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Special Issue "Diet and Chronic Inflammation: Implication for Disease Prevention, Treatment and Healthy Lifespan"
A special issue of Nutrients (ISSN 2072-6643).
Deadline for manuscript submissions: closed (30 June 2019).
Prof. Dr. Camillo Ricordi Website E-Mail
Diabetes Research Institute and Cell Transplant Program, University of Miami Miller School of Medicine, 1450 NW 10th Avenue, Miami, Florida 33136, USA
Interests: Mediterranean diet, anti-inflammatory nutrition, autoimmunity, diabetes, Omega 3, Vitamin D3, prevention of age-related chronic degenerative diseases, healthspan medicine
Diet-induced chronic inflammation is emerging as a significant factor that can affect the incidence and progression of many degenerative conditions, including obesity, diabetes, cardiovascular, osteoarticular, neurodegenerative, autoimmune disease conditions, and cancer, to name a few. The lifespan of humans has been increasing in recent decades, but not necessarily a healthy lifespan (healthspan). We are facing an increased incidence of chronic diseases, with projections that today, for the first time, new generations of children may be the first ones to have a shorter lifespan compared to their parents’ generations. Over 95% of Americans over 65 are affected by at least one chronic degenerative condition, with substantial implications not only on their healthspan, but also on health economics, with an increased cost of healthcare which has now reached $3 trillion, or approximately 18% of the US GDP.
A diet-induced inflammatory component is now recognized in an increasing number of chronic diseases. Nutritional and lifestyle intervention could have the most profound impact on disease prevention and on halting disease progression, modifying pro-inflammatory factors that can alter hormonal signaling and modulate the innate immune system. There is a critically important and timely need to improve our knowledge on how nutrients could impact disease susceptibility and progression, including but not limited to dietary fatty acids, polyphenols, antioxidants, vitamin D, highly refined and high glycemic index food products, and animal-derived food products from different animal feed practices.
A better understanding of the relationships between diet, nutrients, inflammation, and chronic disease risk/progression will allow us to develop improved diets to modulate inflammation, offering a cost-effective, nonpharmacological approach to prevent and treat chronic disease conditions. Bioactive dietary components and supplements could represent an effective complement to healthy diets and may be of assistance in affecting inflammatory pathways that can result in epigenetic changes, such as those associated with the activation of Nuclear Factor-kB, and the resulting activation of master switches and their associated inflammatory pathways.
Prof. Camillo Ricordi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.