Special Issue "Vitamin D: Current Issues and New Perspectives"
A special issue of Nutrients (ISSN 2072-6643).
Deadline for manuscript submissions: closed (15 November 2016).
Interests: vitamin D; calcium; bioactive food components; nutrient regulation of apoptosis; vitamin D, calcium, and bioactives in the prevention of obesity and cancer; vitamin D and cell calcium
Special Issues and Collections in MDPI journals
Special Issue in Nutrients: Vitamin D in Health and the Prevention and Treatment of Disease
This Special Issue will focus on the potential role and mechanisms of vitamin D for maintaining optimal health and preventing disease. The title, “Vitamin D: Current Issues and New Perspectives”, is intentionally broad, to be of interest to scientists working in the most promising areas of vitamin D research.
Vitamin D3, a hormone precursor and a micronutrient, is increasingly often considered important for disease prevention and maintaining good health throughout the life; however, the causality of these claims has not been mechanistically or probabilistically substantiated. The hormone 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) functions via genomic and nongenomic mechanisms in a number of cell types, and vitamin D hormonal and nutritional status has been linked to multiple diseases and disorders. For example, vitamin D deficiency and insufficiency have been associated with the increased risk of cancer, diabetes, obesity, osteoporosis, infectious and immune-mediated diseases, cardiovascular disease, etc. A promising approach for the prevention of these diseases may include maintaining the optimal vitamin D status, while specifically designed vitamin D analogs can be used to trigger vitamin D-dependent cellular responses (e.g., intracellular Ca2+ signals, apoptosis, immune response) that are mechanistically linked to the disease treatment. Understanding the role of 1,25(OH)2D3 in regulation of cellular signaling may lead to discovery of novel therapeutic and preventive modalities for various diseases. Understanding the role of vitamin D endocrine system and vitamin D nutritional and hormonal status in regulation of physiological functions may help to develop new approaches for the disease prevention and maintaining good health.
The purpose of this Special Issue is to provide an update on vitamin D mechanism and function, including novel insights on mechanisms of action of 1,25(OH)2D3 , as well as to discuss the role of and new perspectives for vitamin D in maintaining optimal health and disease prevention. The Editors of Nutrients extend an invitation to scientists to submit original research or reviews on any of the above topics for this Special Issue on vitamin D.
Prof. Dr. Igor N. Sergeev
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Vitamin D
- 1,25-Dihydroxyvitamin D
- 25-Hydroxyvitamin D
- Vitamin D endocrine system
- Vitamin D hydroxylases
- Vitamin D receptor
- Vitamin D binding protein
- Vitamin D metabolism
- Vitamin D and Ca2+ signaling
- Vitamin D status
- Vitamin D nutrition
- Vitamin D deficiency
- Vitamin D analysis methods
- Vitamin D and health
- Vitamin D and calcium
- Vitamin D and bone
- Vitamin D and muscle
- Vitamin D and intestine
- Vitamin D and reproduction
- Vitamin D and brain
- Vitamin D and physical performance
- Vitamin D and disease
- Vitamin D analogs
- Cardiovascular disease
- Infectious diseases
- Renal diseases
- Bone diseases
- Immune system diseases