Special Issue "Aptasensors"
Deadline for manuscript submissions: closed (31 October 2013)
Dr. Beate Strehlitz
Department Environmental and Biotechnology Centre, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany
Phone: 49 341 2351764
Fax: +49 341 235 1764
Interests: biosensor development and application; aptamer selection and characterization; aptamer based sensors and assays
Aptamers are a very attractive class of biologic receptor molecules being in great demand in the development of new biosensors, so-called aptasensors. Aptamers are short single-stranded DNA or RNA oligonucleotides able to bind with high affinity and specificity to their target. They are usually generated by an in vitro selection and amplification technology (SELEX). From a large oligonucleotide library with big sequence diversity and structural complexity only those oligonucleotides are selected and enriched during several selection rounds which can bind very tightly to the specific molecular target. Aptamer development and application increased in the last decades. Aptamers are favourably used in biosensors as sensitive and selective bio-receptors coupled with a variety of transducer principles such as optical, mass-sensitive and electrochemical detection. The analytes cover a wide range from small molecules, like nucleotides, cofactors, amino acids, organic molecules over peptides, polysaccharides and proteins to complex structures like whole cells, viruses and single cell organisms. Aptasensors offer great potential to measure substances in clinical diagnostics, environmental analytics, food and biotechnology industries, process engineering and others. The Special Issue will publish those full research, review and high rated manuscripts addressing the development and application of aptamer based biosensors.
Dr. Beate Strehlitz
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed Open Access monthly journal published by MDPI.
- affinity sensor
- mass sensitive
- label- and label-free detection