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Nuts for Human: The Role of Nuts in a Healthy Diet

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: closed (15 May 2025) | Viewed by 4281

Special Issue Editors


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Guest Editor
Departamento de Ciências Farmacêuticas/Centro de Ciências da Saúde, Universidade Federal da Paraíba, Cidade Universitária—Campus I, Caixa Postal 5009, João Pessoa 58051-970, Brazil
Interests: redox signaling; antioxidants; cardiovascular diseases; hypertension; endothelial dysfunction; natural products; aging; pharmacy; pharmacology
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Co-Guest Editor
Health Sciences Center, Department of Pharmaceutical Sciences, Campus I, Federal University of Paraíba, João Pessoa 58059-900, PB, Brazil
Interests: natural products; nuts; cardiovascular; cardiology; aging

Special Issue Information

Dear Colleagues,

Nuts are highly nutritious and widely consumed foods that offer various health benefits, especially regarding cardiovascular health, weight management, diabetes, metabolic imbalance, and chronic disease prevention. Regular consumption of nuts has been associated with reduced risks of developing cardiovascular diseases and has been linked to a decreased risk of atherosclerosis. Nuts have shown promise in improving the metabolic profile of individuals, reducing the lipid profile and inflammation, improving endothelial function, and lowering blood pressure.

This Special Issue provides an excellent opportunity for researchers to contribute significantly to the intersection between nutritional science and cardiovascular care. We invite submissions of original research, reviews, meta-analyses, and perspective articles that address these or related topics. Submissions should aim to fill gaps in the existing literature, challenge established paradigms, or explore the biological mechanisms by which nut constituents (such as unsaturated fats, L-arginine, and plant sterols) influence endothelial function, plaque stability, and cardiac biomarkers. This field of investigation is large, and researchers from interdisciplinary fields are particularly encouraged to contribute, given the broad implications of nut consumption on health.

Prof. Dr. Isac Medeiros
Dr. Robson Cavalcante Veras
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nuts
  • cardiovascular diseases
  • diabetes
  • atherosclerosis
  • oxidative stress
  • human health

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Published Papers (2 papers)

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Research

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13 pages, 269 KiB  
Article
Nut Consumption Is Associated with Cognitive Status in Southern Italian Adults
by Justyna Godos, Francesca Giampieri, Evelyn Frias-Toral, Raynier Zambrano-Villacres, Angel Olider Rojas Vistorte, Vanessa Yélamos Torres, Maurizio Battino, Fabio Galvano, Sabrina Castellano and Giuseppe Grosso
Nutrients 2025, 17(3), 521; https://doi.org/10.3390/nu17030521 - 30 Jan 2025
Cited by 1 | Viewed by 3244
Abstract
Background: Nut consumption has been considered a potential protective factor against cognitive decline. The aim of this study was to test whether higher total and specific nut intake was associated with better cognitive status in a sample of older Italian adults. Methods: A [...] Read more.
Background: Nut consumption has been considered a potential protective factor against cognitive decline. The aim of this study was to test whether higher total and specific nut intake was associated with better cognitive status in a sample of older Italian adults. Methods: A cross-sectional analysis on 883 older adults (>50 y) was conducted. A 110-item food frequency questionnaire was used to collect information on the consumption of various types of nuts. The Short Portable Mental Status Questionnaire was used to assess cognitive status. Multivariate logistic regression analyses were performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between nut intake and cognitive status after adjusting for potential confounding factors. Results: The median intake of total nuts was 11.7 g/day and served as a cut-off to categorize low and high consumers (mean intake 4.3 g/day vs. 39.7 g/day, respectively). Higher total nut intake was significantly associated with a lower prevalence of impaired cognitive status among older individuals (OR = 0.35, CI 95%: 0.15, 0.84) after adjusting for potential confounding factors. Notably, this association remained significant after additional adjustment for adherence to the Mediterranean dietary pattern as an indicator of diet quality, (OR = 0.32, CI 95%: 0.13, 0.77). No significant associations were found between cognitive status and specific types of nuts. Conclusions: Habitual nut intake is associated with better cognitive status in older adults. Full article
(This article belongs to the Special Issue Nuts for Human: The Role of Nuts in a Healthy Diet)

Other

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29 pages, 3436 KiB  
Systematic Review
Are Nuts Safe in Diverticulosis? A Mixed-Methods Systematic Review of Available Evidence
by Constantinos Voniatis, Timea Csupor and Attila Szijártó
Nutrients 2025, 17(13), 2122; https://doi.org/10.3390/nu17132122 - 26 Jun 2025
Viewed by 530
Abstract
Background: Diverticulosis is defined as the presence of diverticula in the intestinal tract. While asymptomatic in most cases, severe complications can arise. The precise etiology of diverticulosis is still being investigated, but its correlation to dietary exposures has been proven. While certain diet [...] Read more.
Background: Diverticulosis is defined as the presence of diverticula in the intestinal tract. While asymptomatic in most cases, severe complications can arise. The precise etiology of diverticulosis is still being investigated, but its correlation to dietary exposures has been proven. While certain diet recommendations have cemented themselves throughout the years, others seem to be always disputed. Nut consumption has been highly questioned among researchers and clinicians alike for decades. Objectives: This review aims to examine all available data regarding nut consumption and diverticulosis. Methods: We performed a systematic literature review from various databases (PubMed, Web of Science, Embase, and the Cochrane Library). We followed a multi-modal approach, incorporating both qualitative and quantitative techniques to assess and evaluate studies that investigated nut exposure and diverticulosis. Results: Nine observational studies encompassing over two million person-years were included. The qualitative synthesis and risk-of-bias assessments align with a neutral to modestly protective effect of moderate nut intake. Analysis of nut-specific cohorts revealed no significant increase in diverticulitis risk (HR 0.89, 95% CI 0.71–1.12). A sensitivity analysis including a prudent dietary pattern yielded a significant risk reduction (HR 0.75, 0.58–0.97). Dose–response modelling indicated a linear 5% reduction in risk per additional weekly serving. Robustness checks (leave-one-out analysis, tripping point analysis, etc.) confirmed the stability of these findings, with no single study unduly influencing the pooled estimates. Conclusions: Although limitations are present, current evidence suggests that moderate nut consumption is safe and may be protective against diverticulosis, while showing no adverse effect on diverticulitis incidence. Full article
(This article belongs to the Special Issue Nuts for Human: The Role of Nuts in a Healthy Diet)
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