Nutritional Support of GLP-1 Therapy: From Diabetes and Obesity Management to Cardiovascular Prevention
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".
Deadline for manuscript submissions: 15 August 2026 | Viewed by 47
Special Issue Editors
Interests: clinical nutrition; pharmacy; cardiovascular prevention
Interests: clinical nutrition; dietary prevention and therapy for type 2 diabetes; obesity and cardiovascular diseases; nutrition-related cardiometabolic risk; public health nutrition; dietary patterns; compliance with nutritional guidelines
Special Issue Information
Dear Colleagues,
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have rapidly evolved from glucose-lowering agents into pleiotropic drugs with benefits that extend far beyond glycaemic control. Current evidence shows that GLP-1 RAs can significantly reduce body weight, lower blood pressure, improve lipid profiles, reduce insulin resistance and provide direct cardioprotective and vasculoprotective effects. Consequently, these agents are increasingly recommended not only for the treatment of type 2 diabetes and obesity but also for the primary prevention of cardiovascular disease. The weight loss achieved through the pharmacological action of GLP-1 RAs, especially when combined with other agents, is comparable to the outcomes previously only attainable through bariatric surgery. However, these unprecedented weight-loss responses raise new concerns, including potential decreases in skeletal muscle quantity, quality and function, gastrointestinal adverse effects, risk of inadequate nutrient intake, possible reductions in bone mineral density, and relatively high discontinuation rates of treatment. Therefore, structured nutritional monitoring and personalised dietary support are crucial components of effective GLP-1 RA therapy management.
This Special Issue of Nutrients, "Nutritional Support of GLP-1 Therapy: From Diabetes and Obesity Management to Cardiovascular Prevention”, invites original research and state-of-the-art reviews that address the efficacy and safety of GLP-1-based regimens in the context of nutritional and musculoskeletal risks and propose evidence-based strategies for optimal dietary, nutritional supplementation, and lifestyle support.
Dr. Magdalena Makarewicz-Wujec
Dr. Alicja Kucharska
Dr. Edyta Czepielewska
Guest Editors
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Keywords
- GLP-1 receptor agonists
- nutritional support
- obesity treatment
- type 2 diabetes
- cardiovascular prevention
- muscle mass preservation
- bone health
- adverse effects
- weight management
- micronutrient intake
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