Investigating the Impact of Diet on Neuroimmune Regulation in Multiple Sclerosis

Dear Colleagues,

For this Special Issue, we invite high-quality contributions that explore the intricate and multifaceted relationship between diet, nutrition, and multiple sclerosis (MS). Emerging evidence highlights that dietary interventions may significantly influence not only the onset and progression of MS but also the neuroinflammatory and immune processes underlying the disease. We welcome original research articles, systematic reviews, and clinical studies that examine how specific nutrients, dietary patterns, and metabolic factors can modulate disease activity, symptom burden, and therapeutic response.

A particular emphasis will be placed on studies investigating the roles of vitamins, micronutrients, and bioactive compounds in neuroprotection and immune regulation, as well as research exploring the gut–brain axis and the impact of diet-induced changes in the microbiome on MS outcomes.

Submissions addressing molecular mechanisms linking diet to demyelination, oxidative stress, and neurodegeneration are especially encouraged, alongside interdisciplinary approaches combining nutritional science, immunology, and neurology.

Through this Special Issue, we aim to advance the scientific understanding of nutrition as a potential preventive and adjunctive therapeutic strategy in MS, fostering new insights that bridge experimental research and clinical application.

Prof. Dr. Diego Fresegna
Guest Editor

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