Single-Dose SDA-Rich Echium Oil Increases Plasma EPA, DPAn3, and DHA Concentrations
by
Theresa Greupner 1,
Elisabeth Koch 2, Laura Kutzner 2,
Andreas Hahn 1,
Nils Helge Schebb 2 and
Jan Philipp Schuchardt 1,*
Theresa Greupner 1,
Elisabeth Koch 2, Laura Kutzner 2,
Andreas Hahn 1,
Nils Helge Schebb 2 and
Jan Philipp Schuchardt 1,*
1
Institute of Food Science and Human Nutrition, Leibniz University Hannover, 30177 Hannover, Germany
2
Chair of Food Chemistry, Faculty of Mathematics and Natural Sciences, University of Wuppertal, 42119 Wuppertal, Germany
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(10), 2346; https://doi.org/10.3390/nu11102346
Received: 12 September 2019 / Revised: 26 September 2019 / Accepted: 28 September 2019 / Published: 2 October 2019
(This article belongs to the Special Issue Polyunsaturated Fatty Acids Intake and Human Health)
The omega-3 (n3) polyunsaturated fatty acids (PUFA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are associated with health benefits. The primary dietary source of EPA and DHA is seafood. Alpha-linoleic acid (ALA) has not been shown to be a good source for EPA and DHA; however, stearidonic acid (SDA)—which is naturally contained in echium oil (EO)—may be a more promising alternative. This study was aimed at investigating the short-term n3 PUFA metabolism after the ingestion of a single dose of EO. Healthy young male subjects (n = 12) ingested a single dose of 26 g of EO after overnight fasting. Plasma fatty acid concentrations and relative amounts were determined at baseline and 2, 4, 6, 8, 24, 48, and 72 h after the ingestion of EO. During the whole examination period, the participants received standardized nutrition. Plasma ALA and SDA concentrations increased rapidly after the single dose of EO. Additionally, EPA and DPAn3 concentrations both increased significantly by 47% after 72 h compared to baseline; DHA concentrations also significantly increased by 21% after 72 h. To conclude, EO increases plasma ALA, SDA, EPA, DPAn3, and DHA concentrations and may be an alternative source for these n3 PUFAs.
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MDPI and ACS Style
Greupner, T.; Koch, E.; Kutzner, L.; Hahn, A.; Schebb, N.H.; Schuchardt, J.P. Single-Dose SDA-Rich Echium Oil Increases Plasma EPA, DPAn3, and DHA Concentrations. Nutrients 2019, 11, 2346.
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