Kyeremaa Yeboa,
  • Dorcas Frempomaa Agyare,
  • Irene Korkoi Aboh and
  • John Elvis Hagan
  • + 14 authors+ 9 authors

4 September 2024

Malaria poses a significant threat to pregnant women in sub-Saharan Africa, necessitating effective interventions like the intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP). However, challenges persist...

  • Article
  • Open Access
12 Citations
4,205 Views
20 Pages

Effectiveness of Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine in Pregnancy: Low Coverage and High Prevalence of Plasmodium falciparum dhfr-dhps Quintuple Mutants as Major Challenges in Douala, an Urban Setting in Cameroon

  • Carole Else Eboumbou Moukoko,
  • Loick Pradel Kojom Foko,
  • Angèle Ayina,
  • Bernard Tornyigah and ,
  • Annie Rachel Epote,
  • Ida Calixte Penda,
  • Patricia Epee Eboumbou,
  • Serge Bruno Ebong,
  • Gaetan Texier and
  • Albert Same Ekobo
  • + 8 authors+ 3 authors

Intermittent preventive treatment in pregnancy with sulfadoxine and pyrimethamine (IPTp-SP) is a key component in the malaria control strategy implemented in Africa. The aim of this study was to determine IPTp-SP adherence and coverage, and the impac...

(This article belongs to the Section Parasitic Pathogens)
  • Article
  • Open Access
22 Citations
8,065 Views
19 Pages

Effectiveness of Sulfadoxine–Pyrimethamine for Intermittent Preventive Treatment of Malaria and Adverse Birth Outcomes in Pregnant Women

  • Eulambius M. Mlugu,
  • Omary Minzi,
  • Muhammad Asghar,
  • Anna Färnert and ,
  • Appolinary A.R. Kamuhabwa and
  • Eleni Aklillu
  • + 1 author+ 0 author

Effectiveness of intermittent preventive treatment in pregnancy with sulfadoxine–pyrimethamine (IPTp-SP) for prevention of malaria and adverse birth outcomes can be compromised by parasites-resistance to sulfadoxine–pyrimethamine. This st...

(This article belongs to the Section Human Pathogens)
  • Article
  • Open Access
4 Citations
2,662 Views
15 Pages

A significant gap exists between high rates of antenatal care attendance and low uptake of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) in Senegal. This study aims to investigate whether IPTp-SP is delivered...

  • Article
  • Open Access
59 Citations
11,098 Views
11 Pages

Uptake of intermittent preventive therapy in pregnancy (IPTp) with sulfadoxine-pyrimethamine (IPTp-SP) is a clinically-proven method to prevent the adverse outcomes of malaria in pregnancy (MiP) for the mother, her foetus, and the neonates. The major...

  • Article
  • Open Access
11 Citations
7,653 Views
12 Pages

Factors Influencing Anti-Malarial Prophylaxis and Iron Supplementation Non-Compliance among Pregnant Women in Simiyu Region, Tanzania

  • Benatus Sambili,
  • Ronald Kimambo,
  • Yun Peng,
  • Elison Ishunga and ,
  • Edna Matasha,
  • Godfrey Matumu,
  • Rita Noronha and
  • David P. Ngilangwa
  • + 3 authors+ 0 author

Malaria and iron-deficient anemia during pregnancy pose considerable risks for the mother and newborn. Intermittent Preventive Treatment during pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) and iron supplement to prevent anemia to all pregnant...

  • Article
  • Open Access
886 Views
18 Pages

Prevalence of pfdhfr-pfdhps Sextuple and Gametocyte-Associated Quintuple Sulfadoxine-Pyrimethamine Resistance Mutations in Plasmodium falciparum Isolates from Pregnant Women in Mozambique

  • Yasmina Drissi-El Boukili,
  • Eduard Rovira-Vallbona,
  • Pieter Guetens,
  • Driss Chiheb and ,
  • Johanna Helena Kattenberg,
  • Luc Kestens,
  • Sonia Maria Mauricio Enosse,
  • Anna Rosanas-Urgell and
  • Paulo Arnaldo
  • + 4 authors+ 0 author

Intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) remains the main strategy to prevent malaria in pregnancy. However, continued drug pressure may also contribute to the emergence of resistant parasites and impact the gametocy...

(This article belongs to the Section Ticks)
  • Article
  • Open Access
8 Citations
1 Views
4 Pages

Prevalence of Dihydrofolate Reductase Gene Mutations in Plasmodium falciparum Isolate from Pregnant Women in Nigeria

  • Olusola Ojurongbe,
  • Bukola D. Tijani,
  • Adegboyega A. Fawole,
  • Oluwaseyi A. Adeyeba and
  • Juergen F. Kun

We assessed the prevalence of Plasmodium falciparum and the frequency of the dhfr triple mutation that is associated with antifolate drug resistance among P. falciparumisolates obtained from pregnant women in Ilorin, Nigeria. The study included 179 w...

  • Article
  • Open Access
6 Citations
5,209 Views
14 Pages

Prevention of Malaria in Pregnant Women and Its Effects on Maternal and Child Health, the Case of Centre Hospitalier de Kingasani II in the Democratic Republic of the Congo

  • Japhet Kabalu Tshiongo,
  • Trésor Zola Matuvanga,
  • Patrick Mitashi,
  • Vivi Maketa and ,
  • Henk D. F. H. Schallig,
  • Petra F. Mens,
  • Hypolite Muhindo Mavoko and
  • Junior Matangila Rika
  • + 3 authors+ 0 author

This study aimed to evaluate scientific evidence of the benefit of the use of insecticide-treated nets (ITNs) and Intermittent preventive treatment (IPT) on the birth weight of newborns and the hemoglobin level of the mother when used to prevent mala...

  • Review
  • Open Access
27 Citations
10,554 Views
19 Pages

Malaria infection during pregnancy is an important driver of maternal and neonatal health in endemic countries. Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention at each sc...

(This article belongs to the Special Issue Malaria Chemoprevention Strategies)
  • Systematic Review
  • Open Access
7 Citations
4,734 Views
24 Pages

Qualitative research on malaria in pregnancy (MiP) is incipient, therefore its contextual, experiential and symbolic associated factors are unknown. This study systematizes the qualitative research on MiP, describes knowledge, perceptions and behavio...

(This article belongs to the Special Issue Advances in Malaria Treatment and Prevention)
  • Article
  • Open Access
1 Citations
1,634 Views
17 Pages

Persistent and Circulating Plasmodium falciparum dhfr and dhps Mutations in Busia County, Western Kenya

  • Loise Ndung’u,
  • Kelvin Thiong’o,
  • Lewis Karani,
  • Stephen Gitahi and ,
  • Francis Kimani,
  • Mathew Piero Ngugi and
  • Daniel Kiboi
  • + 2 authors+ 0 author

20 February 2026

Malaria in pregnancy remains a major driver of poor maternal and neonatal health outcomes in sub-Saharan Africa. For decades, intermittent preventive treatment in pregnancy (IPTp), with sulphadoxine-pyrimethamine (SP), has mitigated malaria-associate...

(This article belongs to the Special Issue Parasitic Diseases in the Contemporary World)