Special Issue "Polyunsaturated Fatty Acids Intake and Human Health"
Deadline for manuscript submissions: closed (31 July 2020).
Interests: human nutrition; nutritional biochemistry; fatty acids; in vitro digestion; bioavailability; nutrigenomics; bioactive compounds
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Dietary lipids are important for human health, providing not only caloric energy, but also taking part in vital cellular functions. While saturated (SFAs) and monounsaturated fatty acids (MUFAs) can be synthesized de novo, two polyunsaturated fatty acids (PUFAs), namely linolenic (LA) and alpha-linolenic (ALA) acid, must be obtained via dietary intake. LA and ALA are then metabolized to longer and more unsaturated n-6 and n-3 PUFAs, respectively. Since endogenous conversion is not sufficient, an adequate amount of PUFAs must be introduced with the diet.
Dietary PUFAs, especially n-3 PUFAs, are important for human health. High fat consumption and high ratios of n-6/n-3 PUFAs are associated with an increased incidence of obesity, diabetes, cardiovascular disease and cancer. Although an adequate intake has been estimated for n-6 and n-3 PUFAs, many factors contribute to the difference in response to the diet—among others, the genetic background that influences dietary lipid absorption and metabolism, the gut microenvironment, and the bioavailability of fatty acids embedded in different food matrices.
This Special Issue invites comprehensive reviews, clinical trials, epidemiological analyses, and studies employing cell and animal models that further elucidate the relationship between dietary intake of PUFAs and human health.
Prof. Dr. Alessandra Bordoni
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- Polyunsaturated fatty acids
- Dietary lipids
- Human health