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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Developing Recombinant Vaccines and Immunotherapy Strategies for Emerging Viral Diseases

edited by

Emmanuel Datan

and

Athanasios Tsakris

submission deadline 31 Mar 2026 | Viewed by 276 | Submission Open

Keywords: emerging viral diseases; recombinant vaccines; immunotherapy; vaccine development; immune modulation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Veterinary Antiparasitic Vaccines

edited by

Miriam Tendler

and Marília Sirianni dos Santos Almeida

submission deadline 31 Mar 2026 | Viewed by 266 | Submission Open

Keywords: anti-parasitic vaccines; veterinary vaccines; vaccine manufacturing platforms; helminths; One Health; zoonosis; Immunization Agenda 2030

(This special issue belongs to the Section Veterinary Vaccines)

Influenza Virus Infections, Vaccines and Diagnosis

edited by

Roberta Antonia Diotti

, Isabel Pagani and Valeria Caputo

submission deadline 31 Mar 2026 | Viewed by 256 | Submission Open

Keywords: influenza; avian influenza; monoclonal antibodies; vaccine; therapy; infection

(This special issue belongs to the Section Influenza Virus Vaccines)

Strategies and Innovations to Recover Post-Pandemic Losses in Routine Immunization Coverage

edited by Noha H. Farag

submission deadline 31 Mar 2026 | Viewed by 254 | Submission Open

Keywords: vaccines; immunization; pandemic; vaccine preventable diseases; interventions

(This special issue belongs to the Section Vaccines and Public Health)

Vaccine Development for Influenza Virus: 2nd Edition

edited by

Mingtao Zeng

and

Ganesh Yadaigiri

submission deadline 31 Mar 2026 | Viewed by 248 | Submission Open

Keywords: influenza vaccine; adjuvant; mRNA vaccine; novel vaccine technology; nanotechnology; immune response; animal; human

(This special issue belongs to the Section Influenza Virus Vaccines)

Long-Term Immunity and Booster Strategies for COVID-19 Vaccines

edited by Alejo Erice and Ortiz De Lejarazu

submission deadline 31 Mar 2026 | Viewed by 136 | Submission Open

Keywords: SARS-CoV-2; mRNA vaccines; long-term immunity; immune imprinting; hybrid immunity; booster strategies

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Research on Immune Response and Vaccines: 2nd Edition

edited by James Galloway

submission deadline 30 Apr 2026 | 14 articles | Viewed by 58122 | Submission Open

Keywords: vaccines; immunogenicity; antigen recognition; adaptive immunity; cytokine response COVID-19; influenza; HPV; tuberculosis (BCG); malaria; HIV

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Varicella and Zoster Vaccination

edited by

Peter Maple

submission deadline 30 Apr 2026 | 14 articles | Viewed by 41618 | Submission Open

Keywords: varicella-zoster virus; chickenpox; shingles; vaccination; epidemiology; geographical regions; neurological diseases; SARS-CoV-2

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Human Papillomavirus Vaccine Against Cervical Cancer: New Usage Strategies and Coverage Issues

edited by

Luca Giannella

and

Andrea Ciavattini

submission deadline 30 Apr 2026 | 7 articles | Viewed by 29598 | Submission Open

Keywords: HPV vaccination coverage; HPV vaccination after conization; HPV vaccination in fertility-sparing treatment; male HPV vaccination HPV; vaccination after hysterectomy; tools for HPV vaccination implementation; HPV genotype in pre-invasive and invasive cervical pathology; HPV vaccination in vaginal pathology; HPV vaccination in vulvar pathology

(This special issue belongs to the Section Human Papillomavirus Vaccines)

COVID-19 Vaccination and Public Health: Addressing Global, Regional and Within-Country Inequalities

edited by

Dimitris Papamichail

and

Pietro Ferrara

submission deadline 30 Apr 2026 | 11 articles | Viewed by 21415 | Submission Open

Keywords: COVID-19 vaccine; population impact of COVID-19 vaccination; public health surveillance; health inequalities; access

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Production of Plant-Based Vaccines and Therapeutics

edited by Laurence K. Grill, John Howard and Kelvin Phiri

submission deadline 30 Apr 2026 | 2 articles | Viewed by 10867 | Submission Open

Keywords: plant-produced; viral-vectored; therapeutics; vaccines; tobacco mosaic virus (TMV)

Novel Vaccine Designs to Enhance the Engagement of Innate and Adaptive Immunity

edited by

Martin H. Bluth

and

Fangfeng Yuan

submission deadline 30 Apr 2026 | 4 articles | Viewed by 7305 | Submission Open

Keywords: vaccine; innate immunity; adaptive immunity; infectious disease; novel strategy; antigen delivery; protein engineering; adjuvants

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Personalised Cancer Vaccines

edited by Andrew L. Coveler

submission deadline 30 Apr 2026 | 3 articles | Viewed by 4417 | Submission Open

Keywords: peptide vaccines; mRNA vaccines; DNA vaccines; cancer vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Advancing Health: Vaccination and Infectious Disease Prevention in Pregnant Women, Neonates, Infants, and Children

edited by

Eleni Vergadi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2455 | Submission Open

Keywords: infectious diseases; maternal immunization; pediatric infection control; immunization coverage; health equity; immunization strategies; vaccine safety

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines and Immunization: Measles, Mumps, and Rubella

edited by Nobuhiko Okabe

submission deadline 30 Apr 2026 | 2 articles | Viewed by 1768 | Submission Open

Keywords: measles; mumps; rubella; SSPE; hearing loss; CRS; immune mechanism; epidemiology; resurgence; life-course immunization

(This special issue belongs to the Section Epidemiology and Vaccination)

Immune Responses in Patients with Chronic Disease After Vaccination

edited by

Nikola Stojanović

and

Marko Baralic

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1385 | Submission Open

Keywords: immunity; vaccine; chronic kidney disease; glomerulonephritis; systemic lupus erythematosus; vasculitis; kidney transplant; schizophrenia; bipolar disorder; diabetes

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Antiviral Immunity and Vaccine Development

edited by

Caijun Sun

and Tao Yu

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1228 | Submission Open

Keywords: antiviral innate immunity; adaptive immune responses; viral pathogenesis; immune evasion; host– virus interactions; antiviral vaccine development; vaccine design; novel vaccine platforms; vaccine adjuvants; vaccines and therapeutics

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Immune Response to Dengue Viral Infection

edited by

Bo Peng

and Xiaolu Shi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1213 | Submission Open

Keywords: dengue virus infection; immune response; immunity; viral infection

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Influenza Vaccines and Influenza Vaccination in Europe

edited by George Kassianos

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1143 | Submission Open

Keywords: vaccines; vaccine design; influenza; vaccination rates; vaccine efficacy; effectiveness; vaccine safety; vaccine development; adjuvant; recombinant influenza vaccine; cell-based; egg-derived; mRNA; vaccination strategies; vaccine response; antivirals

(This special issue belongs to the Section Influenza Virus Vaccines)

BCG Vaccine and Beyond: Innovations in Tuberculosis Vaccination and Inflammation-Related Disease Prevention

edited by

Xiao-Yong Fan

and

Zhi-Dong Hu

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1116 | Submission Open

Keywords: tuberculosis; vaccine; vaccination; immune response; adjuvant; T-cell; immune memory; adaptive immunity; innate immune memory; correlates of protection

(This special issue belongs to the Section Vaccines against Infectious Diseases)

New Horizons in the Fight Against Vector-Borne Diseases and Parasitic Infestations: From Basic Research to Applied Studies in Vaccines

edited by

Rodolfo Cordeiro Giunchetti

and

Maykelin Fuentes Zaldivar

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1101 | Submission Open

Keywords: vaccine; global health; neglected diseases; vectors

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines for Poultry Viruses

edited by

Dingxiang Liu

and Ying Liao

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1034 | Submission Open

Keywords: poultry viruses; vaccines; recombinant vaccines; vector-based vaccines; DNA/mRNA vaccines; vaccine delivery; adjuvants; vaccine efficacy

(This special issue belongs to the Section Veterinary Vaccines)

Immunological Responses to mRNA Vaccines

edited by Hyeri Seok

submission deadline 30 Apr 2026 | Viewed by 363 | Submission Open

Keywords: infectious; vaccine; immune response; immunogenicity; vaccine-induced immunity

The Need for an HIV Vaccine in the Era of Highly Effective PrEP

edited by Michele Peake Andrasik, William O. Hahn and Susan P. Buchbinder

submission deadline 30 Apr 2026 | Viewed by 339 | Submission Open

Keywords: HIV; vaccines; HIV prevention; bnAbs; clinical trials

(This special issue belongs to the Section HIV Vaccines)

Recent Advances and Strategies for the Management of CIN and HPV Eradication Starategies for the Prevention of Uterine Cervical Cancer

edited by

Masaru Sakamoto

submission deadline 30 Apr 2026 | Viewed by 289 | Submission Open

Keywords: CIN; 9-valent HPV vaccine; HPV L2-VLP vaccine; HPV therapeutic vaccine; endocervical conization; laser vaporization; PDT

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Oral Vaccines: Challenges, Immunity and Therapeutic Advances

edited by Amin Safa

submission deadline 30 Apr 2026 | Viewed by 282 | Submission Open

Keywords: oral vaccines; mucosal immunity; Peyer’ s patches; nanoparticles; probiotic delivery; cancer immunotherapy; gastrointestinal barriers; antigen presentation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

State of the Art of Flavivirus Virus Research

edited by

Tomoyoshi Komiya

submission deadline 30 Apr 2026 | Viewed by 251 | Submission Open

Keywords: flavivirus; vaccine; infection control; diagnosis; epidemiology

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Factors Influencing Vaccine Uptake and Immunization Outcomes

edited by Sitong Luo, Meiqi Xin and

Zixin Wang

submission deadline 30 Apr 2026 | Viewed by 222 | Submission Open

Keywords: vaccination; vaccine uptake; immunization

(This special issue belongs to the Section Vaccines and Public Health)

Genetically Engineered Mouse Models in Vaccine Development

edited by Deshan Ren and

Bingqian Qu

submission deadline 30 Apr 2026 | Viewed by 185 | Submission Open

Keywords: vaccine; immunogenicity; knockout; knockin; transgenic mice; humanized mice; xenografts; NCG/NKG/NRG/NSG; viruses

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

New Challenges in Vaccines and Vaccination: A Public Health Perspective

edited by

Marcello Guido

and

Antonella Zizza

submission deadline 30 Apr 2026 | Viewed by 125 | Submission Open

Keywords: vaccine effectiveness/efficacy; vaccination strategies; tailored approaches for different populations; public health

(This special issue belongs to the Section Vaccines and Public Health)

Tumor Vaccines: Current Processes, Prevailing Challenges and Future Perspectives

edited by Xingxing He and Honglin Jin

submission deadline 1 May 2026 | 8 articles | Viewed by 29839 | Submission Open

Keywords: tumor vaccine; mRNA vaccine; personalized medicine; adjuvant; delivery strategies; cancer immunotherapy; personalized vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Exploring Cutaneous Autoimmune Disease Flares in the Wake of COVID-19 Infection and Vaccination

edited by Angeliki-Victoria Roussaki-Schulze, Efterpi Zafiriou and

Emmanouil Karampinis

submission deadline 10 May 2026 | Viewed by 465 | Submission Open

Keywords: COVID-19 infection; COVID-19 vaccination; psoriasis; inflammatory dermatoses; alopecia; bullous dermatoses; adverse reactions; exanthem

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Swine Vaccines and Vaccination

edited by

Fanzhi Kong

submission deadline 15 May 2026 | 4 articles | Viewed by 4094 | Submission Open

Keywords: swine fever; classical swine fever virus; african swine fever virus; live attenuated vaccines; subunit vaccines; nanopartical vaccines

(This special issue belongs to the Section Veterinary Vaccines)

Vaccination and Treatments Against Viral Hepatitis: Achievements, Challenges and Perspectives, 2nd Edition

edited by

Bárbara Vieira Do Lago

and

Vinicius M. Mello

submission deadline 20 May 2026 | Viewed by 257 | Submission Open

Keywords: vaccination; treatments; viral hepatitis; hepatitis A– E

(This special issue belongs to the Section Hepatitis Virus Vaccines)

Innovative Vaccines and Technologies to Address Tropical Parasitic Diseases

edited by

Cecilia Maria Perez Brandan

Iván Marcipar

and Fernando Sanchez-Valdez

submission deadline 30 May 2026 | Viewed by 206 | Submission Open

Keywords: tropical parasitic diseases; vaccine development; chimeric and multiepitope vaccines; immunomodulation and adjuvants; host– parasite interaction; biotechnology-based vaccine platforms

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccination, Public Health and Epidemiology

edited by

Ricardo Izurieta

submission deadline 31 May 2026 | 9 articles | Viewed by 17719 | Submission Open

Keywords: vaccine; vaccinology; epidemiology; infectious diseases; public health; emerging infectious diseases; tropical neglected diseases

(This special issue belongs to the Section Vaccines and Public Health)

Clinical Strategies to Improve Efficacy, Effectiveness, and Safety of Vaccination in Humans

edited by

Kay Choong See

submission deadline 31 May 2026 | 10 articles | Viewed by 15280 | Submission Open

Keywords: adenovirus vaccines; immunologic adjuvants; adult; communicable diseases; geriatrics; immunocompromised Host; mRNA vaccines; pediatrics; public health; attenuated vaccines; inactivated vaccines

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

A One-Health Perspective on Immunization Against Infectious Diseases

edited by Jose Camilla Sammartino

submission deadline 31 May 2026 | 4 articles | Viewed by 7567 | Submission Open

Keywords: One-Health vaccinology; immunization; vaccine; antibody; infectious disease; emerging pathogens; climate change; sustainability

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Research on HIV/AIDS Vaccine

edited by Portia Chipo Mutevedzi and

Nagesh Kolishetti

submission deadline 31 May 2026 | 3 articles | Viewed by 7067 | Submission Open

Keywords: HIV; antiretroviral treatment (ART); vaccines; drug resistance; vaccine efficacy

(This special issue belongs to the Section HIV Vaccines)

Vaccines to Achieve Affordable Universal Coverage

edited by Pui Hong Chung

submission deadline 31 May 2026 | 2 articles | Viewed by 6377 | Submission Open

Keywords: Sustainable Development Goals (SDGs); global health; vaccines; vaccine equity; vaccine disparities; vaccine accessibility; vaccination literacy; vaccine innovation; disease prevention; vaccine policy and implementation; public health policy; health economics; healthcare disparities; universal health coverage; international health partnerships

(This special issue belongs to the Section Vaccines and Public Health)

Safety and Immunogenicity of Vaccination

edited by Jennifer Serwanga

submission deadline 31 May 2026 | 3 articles | Viewed by 2820 | Submission Open

Keywords: vaccine safety; immunogenicity profiling; correlates of protection; vaccine-induced immunity; dose optimization and adjuvants; breakthrough infections; long-term immune memory; vaccines in special populations

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Vaccine, Preventive Strategies and Antiviral Responses to Zoonotic Viruses

edited by

Wei Ye

, Shu Shen, Chen Peng and Ben Hu

submission deadline 31 May 2026 | 1 articles | Viewed by 2101 | Submission Open

Keywords: alphavirus; arenavirus; bunyavirus; coronavirus; flavivirus; filovirus; orthomyxovirus (e.g.; avian influenza virus); orthopoxvirus; paramyxovirus; rhabdovirus

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Innovative Vaccines That Modulate the Immune System to Enhance Cancer Therapy

edited by

Ruchi Roy

submission deadline 31 May 2026 | 1 articles | Viewed by 1367 | Submission Open

Keywords: cancer vaccines; CAR T cell therapy; checkpoint-inhibitors; combination therapy; tumor microenvironment; tumor-infiltrating lymphocytes

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Advances in ImmunoTherapy of Cancer

edited by Li Ye and Jiajun Fan

submission deadline 31 May 2026 | 1 articles | Viewed by 1144 | Submission Open

Keywords: cancer vaccines; neoantigen; immunotherapy; cancer microenviroment

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

SARS-CoV-2 Pathogenesis, Vaccines and Therapeutics

edited by

Hatem A. Elshabrawy

submission deadline 31 May 2026 | 1 articles | Viewed by 750 | Submission Open

Keywords: vaccine; SARS-CoV-2; COVID-19; antibodies; antivirals

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Factors Affecting and Strategies Enhancing the Willingness to Receive and Uptake of Seasonal Influenza Vaccination

edited by

Paul Shing-fong Chan

submission deadline 31 May 2026 | Viewed by 430 | Submission Open

Keywords: factors; strategies; willingness; uptake; seasonal influenza vaccination

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines Based on Dendritic Cells: Breaking Barriers to New Immune Response Approach

edited by

Soledad Lopez-Enriquez

submission deadline 31 May 2026 | Viewed by 428 | Submission Open

Keywords: plasmacytoid dendritic cells; myeloid dendritic cells; immunotolerance; regulatory T cells; cytotoxic T cells; NK cells; immunotherapies; nanovaccines; immunometabolism; delivery systems

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Therapeutic Cancer Vaccines: Advances, Challenges, and Future Directions

edited by Erminia Massarelli and Victoria M. Villaflor

submission deadline 31 May 2026 | Viewed by 422 | Submission Open

Keywords: therapeutic cancer vaccines; clinical trials; solid tumors; malignant hematology; peptide vaccines; DNA vaccines; vector vaccines; dendritic cell vaccines; allogenic vaccines; mRNA vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Recent Research on Adenovirus-Vectored Vaccines

edited by

Michael A. Barry

and

Vijay S. Reddy

submission deadline 31 May 2026 | Viewed by 290 | Submission Open

Keywords: adenovirus; replication competent; single cycle; replication defective; serotypes; targeting; structure; cryo-EM; vaccines

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Avian Viruses and the Host Immune System

edited by