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14 Results Found

  • Article
  • Open Access
2 Citations
1,497 Views
12 Pages

24 March 2025

Background and Objectives: Hypercapnic respiratory failure (HRF) is a critical clinical condition commonly encountered in acute exacerbations of chronic obstructive pulmonary disease (COPD), leading to high morbidity and mortality rates. The existing...

  • Article
  • Open Access
229 Views
14 Pages

DECAF: Deconvoluted Extracted Ion Chromatogram-Based Quantification of Therapeutic Oligonucleotides

  • Piotr Prostko,
  • Youzhong Liu,
  • Michał Aleksander Ciach,
  • Tatsiana Khamiakova,
  • Thomas De Vijlder and
  • Dirk Valkenborg

6 February 2026

Accurate quantification in LC–MS experiments becomes challenging when analytes overlap both chromatographically and in mass spectra, as conventional extracted ion chromatogram-based methods can yield biased results by double-counting shared iso...

  • Article
  • Open Access
7 Citations
6,505 Views
12 Pages

DeCAF—Discrimination, Comparison, Alignment Tool for 2D PHarmacophores

  • Marta M. Stepniewska-Dziubinska,
  • Piotr Zielenkiewicz and
  • Pawel Siedlecki

Comparison of small molecules is a common component of many cheminformatics workflows, including the design of new compounds and libraries as well as side-effect predictions and drug repurposing. Currently, large-scale comparison methods rely mostly...

  • Article
  • Open Access
4 Citations
6,867 Views
9 Pages

Acute Caffeine and Coconut Oil Intake, Isolated or Combined, Does Not Improve Running Times of Recreational Runners: A Randomized, Placebo-Controlled and Crossover Study

  • Gabrielle de Lima Borba,
  • Julianne Soares de Freitas Batista,
  • Ludmilla Marques Queiroz Novais,
  • Myrnzzia Beatriz Silva,
  • João Batista da Silva Júnior,
  • Paulo Gentil,
  • Ana Clara Baretto Marini,
  • Bruna Melo Giglio and
  • Gustavo Duarte Pimentel

20 July 2019

The aim was to evaluate the effect of caffeine (CAF) and extra virgin coconut oil (CO), isolated or combined, on running performance in runners. Methods: A randomized, placebo-controlled, and crossover study was conducted with thirteen recreational r...

  • Article
  • Open Access
13 Citations
14,318 Views
18 Pages

Mechanistic Study of Coffee Effects on Gut Microbiota and Motility in Rats

  • Shrilakshmi Hegde,
  • Daniel W. Shi,
  • John C. Johnson,
  • Ramasatyaveni Geesala,
  • Ke Zhang,
  • You-Min Lin and
  • Xuan-Zheng Shi

18 November 2022

Consumption of coffee has benefits in postoperative ileus. We tested the hypothesis that the benefits may be related to the effects of coffee on gut microbiota and motility and studied the mechanisms of action in rats. The in vitro and in vivo effect...

  • Feature Paper
  • Article
  • Open Access
11 Citations
6,587 Views
14 Pages

Caffeine-Containing Energy Shots Cause Acute Impaired Glucoregulation in Adolescents

  • Jane Shearer,
  • Raylene A. Reimer,
  • Dustin S. Hittel,
  • Mackenzie A. Gault,
  • Hans J. Vogel and
  • Matthias S. Klein

16 December 2020

Caffeine-containing, nutritionally fortified energy shots are consumed at high rates by adolescents, yet little is known about their metabolic impact. The purpose of this study was to examine the consequences of small format, caffeinated energy shots...

  • Article
  • Open Access
37 Citations
7,336 Views
21 Pages

7 September 2019

In recent years, the shift to a circular economy (CE) has become an increasingly important component of the European Union’s development strategy. However, no consensus has yet been reached on the depth of the transformation this implies, nor o...

  • Article
  • Open Access
833 Views
23 Pages

30 September 2025

Multiple unmanned aerial vehicle (UAV) systems have attracted considerable research interest due to their broad applications, such as formation control. However, decentralized UAV formation faces challenges stemming from limited local observations, w...

  • Article
  • Open Access
17 Citations
5,002 Views
16 Pages

Food Waste Materials as Low-Cost Adsorbents for the Removal of Volatile Organic Compounds from Wastewater

  • Maria Agostina Frezzini,
  • Lorenzo Massimi,
  • Maria Luisa Astolfi,
  • Silvia Canepari and
  • Antonella Giuliano

17 December 2019

The aim of this work was to study the potential of food waste materials (banana peel, potato peel, apple peel, lemon peel, coffee waste, decaf coffee waste, grape waste, and carob peel) as low-cost adsorbents for the removal of aliphatic and aromatic...

  • Article
  • Open Access
5 Citations
2,924 Views
17 Pages

Association between Dietary Patterns and Metabolic Syndrome Risk Factors: A Cross-Sectional Study of Christian Orthodox Church Fasters and Non-Fasters in Greece

  • Anna Kokkinopoulou,
  • Niki Katsiki,
  • Ioannis Pagkalos,
  • Nikolaos E. Rodopaios,
  • Alexandra-Aikaterini Koulouri,
  • Eleni Vasara,
  • Sousana K. Papadopoulou,
  • Petros Skepastianos,
  • Maria Hassapidou and
  • Anthony G. Kafatos

19 September 2023

It is well known that the Mediterranean diet contributes to healthy living, prevention of non-communicable diseases, and longevity. A cross-sectional study was conducted with participants from Greece who follow the Mediterranean diet and were further...

  • Proceeding Paper
  • Open Access
2 Citations
3,087 Views
5 Pages

Mass Transfer of Dichloromethane from EU Retail Roast and Ground Decaffeinated Coffee into Prepared Beverages

  • Massimiliano Fabian,
  • Oliver Süße-Herrmann,
  • Gregory McGaffin and
  • Johannes Hielscher

14 October 2024

Dichloromethane (DCM) is extensively used around the globe in various applications, such as in closed industrial installations for food processing or pharmaceutical extractions (vitamins, antibiotics, etc.). In the coffee sector, it is used as an ext...

  • Article
  • Open Access
38 Citations
12,216 Views
14 Pages

Caffeinated Coffee, Decaffeinated Coffee and Endometrial Cancer Risk: A Prospective Cohort Study among US Postmenopausal Women

  • Ayush Giri,
  • Susan R. Sturgeon,
  • Nicole Luisi,
  • Elizabeth Bertone-Johnson,
  • Raji Balasubramanian and
  • Katherine W. Reeves

2 November 2011

There is plausible biological evidence as well as epidemiologic evidence to suggest coffee consumption may lower endometrial cancer risk. We evaluated the associations between self-reported total coffee, caffeinated coffee and decaffeinated coffee, a...

  • Article
  • Open Access
8 Citations
3,627 Views
16 Pages

DNA Damage Induction Alters the Expression of Ubiquitin and SUMO Regulators in Preimplantation Stage Pig Embryos

  • Zigomar da Silva,
  • Werner Giehl Glanzner,
  • Luke Currin,
  • Mariana Priotto de Macedo,
  • Karina Gutierrez,
  • Vanessa Guay,
  • Paulo Bayard Dias Gonçalves and
  • Vilceu Bordignon

25 August 2022

DNA damage in early-stage embryos impacts development and is a risk factor for segregation of altered genomes. DNA damage response (DDR) encompasses a sophisticated network of proteins involved in sensing, signaling, and repairing damage. DDR is regu...

  • Study Protocol
  • Open Access
530 Views
13 Pages

Novel Biomarkers for Prognostic Assessment of Patients with Acute Exacerbation of COPD in the Emergency Department—Tools to Enhance the Quality of Care in Critical Patient Management

  • Raluca Mihaela Tat,
  • Sonia Luka,
  • Eugenia Maria Lupan-Mureșan,
  • George Teo Voicescu,
  • Luca David,
  • Adela Golea and
  • Ștefan Cristian Vesa

Background/Objectives: Chronic obstructive pulmonary disease (COPD) remains a major global health problem, affecting over 300 million people worldwide. Its high morbidity and mortality rates impose substantial psychosocial and financial burdens on pa...