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18 Results Found

  • Article
  • Open Access
20 Citations
4,976 Views
14 Pages

Malaria infection during pregnancy is a major public health problem in sub-Saharan Africa. The World Health Organization (WHO) recommends that gestational and congenital malaria can be prevented by using intermittent preventive treatment of malaria i...

  • Article
  • Open Access
52 Citations
9,795 Views
11 Pages

Uptake of intermittent preventive therapy in pregnancy (IPTp) with sulfadoxine-pyrimethamine (IPTp-SP) is a clinically-proven method to prevent the adverse outcomes of malaria in pregnancy (MiP) for the mother, her foetus, and the neonates. The major...

  • Systematic Review
  • Open Access
10 Citations
5,667 Views
33 Pages

Uptake and Effectiveness of Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine during Pregnancy in Africa: A Scoping Review

  • Gifty Osei Berchie,
  • Patience Fakornam Doe,
  • Theodora Dedo Azu,
  • Joyce Agyeiwaa,
  • Gifty Owusu,
  • Christian Makafui Boso,
  • Naomi Kyeremaa Yeboa,
  • Dorcas Frempomaa Agyare,
  • Irene Korkoi Aboh and
  • John Elvis Hagan
  • + 9 authors

4 September 2024

Malaria poses a significant threat to pregnant women in sub-Saharan Africa, necessitating effective interventions like the intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP). However, challenges persist...

  • Article
  • Open Access
10 Citations
3,633 Views
20 Pages

Effectiveness of Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine in Pregnancy: Low Coverage and High Prevalence of Plasmodium falciparum dhfr-dhps Quintuple Mutants as Major Challenges in Douala, an Urban Setting in Cameroon

  • Carole Else Eboumbou Moukoko,
  • Loick Pradel Kojom Foko,
  • Angèle Ayina,
  • Bernard Tornyigah,
  • Annie Rachel Epote,
  • Ida Calixte Penda,
  • Patricia Epee Eboumbou,
  • Serge Bruno Ebong,
  • Gaetan Texier and
  • Albert Same Ekobo
  • + 3 authors

Intermittent preventive treatment in pregnancy with sulfadoxine and pyrimethamine (IPTp-SP) is a key component in the malaria control strategy implemented in Africa. The aim of this study was to determine IPTp-SP adherence and coverage, and the impac...

  • Article
  • Open Access
21 Citations
6,699 Views
19 Pages

Effectiveness of Sulfadoxine–Pyrimethamine for Intermittent Preventive Treatment of Malaria and Adverse Birth Outcomes in Pregnant Women

  • Eulambius M. Mlugu,
  • Omary Minzi,
  • Muhammad Asghar,
  • Anna Färnert,
  • Appolinary A.R. Kamuhabwa and
  • Eleni Aklillu

Effectiveness of intermittent preventive treatment in pregnancy with sulfadoxine–pyrimethamine (IPTp-SP) for prevention of malaria and adverse birth outcomes can be compromised by parasites-resistance to sulfadoxine–pyrimethamine. This st...

  • Article
  • Open Access
9 Citations
5,497 Views
25 Pages

Malaria Prevention for Pregnant Women and Under-Five Children in 10 Sub-Saharan Africa Countries: Socioeconomic and Temporal Inequality Analysis

  • Denis Okova,
  • Akim Tafadzwa Lukwa,
  • Robinson Oyando,
  • Paidamoyo Bodzo,
  • Plaxcedes Chiwire and
  • Olufunke A. Alaba

Background: Malaria remains a public health challenge in low- and middle-income countries (LMICs). Despite gains from strategies like Insecticide-Treated Nets (ITNs) and Intermittent Preventive Treatment during pregnancy (IPTp), significant socioecon...

  • Article
  • Open Access
4 Citations
2,364 Views
15 Pages

A significant gap exists between high rates of antenatal care attendance and low uptake of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) in Senegal. This study aims to investigate whether IPTp-SP is delivered...

  • Review
  • Open Access
9 Citations
4,762 Views
15 Pages

Malaria in pregnancy is a public health challenge with serious negative maternal and newborn consequences. Intermittent preventive treatment (IPTp) with sulphadoxine-pyrimethamine is recommended for the control of malaria during pregnancy within ende...

  • Article
  • Open Access
2 Citations
3,784 Views
21 Pages

23 October 2019

Private transfer of wealth is a ubiquitous phenomenon in both urban and rural areas of China. This paper took an inflow private transfer payment as the research object and used the China Household Finance Survey data to analyze the impact of inward p...

  • Review
  • Open Access
20 Citations
8,818 Views
19 Pages

Malaria infection during pregnancy is an important driver of maternal and neonatal health in endemic countries. Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention at each sc...

  • Article
  • Open Access
10 Citations
7,317 Views
12 Pages

Factors Influencing Anti-Malarial Prophylaxis and Iron Supplementation Non-Compliance among Pregnant Women in Simiyu Region, Tanzania

  • Benatus Sambili,
  • Ronald Kimambo,
  • Yun Peng,
  • Elison Ishunga,
  • Edna Matasha,
  • Godfrey Matumu,
  • Rita Noronha and
  • David P. Ngilangwa

Malaria and iron-deficient anemia during pregnancy pose considerable risks for the mother and newborn. Intermittent Preventive Treatment during pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) and iron supplement to prevent anemia to all pregnant...

  • Article
  • Open Access
1 Citations
2,011 Views
12 Pages

Intermittent Preventive Treatment of Malaria in Pregnancy and the Impact on Neonates in African Countries as Assessed by Entropy Weight and TOPSIS Methods

  • Maria Tzitiridou-Chatzopoulou,
  • Georgia Zournatzidou,
  • Eirini Orovou,
  • Lazaros Lavasidis,
  • Arsenios Tsiotsias,
  • Panagiotis Eskitzis and
  • Dimitrios Papoutsis

18 October 2024

Background/Objectives: In regions of Africa with a high prevalence of malaria, pregnant women in their first or second trimester should be administered intermittent preventive treatment in pregnancy (IPTp). However, infants may contract malaria despi...

  • Article
  • Open Access
4 Citations
2,736 Views
19 Pages

Using regionally linked facility and household surveys, we measured the quality of integrated antenatal care and malaria in pregnancy services in Kenya, Namibia, Senegal, and Tanzania. We examined country heterogeneities for the association of integr...

  • Article
  • Open Access
8 Citations
1 Views
4 Pages

Prevalence of Dihydrofolate Reductase Gene Mutations in Plasmodium falciparum Isolate from Pregnant Women in Nigeria

  • Olusola Ojurongbe,
  • Bukola D. Tijani,
  • Adegboyega A. Fawole,
  • Oluwaseyi A. Adeyeba and
  • Juergen F. Kun

We assessed the prevalence of Plasmodium falciparum and the frequency of the dhfr triple mutation that is associated with antifolate drug resistance among P. falciparumisolates obtained from pregnant women in Ilorin, Nigeria. The study included 179 w...

  • Article
  • Open Access
4 Citations
3,883 Views
14 Pages

Prevention of Malaria in Pregnant Women and Its Effects on Maternal and Child Health, the Case of Centre Hospitalier de Kingasani II in the Democratic Republic of the Congo

  • Japhet Kabalu Tshiongo,
  • Trésor Zola Matuvanga,
  • Patrick Mitashi,
  • Vivi Maketa,
  • Henk D. F. H. Schallig,
  • Petra F. Mens,
  • Hypolite Muhindo Mavoko and
  • Junior Matangila Rika

This study aimed to evaluate scientific evidence of the benefit of the use of insecticide-treated nets (ITNs) and Intermittent preventive treatment (IPT) on the birth weight of newborns and the hemoglobin level of the mother when used to prevent mala...

  • Article
  • Open Access
14 Citations
8,559 Views
21 Pages

Cost Effectiveness Analysis of Optimal Malaria Control Strategies in Kenya

  • Gabriel Otieno,
  • Joseph K. Koske and
  • John M. Mutiso

Malaria remains a leading cause of mortality and morbidity among the children under five and pregnant women in sub-Saharan Africa, but it is preventable and controllable provided current recommended interventions are properly implemented. Better util...

  • Systematic Review
  • Open Access
5 Citations
3,915 Views
24 Pages

Qualitative research on malaria in pregnancy (MiP) is incipient, therefore its contextual, experiential and symbolic associated factors are unknown. This study systematizes the qualitative research on MiP, describes knowledge, perceptions and behavio...

  • Article
  • Open Access
271 Views
17 Pages

Persistent and Circulating Plasmodium falciparum dhfr and dhps Mutations in Busia County, Western Kenya

  • Loise Ndung’u,
  • Kelvin Thiong’o,
  • Lewis Karani,
  • Stephen Gitahi,
  • Francis Kimani,
  • Mathew Piero Ngugi and
  • Daniel Kiboi

20 February 2026

Malaria in pregnancy remains a major driver of poor maternal and neonatal health outcomes in sub-Saharan Africa. For decades, intermittent preventive treatment in pregnancy (IPTp), with sulphadoxine-pyrimethamine (SP), has mitigated malaria-associate...