Effects of Natural Compounds on Various Inflammatory Diseases
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".
Deadline for manuscript submissions: 25 October 2025 | Viewed by 108
Special Issue Editor
Interests: nutraceuticals; natural products and medicinal chemistry; oxidative stress and inflammation; cancer therapeutics; molecular pharmacology; signal transduction pathways
Special Issue Information
Dear Colleagues,
This Special Issue aims to explore the potential of bioactive nutrients and nutraceuticals in managing and treating inflammatory disorders, addressing their mechanisms of action, therapeutic applications, and clinical relevance. Inflammation, while being a pivotal response to injury, infection, or stress, can lead to chronic diseases such as autoimmune disorders, cancer, cardiovascular diseases, and neuroinflammation when dysregulated. The scope of the current Special Issue includes the following topics:
- Mechanistic studies of anti-inflammatory bioactive nutrients and nutraceuticals through modulating key inflammatory pathways such as COX-2/PG, NF-κB, MAPK, JAK/STAT, TLR, NLRP3 inflammasomes, and cytokine release.
- Chronic inflammatory disorders including rheumatoid arthritis (RA), inflammatory bowel diseases (IBDs), systemic lupus erythematosus (SLE), psoriasis, chronic obstructive pulmonary disease (COPD), multiple sclerosis (MS), atherosclerosis, inflammation-driven cancers, and neurological inflammation.
- Phytochemical–drug combinations and their role in oxidative stress, apoptosis, and inflammation.
- Transilational research towards developing bioactive nutrients and nutraceuticals-based anti-inflammatory preparations, including preclinical and clinical studies, formulations, and delivery systems.
This Special Issue invites contributions ranging from original research, reviews, and clinical trials that focus on the therapeutic potential of nutraceuticals for inflammatory disorders. By bridging the gap between bioactive nutrients and translational pharmacology, the findings in this Special Issue will offer new insights into how to effectively manage various inflammation-related conditions.
Dr. Hassan Y. Ebrahim
Guest Editor
Manuscript Submission Information
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Keywords
- bioactive nutrients
- nutraceuticals
- inflammatory disorders
- inflammasomes
- oxidative stress
- reactive oxygen species (ROS)
- inflammatory cytokines
- immune modulation
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