Memories of, Anecdotes about, and Thoughts on Two Pioneers of the Complement Field —Sir Peter J. Lachmann, 1931–2020 and Robert B. Sim, 1951–2021

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viral Immunology, Vaccines, and Antivirals".

Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 21734

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Guest Editor
Department of Hygiene, Microbiology and Social Medicine, Medical University Innsbruck, A-6020 Innsbruck, Austria
Interests: Complement: activation, inhibition, terminal pathway, deficiencies, polymorphisms, monoclonal antibodies; Candida albicans: 'molecular mimicry', integrin-analogue, complement receptors, adhesion, secreted aspartic proteases, complement evasion; EHEC: virulence factors, influence of complement, HUS
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Dear Colleagues,

With the passing of two world-famous scientists in the field of complement research in 2020/2021, not only the European complement science community but also the International complement society are experiencing a great loss. Several obituaries are presently being compiled to honor both gold medal winners of the European Complement Network, stressing the seminal scientific achievements both made over the last few decades.

Complement is quite a small scientific field, and despite the fact that in the 1960s to 1980s, a lot of fighting between scientific groups dominated the atmosphere at conferences, the field developed and matured in the following decades, and yearly international meetings alternating between complement workshops and meetings on complement in human diseases took the form of a kind of big family gathering. This, of course, included necessary and “healthy” rivalry, but this was almost always handled fairly and with style. This fostered the change of personnel, and especially Peter and Bob were not only reliable colleagues, but also extremely kind hosts for dozens of scientists and students.

Viruses, a journal in which Sir Peter J. Lachmann served as Guest editor to the end, has kindly agreed to establish a Section where you, as a fellow complementologist or scientist, can present your memories of one or both of our deceased colleagues, mention some funny anecdotes about them or deep thoughts on these two pioneers of the complement field, the main idea being to show the very special human beings behind the successful scientists to keep our memories of them alive.

We hereby kindly ask you to submit your work celebrating not only these two extraordinary colleagues’ scientific achievements, but even more so, or even exclusively, any memories you may have of and/or with them that you would like to share.

Prof. Dr. Reinhard Würzner
Guest Editor

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Keywords

  • obituary
  • Peter J. Lachmann
  • Robert B. Sim
  • immunology
  • complement
  • European Complement Network (ECN)
  • International Complement Society (ICS)
  • European Meeting on Complement in Human Disease (EMCHD)
  • International Complement Workshop (ICW)

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Published Papers (14 papers)

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Editorial

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3 pages, 552 KiB  
Editorial
In Memory of Two Pioneers in the Complement Field—Sir Peter J. Lachmann, 1931–2020 & Robert B. Sim, 1951–2021
by Reinhard Würzner
Viruses 2021, 13(3), 431; https://doi.org/10.3390/v13030431 - 08 Mar 2021
Cited by 1 | Viewed by 1368
Abstract
With deep sadness, we have to accept that two cornerstones, not just of British immunology, but also world-famous scientists in the field of complement research, passed away within the margin of a few weeks: Peter Julius Lachmann on 26 December 2020 (Figure 1), [...] Read more.
With deep sadness, we have to accept that two cornerstones, not just of British immunology, but also world-famous scientists in the field of complement research, passed away within the margin of a few weeks: Peter Julius Lachmann on 26 December 2020 (Figure 1), and Robert Braidwood Sim (known to everyone as Bob) on 6 February 2021 (Figure 2) [...] Full article
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6 pages, 27871 KiB  
Obituary
A Tribute to Robert (Bob) Sim—Personal Memories of Working in Bob’s Lab
by Samantha Williams and Alexander Steinkasserer
Viruses 2021, 13(9), 1696; https://doi.org/10.3390/v13091696 - 26 Aug 2021
Viewed by 1442
Abstract
This article is intended as a tribute to Robert B. Sim through the sharing of personal memories and anecdotes from two of Bob’s lab members who worked in his lab between 1989 to 1994. Full article
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1 pages, 145 KiB  
Obituary
Robert B. Sim—Tribute
by Anna Erdei
Viruses 2021, 13(9), 1681; https://doi.org/10.3390/v13091681 - 25 Aug 2021
Viewed by 982
Abstract
I met Bob in 1985, when I moved with my family to Oxford for a two-year EMBO fellowship at the MRC Immunochemistry Unit [...] Full article
3 pages, 427 KiB  
Obituary
In Memory of Sir Peter J. Lachmann, 1931–2020—Bees, Tickover, Factor I and Complement
by Seppo Meri
Viruses 2021, 13(8), 1629; https://doi.org/10.3390/v13081629 - 17 Aug 2021
Viewed by 1484
Abstract
We were all very sorry to hear that our highly esteemed colleague and one of the true pioneers of complement research, Professor, Sir Peter J [...] Full article
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2 pages, 299 KiB  
Obituary
A Memory of Professor Robert B. Sim, D. Phil
by Chack-Yung Yu
Viruses 2021, 13(8), 1569; https://doi.org/10.3390/v13081569 - 09 Aug 2021
Viewed by 1174
Abstract
Many of us were saddened to learn about the passing of Dr [...] Full article
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3 pages, 245 KiB  
Obituary
Sir Peter Lachmann—Outstanding and Inspirational Immunologist
by Ian McConnell
Viruses 2021, 13(8), 1534; https://doi.org/10.3390/v13081534 - 03 Aug 2021
Viewed by 1354
Abstract
Sir Peter Lachmann was an exceptional and gifted scientist whose intellectual contributions to biomedical science have been immense.[...] Full article
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9 pages, 3498 KiB  
Obituary
A Personal Tribute to Robert B. Sim with Reflections on Our Work Together on Factor H
by Anthony J. Day
Viruses 2021, 13(7), 1256; https://doi.org/10.3390/v13071256 - 28 Jun 2021
Viewed by 1739
Abstract
Robert (Bob) Sim had a profound effect on almost every aspect of my approach to scientific research, acting as a mentor and moral compass through the many different stages of my career [...] Full article
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3 pages, 1679 KiB  
Obituary
Professor Robert Braidwood Sim—“Bob”—A Career in Complement Research Spanning 1973–2021
by Kenneth Reid
Viruses 2021, 13(7), 1190; https://doi.org/10.3390/v13071190 - 22 Jun 2021
Cited by 1 | Viewed by 1561
Abstract
Bob joined the MRC Immunochemistry Unit, within the Department of Biochemistry at Oxford University, as a D [...] Full article
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3 pages, 705 KiB  
Obituary
Robert Braidwood (Bob) Sim. 1951–2021: A Disciple’s Perspective
by Álvaro Díaz
Viruses 2021, 13(6), 1111; https://doi.org/10.3390/v13061111 - 10 Jun 2021
Cited by 3 | Viewed by 1883
Abstract
Three and a half months ago, we were very much saddened by the news of Bob Sim’s passing away [...] Full article
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5 pages, 2744 KiB  
Obituary
Memories of Bob Sim—Genius Complementologist and Cheerful Travel Companion
by Reinhard Würzner, Francesco Tedesco, Peter Garred, Tom E. Mollnes, Lennart Truedsson, Malcolm W. Turner, Yngve Sommarin, Jörgen Wieslander and Mohamed R. Daha
Viruses 2021, 13(6), 1068; https://doi.org/10.3390/v13061068 - 04 Jun 2021
Cited by 1 | Viewed by 2429
Abstract
Shortly before his 70th birthday, Robert B [...] Full article
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3 pages, 154 KiB  
Obituary
Professor Sir Peter J. Lachmann, FRS, FMedSci (1931–2020)
by Richard A. Harrison and B. Paul Morgan
Viruses 2021, 13(6), 1012; https://doi.org/10.3390/v13061012 - 28 May 2021
Cited by 1 | Viewed by 1418
Abstract
As members of the International Complement Society (ICS) will be aware, Professor Sir Peter Lachmann sadly passed away, peacefully and at home, on 26th December 2020 [...] Full article
2 pages, 280 KiB  
Obituary
Sir Peter J. Lachmann and Prof. Robert B. Sim: Gone but Will Never Be Forgotten!
by Berhane Ghebrehiwet
Viruses 2021, 13(5), 858; https://doi.org/10.3390/v13050858 - 08 May 2021
Cited by 1 | Viewed by 1184
Abstract
In addition to the ongoing COVID-19 pandemic, which has brought an unexpected global gloom, the beginning of this year was also particularly cruel to the complement field, as two of our greatest and dearest members—Sir Peter Lachmann and Prof [...] Full article
4 pages, 1066 KiB  
Obituary
Complement’s C1 Complex, Factor H and the X Factor: A Personal Tribute to Prof. Robert B. Sim
by Uday Kishore
Viruses 2021, 13(5), 793; https://doi.org/10.3390/v13050793 - 29 Apr 2021
Cited by 1 | Viewed by 1456
Abstract
It is with great sadness that I am writing this obituary for my mentor, colleague and friend, Bob, i [...] Full article
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1 pages, 158 KiB  
Obituary
Bob Sim, Memories from Oxford and Grenoble
by Gérard J. Arlaud
Viruses 2021, 13(4), 561; https://doi.org/10.3390/v13040561 - 26 Mar 2021
Cited by 1 | Viewed by 1007
Abstract
I initially met Bob and Edith Sim when they moved to Grenoble in 1976 for a two-year fellowship at the Centre d’Etudes Nucléaires [...] Full article
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