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Neuroprotective Roles of Dietary Bioactive Compounds

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Neuro Sciences".

Deadline for manuscript submissions: 20 March 2026 | Viewed by 51

Special Issue Editors


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Guest Editor
School of Health and Medical Sciences, University of Southern Queensland, Toowoomba, QLD 4350, Australia
Interests: cerebrovascular function; cognition; brain structure and function; cardiometabolic disease; chronic diseases; biomarkers; gut–brain axis; inflammation; oxidative stress; ageing; cardiorespiratory risk factors
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Curtin Medical Research Institute, Curtin University, Perth, WA, Australia
2. Perron Institute for Neurological and Translational Science, Perth, WA, Australia
Interests: micro-nutrients; cognitive performance; brain function; vitamin D
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
School of Health and Medical Sciences, University of Southern Queensland, Toowoomba, QLD 4350, Australia
Interests: exercise physiology; clinical exercise physiology; rehabilitation; respiratory muscles; cerebrovascular function
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Dietary bioactive compounds are increasingly being recognised for their multifaceted neuroprotective properties, offering promising avenues for preventing and managing a wide spectrum of neurodegenerative, neurovascular, and neuroinflammatory conditions. These compounds, such as polyphenols, including flavonoids, carotenoids, and omega-3 fatty acids, exert beneficial effects through antioxidant, anti-inflammatory, endothelial-modulating, and neurodegenerative mechanisms. Emerging evidence suggests they may enhance cerebrovascular function, including cerebral haemodynamics, which is essential in sustaining cognitive performance and reducing neurological risk.

For this Special Issue, we invite original research articles and reviews exploring the mechanistic, clinical, and translational roles of dietary bioactives in supporting brain health. We welcome studies addressing bioavailability, gut–brain axis interactions, and the modulation of key risk factors such as oxidative stress, cerebrovascular dysfunction, metabolic and hormonal imbalances, neuroimmune activation, and mitochondrial decline. Contributions that integrate nutritional strategies into lifestyle or pharmacological interventions to enhance neuroprotection and resilience are particularly encouraged.

We look forward to receiving papers that advance our understanding of how nutrition-based strategies can complement pharmacological approaches and inform public health recommendations to ensure lifelong neurovascular and cognitive health.

Kind regards,

Dr. Edward Bliss
Dr. Virginie Lam
Dr. Dean E. Mills
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neuroprotection
  • dietary bioactive compounds
  • cerebrovascular function
  • cognition
  • polyphenols
  • flavonoids
  • neuroinflammation
  • cardiometabolic diseases
  • gut–brain axis
  • brain structure and function
  • ageing
  • neurodegeneration

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Published Papers

This special issue is now open for submission.
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