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Veterinary Sciences
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Evaluation of Feeds and Additives on Metabolic or Metabolomic Research...
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Evaluation of Feeds and Additives on Metabolic or Metabolomic Research on Animal Production—2nd Edition

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Nutritional and Metabolic Diseases in Veterinary Medicine".

Deadline for manuscript submissions: 18 December 2026 | Viewed by 795

Editors

Dr. Héctor Aarón Lee-Rangel

E-Mail Website
Guest Editor
Facultad de Agronomía y Veterinaria, Centro de Biociencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78321, Mexico
Interests: animal nutrition; metabolism; fetal programming; productivity; animal science; metabolomic
Special Issues, Collections and Topics in MDPI journals
Dr. Pedro Abel Hernandez Garcia

E-Mail Website
Guest Editor
Centro Universitario UAEM Amecameca, Universidad Autónoma del Estado de Mexico, Estado de México 5900, Mexico
Interests: feed; dietary supplementation; productivity; nutritional additives

Special Issue Information

Dear Colleagues,

Following the great success of our previous Special Issue, “Evaluation of Feeds and Additives on Metabolic or Metabolomic Research on Animal Production”, which successfully published twelve high-quality articles covering a broad range of topics, we are pleased to announce the launch of Volume II.

Animal production is one of the main pillars of global food security; to achieve desired performance, it is necessary to provide sufficient nutrients for maintenance, growth, lactation, egg production, and good health. The quality of diets depends on the ingredients or additives used. For this reason, the nutritional values of feed ingredients should be accurately evaluated for sustainable animal production. Due to this, non-conventional ingredients and feed additives are widely used to assess the effects on feed efficiency, animal health, growth performance, immune function, metabolism, metabolomic alterations, and ruminal microbiota during fermentation, all resulting in improved animal performance or product quality.

This Issue will focus on research evaluating the feasibility of using non-conventional ingredients and novel feed additives.

Dr. Héctor Aarón Lee-Rangel
Dr. Pedro Abel Hernandez Garcia
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Veterinary Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cattle
  • sheep and goats
  • swine, poultry, rabbit
  • feed additives
  • non-conventional ingredients
  • plant secondary metabolites
  • feed evaluation
  • animal performance
  • greenhouse gases
  • gut health
  • nutrient metabolism
  • sustainability
  • metabolism
  • metabolomic

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Published Papers (1 paper)

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Research

23 pages, 585 KB  
Article
Dietary L-Arginine and Zinc Oxide Nanoparticles Improve Growth Performance, Oxidative Status, Immunity, and Intestinal Integrity Indicators in Heat-Stressed Weaned Rabbits
by Tahani M. I. Al-Hazani, Amirah S. Alahmari, Manal A. Babaker, Ahmed M. Elbaz, Hagar E. Mohammed, Hany A. Thabet, Eman Kamel M. Khalfallah, Ahmed Ateya, Rowa K. Zarah, Khairiah Mubarak Alwutayd and Assem Abdou
Vet. Sci. 2026, 13(6), 598; https://doi.org/10.3390/vetsci13060598 - 19 Jun 2026
Viewed by 553
Abstract
This study evaluated the effects of adding zinc oxide nanoparticles (ZnNP), L-arginine (L-Arg), or a combination of both to the diets of growing rabbits to mitigate the physiological and productive consequences of heat stress. Two hundred and eighty 35-day-old New Zealand White rabbits [...] Read more.
This study evaluated the effects of adding zinc oxide nanoparticles (ZnNP), L-arginine (L-Arg), or a combination of both to the diets of growing rabbits to mitigate the physiological and productive consequences of heat stress. Two hundred and eighty 35-day-old New Zealand White rabbits were randomly assigned to four experimental treatments, with 70 rabbits per treatment and seven replicates (10 rabbits/replicate). The control group (Ctr) received the base diet without additives, while the diets of the other groups were fortified with arginine (L-Arg; 3 g/kg), zinc oxide nanoparticles (ZnNP; 40 mg/kg), or a combination of both (Arg-Zn). The results showed that the combined Arg-Zn significantly improved weight gain rate, feed conversion rate, carcass weight, and nutrient digestibility compared to the control group (p < 0.05). At the physiological level, we observed increased serum levels of total antioxidant capacity (T-AOC), glutathione peroxidase (GPx), superoxide dismutase (SOD), immunoglobulin G (IgG), immunoglobulin A (IgA), and triiodothyronine (T3), along with decreased levels of malondialdehyde (MDA), alanine aminotransferase (ALT), and aspartate aminotransferase (AST, p < 0.05) in Arg-Zn-fed rabbits. However, adding the Arg-Zn mixture contributed to a reduction in pathogenic bacteria counts and increased the volatile fatty acid (VFA) levels. At the molecular level, the gene expression of the inflammatory cytokines IL-6 and tumor necrosis factor alpha (TNF-α) decreased; however, the gene expression of claudins-1 (CLDN-1), cationic amino acid transporter-1 (CAT-1), mucin-2 (MUC-2), sodium-glucose co-transporter-1 (SGLT-1), and interferon gamma (IFNγ) increased (p < 0.05) in Arg-Zn-fed rabbits. These results suggest that dietary supplementation with ZnNP and L-Arg may serve as an effective nutritional strategy for improving growth performance, antioxidant status, immune function, and intestinal integrity in rabbits exposed to high ambient temperatures. Full article
(This article belongs to the Special Issue Evaluation of Feeds and Additives on Metabolic or Metabolomic Research on Animal Production—2nd Edition)
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