Advances in Pestivirus Research

Dear Colleagues,

Pestiviruses like classical swine fever virus and bovine viral diarrhea virus are causative agents of economically highly important diseases of livestock. The identification of related viruses in various hosts including pigs, domestic and wild ruminants as well as bats, rodents, harbor porpoise and pangoline has resulted in the establishment of eleven approved pestivirus species and a growing number of additional tentative species. Apart from the tremendous impact on animal health and economic welfare, several unique properties of pestiviruses like the establishment of persistent infection by specifically acquired immunotolerance, the existence of non-cytopathogenic and cytopathogenic virus biotypes, the endoribonuclease function of the glycoprotein E^rns, and their relation to human hepatitis C virus, another member of the Flaviviridae family has prompted detailed studies of these viruses. This Special Issue aims at summarizing recent advances in epidemiology, diagnosis, and control of pestivirus-induced diseases as well as pathogenesis, virus–host interaction, mechanisms of viral replication, and evolution of these fascinating viruses.

Prof. Dr. Paul Becher
Dr. Nicolas Ruggli
Prof. Dr. Norbert Tautz
Guest Editors

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