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Pathogens publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Parasitic Helminths and Control Strategies

edited by

Jackson Victor de Araújo

and

Luís Madeira de Carvalho

submission deadline 31 Jul 2026 | 5 articles | Viewed by 6541 | Submission Open

Keywords: control of helminthosis; biological control; vaccines; resistant breeds; diagnostics of helminths; epidemiology of helminths; chemical and phytotherapeutic anthelmintics; One Health

(This special issue belongs to the Section Parasitic Pathogens)

Natural Products Chemistry: Innovation and New Frontiers in Antiparasitic Therapies

edited by

Raymundo Alejandro Pérez Hernández

Ramiro Quintanilla-Licea

Eduardo Sánchez-García

and

Joel Horacio Elizondo Luevano

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1542 | Submission Open

Keywords: natural products; antiparasitic activity; medicinal plants; microorganisms; marine organisms; animal byproducts; in vitro; in vivo; and in silico approaches; natural products chemistry; pharmacognosy; innovative therapies; ethnopharmacology; micro-nanoparticles; targeted therapy; epidemiology; purification and extraction; ligand& ndash; receptor activity

(This special issue belongs to the Section Parasitic Pathogens)

Parasites Circulation Between the Three Domains of One Health

edited by

Gábor Nagy

and

Ágnes Csivincsik

submission deadline 31 Jul 2026 | Viewed by 362 | Submission Open

Keywords: parasites of shared habitats; anthelmintic resistance; emerging parasites; climate sensitive parasitic infections; One Health approach to parasitic diseases; livestock-health-related human-wildlife conflicts; other aspects of the livestock-wildlife interface

(This special issue belongs to the Section Parasitic Pathogens)

Viral Vectored Vaccines: From Design to Clinical Implementation for Emerging Pathogens

edited by Alina Tscherne and

Hinh Ly

submission deadline 31 Jul 2026 | Viewed by 172 | Submission Open

Keywords: preclinical testing; clinical testing; animal models; viral vector vaccines; vaccine innovation; immune response; mucosal vaccines; antigen design; zoonotic diseases; pandemic preparedness

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Structure-Based Antiviral Drug Discovery

edited by

Zhao Wang

and Boshi Huang

submission deadline 31 Jul 2026 | Viewed by 160 | Submission Open

Keywords: structure-based drug discovery; antiviral drugs; viral targets; structural biology; drug design

(This special issue belongs to the Section Viral Pathogens)

Viral Oncology and Targeted Therapies for Virus-Associated Cancers

edited by

Yonggang Pei

and Hua Zhang

submission deadline 31 Jul 2026 | Viewed by 120 | Submission Open

Keywords: viral oncoproteins; oncolytic viruses; antiviral therapy; cancer immunotherapy

(This special issue belongs to the Section Viral Pathogens)

Tumor Microbiome: A New Frontier in Cancer Therapy and Vaccines

edited by

Swati Jain

submission deadline 31 Jul 2026 | Viewed by 92 | Submission Open

Keywords: tumor microbiome; cancer therapy; microbial immunomodulation; tumor microenvironment; cancer vaccines; intra-tumoral microbes; microbiome-based therapeutics; host-microbe interactions; microbial biomarkers; immuno-oncology

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Emerging and Re-Emerging Viral Infections in Animals

edited by

Valeria Listorti

and

Andrea Laconi

submission deadline 31 Jul 2026 | Viewed by 80 | Submission Open

Keywords: emerging infections; re-emerging infections; viruses

(This special issue belongs to the Section Emerging Pathogens)

Advances in Tick Control

edited by Fábio Barbour Scott,

Yara Peluso Cid

, Thais Ribeiro Correia Azevedo and Diefrey Campos

submission deadline 31 Jul 2026 | Viewed by 45 | Submission Open

Keywords: acaricides; resistance; integrated pest management; biological control; plant-derived bioactive compounds; tick-borne diseases; host– parasite interactions; one health

(This special issue belongs to the Section Ticks)

Molecular Epidemiology and Host-Pathogen Interactions in Infectious Diseases

edited by

Gopinath Venugopal

, Srijon K. Banerjee and Gokul Raj Kathamuthu

submission deadline 31 Jul 2026 | Viewed by 39 | Submission Open

Keywords: host-pathogen interaction; infection and immunity; innate and adaptive immune responses; public health; epidemiology

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Foodborne Pathogens: Genetic Profiling, Resistance, and Risk Assessment

edited by

Branko Velebit

and Urska Jamnikar-Ciglenecki

submission deadline 31 Jul 2026 | Viewed by 34 | Submission Open

Keywords: foodborne pathogens; genetic profiling; antimicrobial resistance; whole-genome sequencing; risk assessment

Biosafety and Biosecurity in Work with Pathogens

edited by

Pavle Banović

and Bill Arndt

submission deadline 31 Jul 2026 | Viewed by 34 | Submission Open

Keywords: biosafety; biosecurity; pathogen inactivation; outbreak; risk

Infection and Immunity in Fish Models: Insights into Host Defense and Inflammation

edited by

Carla Lima

submission deadline 31 Jul 2026 | Viewed by 33 | Submission Open

Keywords: fish models; infection; immunity; host defense; inflammation

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Preclinical Models for Tackling Antimicrobial Resistance: From Bench to Translational Insights

edited by Rakel Arrazuria

submission deadline 31 Jul 2026 | Viewed by 28 | Submission Open

Keywords: antimicrobial resistance; preclinical models; animal models; translational research; host-directed therapy; phage therapy; One Health

Advances in Molecular Epidemiology and Innovative Diagnostic Strategies for Infectious Disease Control

edited by

Ko Ko

, Inn Kynn Khaing and

Zayar Phyo

submission deadline 31 Jul 2026 | Viewed by 22 | Submission Open

Keywords: elimination; eradication; surveillance; diagnostics; screening; epidemiology; pathogens; outbreaks; genomics; sequencing; CRISPR; point-of-care; modelling; innovation; preparedness

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

From Animal Health to Public Health: Eco-Epidemiological Pathways of Neglected Tropical Diseases

edited by Gina Polo

submission deadline 31 Jul 2026 | Viewed by 17 | Submission Open

Keywords: neglected tropical diseases; eco-epidemiology; climate change; vector dynamics; host– vector interactions; environmental drivers; public health; community-based research

Innovative Anti-Toxoplasma Strategies: Pharmacology and Drug Development

edited by

Chunmei Jin

submission deadline 31 Jul 2026 | Viewed by 16 | Submission Open

Keywords: Toxoplasma gondii; drug discovery; pharmacology; antiparasitic agents; drug repurposing; novel therapeutics; toxoplasmosis; pharmacokinetics; drug resistance

(This special issue belongs to the Section Parasitic Pathogens)

Advances in Fungal Pathogenesis and Antifungal Resistance

edited by Rishabh Sharma and

Katrina Ramonell

submission deadline 31 Jul 2026 | Viewed by 2 | Submission Open

Keywords: antifungal resistance; Candida albicans; Aspergillus fumigatus; cryptococcus neoformans; biofilm; antifungal tolerance; metabolic adaptation; stress-response pathways; nutrient acquisition; cell wall modulation; ergosterol biosynthesis; combination therapy

(This special issue belongs to the Section Fungal Pathogens)

Swine Infectious Diseases: Diagnostics, Pathogenesis, and Control Strategies

edited by

Luis G. Gimenez-Lirola

Jeffrey J. Zimmerman

and

Jesús Hernández

submission deadline 10 Aug 2026 | 7 articles | Viewed by 9324 | Submission Open

Keywords: swine; infectious diseases of swine; swine pathogens; diagnostics; pathogenesis; immune response; control strategies; surveillance; vaccines

Emerging and Re-Emerging Avian Influenza Viruses in Wildlife

edited by

Klaudia Chrzastek

submission deadline 10 Aug 2026 | 3 articles | Viewed by 6322 | Submission Open

Keywords: avian influenza virus; HPAIV; LPAIV; wildlife; surveillance; epidemiology; phylogenetics; next-generation sequencing

(This special issue belongs to the Section Viral Pathogens)

Pathogenic Escherichia coli: Mechanisms of Virulence, Antimicrobial Resistance and Public Health Implications

edited by

Bogdan Nowicki

submission deadline 10 Aug 2026 | 1 articles | Viewed by 2242 | Submission Open

Keywords: pathogenic Escherichia coli; virulence factors; antimicrobial resistance; gastrointestinal infections; public health

(This special issue belongs to the Section Bacterial Pathogens)

Antiviral Strategies Against Mpox

edited by Julia Tree, Amanda Horton, David Ulaeto, Isobel Stokes and Amanda Phelps

submission deadline 15 Aug 2026 | Viewed by 114 | Submission Open

Keywords: Mpox virus; antiviral; vaccine; medical countermeasure; therapeutic; public health

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Advanced Antimicrobial Agents: Combatting Multi-Drug Resistant Bacterial Infections

edited by Nachiket Vaze

submission deadline 20 Aug 2026 | 4 articles | Viewed by 10499 | Submission Open

Keywords: multi-drug resistance; antimicrobial susceptibility; nanoformulations; UV disinfection; antibiotic synergy

(This special issue belongs to the Section Bacterial Pathogens)

Coxiella burnetii: The Host Immune Response, Host-Pathogen Interaction and Pathogenesis

edited by

Guoquan Zhang

and Erin J. Van Schaik

submission deadline 20 Aug 2026 | 3 articles | Viewed by 4373 | Submission Open

Keywords: Coxiella burnetii; host immune responses; host– Coxiella interaction; vaccine development; pathogenesis

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Pathogen-Integrated Non-Coding Sequences: Regulatory Roles in Infection, Immune Response, and Disease

edited by

Xiao-Ou Zhang

submission deadline 20 Aug 2026 | Viewed by 285 | Submission Open

Keywords: non-coding sequences; pathogen genome integration; immune response; lymphocyte subpopulations; diagnostic biomarkers; tuberculosis; HPV-related cancers; cervical cancer; pathogen-associated cancers; infectious diseases

Tick-Borne Pathogens: Advanced Identification, Characterization, Transmission, and Prevalence Studies

edited by

Sara Savić

submission deadline 31 Aug 2026 | 5 articles | Viewed by 10308 | Submission Open

Keywords: ticks; tick-borne pathogens; identification; characterization; transmission; prevalence; host interactions; zoonoses

(This special issue belongs to the Section Ticks)

Pathogenesis, Epidemiology, and Control of Animal Influenza Viruses—2nd Edition

edited by Christina M. Leyson and

Silvia Carnaccini

submission deadline 31 Aug 2026 | 2 articles | Viewed by 4583 | Submission Open

Keywords: avian influenza; swine influenza; equine influenza; animal influenza; influenza epidemiology; pathogenesis; influenza vaccines; influenza phylogenetics.

(This special issue belongs to the Section Viral Pathogens)

Parasitic Diseases in Livestock: Advances in Diagnostics, Understanding and Control

edited by

César Cristiano Bassetto

and Ana Cláudia Alexandre de Albuquerque

submission deadline 31 Aug 2026 | 2 articles | Viewed by 2063 | Submission Open

Keywords: gastrointestinal nematodes; livestock; parasitic diseases; parasites; sheep; cattle; host– parasite interaction

(This special issue belongs to the Section Parasitic Pathogens)

Human Cytomegalovirus: From Molecular Pathogenesis to Therapeutic Innovations

edited by

Gaëtan Ligat

and Alexia Damour

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1172 | Submission Open

Keywords: human cytomegalovirus; therapeutic strategies and vaccines; glioblastoma; congenital infection; immunocompromised

(This special issue belongs to the Section Viral Pathogens)

HIV Reservoir Dynamics and Latency Mechanisms Under Current and Emerging Antiviral Strategies

edited by

Chen Zhang

and

Prasanta K. Dash

submission deadline 31 Aug 2026 | Viewed by 224 | Submission Open

Keywords: HIV reservoirs; HIV latency mechanisms; reservoir persistence; reservoir dynamics prediction; HIV therapies; reservoir targeting; reservoir eradication strategies; new gene-editing delivery vehicles

(This special issue belongs to the Section Viral Pathogens)

Regulation of Host Innate Immunity During Pathogens Infection

edited by

Xin Ran

submission deadline 31 Aug 2026 | Viewed by 76 | Submission Open

Keywords: pathogens; bacterial pathogens; pattern-recognition receptors; innate immune circuits; gram-negative and gram-positive infections; inflammasome activation

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Host–Microbiota Interactions in Periodontal Disease: Pathogenic Invasion, Immune Evasion, and Commensal Defense

edited by

Giancarlo A. Cuadra

and

Dominic L. Palazzolo

submission deadline 31 Aug 2026 | Viewed by 41 | Submission Open

Keywords: oral commensal streptococci; oral pathogens; oral epithelial tissues; pathogenic invasion; host defense; immune evasion; periodontal disease; external factors associated with periodontal disease; therapeutic strategies for periodontal disease

Immunopathogenesis of Influenza and Respiratory Syncytial Virus Infection

edited by

Norbert J. Roberts, Jr.

submission deadline 10 Sep 2026 | 2 articles | Viewed by 4026 | Submission Open

Keywords: influenza virus; respiratory syncytial virus; viral pathogenesis; monocytes– macrophages; lymphocytes

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Epidemiology, Diagnostics, and Therapeutics of High-Risk Human Papillomavirus (HPV) Infections

edited by Zhengchun Lu and Guang Fan

submission deadline 10 Sep 2026 | Viewed by 57 | Submission Open

Keywords: high-risk HPV; HPV-associated diseases; screening and diagnostics; HPV epidemiology; therapeutic and preventive strategies

(This special issue belongs to the Section Viral Pathogens)

Viral Infection and Antiviral Drug

edited by Hiya Lahiri and

Jochen Bodem

submission deadline 10 Sep 2026 | Viewed by 22 | Submission Open

Keywords: viral diseases; structural analysis; antivirals; artificial intelligence

(This special issue belongs to the Section Viral Pathogens)

Discovery of Novel Antiprotozoal Agents: Current Status and Future Perspectives

edited by

Klinger Antonio da Franca Rodrigues

submission deadline 15 Sep 2026 | Viewed by 22 | Submission Open

Keywords: neglected tropical diseases; drug discovery; natural products; medicinal chemistry

(This special issue belongs to the Section Parasitic Pathogens)

Pathogen–Host Interactions: Death, Defense, and Disease

edited by Hongyan Guo and Heather S. Koehler

submission deadline 20 Sep 2026 | 2 articles | Viewed by 7579 | Submission Open

Keywords: host– pathogen interaction; immune evasion; virulence factors; antimicrobial resistance; zoonosis

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Leishmania & Leishmaniasis

edited by

Maria Inês Fernandes Pimentel

and

Liliane de Fátima Antonio Oliveira

submission deadline 20 Sep 2026 | 4 articles | Viewed by 5497 | Submission Open

Keywords: leishmaniasis; visceral leishmaniasis; cutaneous leishmaniasis; mucosal leishmaniasis; mucocutaneous leishmaniasis; human visceral leishmaniasis; canine visceral leishmaniasis

(This special issue belongs to the Section Parasitic Pathogens)

Hepatitis Research: Current Trends

edited by

Wenyu Lin

submission deadline 21 Sep 2026 | Viewed by 82 | Submission Open

Keywords: hepatitis; liver disease; viral infection; antiviral therapy; vaccine development; immunopathogenesis; public health

Nosocomial Infections and Antimicrobial Resistance: Challenges and Solutions

edited by

Juan Manuel Bello-López

and

Miguel Ángel Loyola-Cruz

submission deadline 30 Sep 2026 | 4 articles | Viewed by 6712 | Submission Open

Keywords: nosocomial infections; antimicrobial resistance; molecular epidemiology; genomic surveillance; ESKAPE bacteria

(This special issue belongs to the Section Bacterial Pathogens)

Drug Resistant Pathogens: Diagnosis, Treatment, and Global Health Implications

edited by

Giuseppe Pipitone

Alberto Enrico Maraolo

and

Luigi Principe

submission deadline 30 Sep 2026 | 4 articles | Viewed by 5005 | Submission Open

Keywords: antibiotics; multi-drug-resistant microorganisms; difficult-to-treat infections

(This special issue belongs to the Section Bacterial Pathogens)

Pediatric Viral Infections: Epidemiology, Treatment, and Emerging Challenges

edited by

Maria Pokorska-Śpiewak

and Magdalena Rutkowska

submission deadline 30 Sep 2026 | 5 articles | Viewed by 4537 | Submission Open

Keywords: pediatric infectious diseases; viral infections; viral hepatitis; COVID-19; HIV; mother-to-child transmission; vaccines

(This special issue belongs to the Section Viral Pathogens)

Dairy Cattle Health: Mastitis, Milk Quality, and Antimicrobial Resistance from a One Health Perspective

edited by

Alfonso Zecconi

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2404 | Submission Open

Keywords: udder immune defenses; inflammation; milk leukocytes; mastitis control; One Health approach; immune components in milk

(This special issue belongs to the Section Bacterial Pathogens)

Advancing Vaccine Strategies and Technologies for Controlling Swine Infectious Diseases

edited by

Jishu Shi

and

Lihua Wang

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2290 | Submission Open

Keywords: autogenous vaccines; swine infectious diseases; adjuvants; diagnostics; swine veterinarian

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Emerging Viral Pathogens: Diagnosis, Treatment, and Public Health Interventions

edited by

Jasper Fuk-Woo Chan

and Vivian Huiping Shuai

submission deadline 30 Sep 2026 | 4 articles | Viewed by 2032 | Submission Open

Keywords: virus discovery; pathogenesis; antivirals; diagnostics; vaccines; public health

(This special issue belongs to the Section Emerging Pathogens)

From Gastroenteritis to Emerging Threats: One Health Surveillance of Viral Infections

edited by

Adriana Luchs

and

Natalia Coelho Couto de Azevedo Fernandes

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1880 | Submission Open

Keywords: viral gastroenteritis; pathology of viral infections; fecal-borne diseases; one Health; interspecies transmission; molecular epidemiology; zoonotic viruses; environmental surveillance; foodborne and waterborne pathogen

(This special issue belongs to the Section Viral Pathogens)

Epidemiology, Diagnosis and Clinical Management of Human Parasitic Infections—2nd Edition

edited by

Marcia Aparecida Speranca

and

Aline Diniz Cabral

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1364 | Submission Open

Keywords: parasitic infectious diseases; eco-epidemiology; diagnosis; treatment; clinical management; prevention

(This special issue belongs to the Section Parasitic Pathogens)

Vector-Borne Diseases and Transboundary Zoonoses: A One Health Perspective

edited by

Rafael Felipe da Costa Vieira

and

Richard de Campos Pacheco

submission deadline 30 Sep 2026 | 1 articles | Viewed by 582 | Submission Open

Keywords: zoonoses; one health approach; vector control; pathogen transmission; animal reservoirs; emerging infectious diseases; veterinary medicine; disease surveillance; epidemiology

Malaria: Updates on Prevention, Diagnosis, and Treatment

edited by Temi Lampejo and