nutrients-logo

Journal Browser

Journal Browser

The Impact of Diet on Cancer Progression and Clinical Outcomes

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 25 June 2025 | Viewed by 544

Special Issue Editors


E-Mail Website
Guest Editor
Department of Medical Physiology, Faculty of Medicine, University of Granada, 18001 Granada, Spain
Interests: metabolism; exercise; nutrition; cardiovacular disease; cancer
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Co-Guest Editor
Department of Medical Physiology, Faculty of Medicine, University of Granada, 18001 Granada, Spain
Interests: metabolism; cancer; aging; clinical nutrition

Special Issue Information

Dear Colleagues,

The global incidence of cancer has been rising steadily, posing significant challenges to healthcare systems worldwide. Among the myriad factors influencing cancer development and progression, diet plays a pivotal role in modulating tumor biology and determining clinical outcomes. Nutritional interventions hold promise for influencing tumor growth, metabolism, and immune responses, thereby presenting potential strategies for cancer prevention, management, and survivorship. However, the specific dietary approaches that yield effective outcomes remain an area of active research and debate.

This Special Issue seeks to compile cutting-edge research on the role of dietary interventions in cancer biology, metabolic reprogramming, and the enhancement of patient quality of life. We invite submissions of original research articles, systematic reviews, meta-analyses, and narrative reviews that explore the relationships between dietary patterns, nutrients, and cancer prevention or treatment. Studies on personalized nutrition in oncology are particularly welcome.

Prof. Dr. Francisco José Amaro-Gahete
Guest Editor

Dr. Juan Luis López-Cánovas
Co-Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutritional intervention
  • cancer
  • metabolism
  • personalized nutrition
  • cancer prevention
  • cancer biology
  • diet

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Other

17 pages, 2083 KiB  
Systematic Review
Association of Dietary Advanced Glycation End Products with Overall and Site-Specific Cancer Risk and Mortality: A Systematic Review and Meta-Analysis
by Carlos Pascual-Morena, Miriam Garrido-Miguel, Irene Martínez-García, Maribel Lucerón-Lucas-Torres, Eva Rodríguez-Gutiérrez, Carlos Berlanga-Macías, Jaime Fernández-Bravo-Rodrigo and Silvana Patiño-Cardona
Nutrients 2025, 17(10), 1638; https://doi.org/10.3390/nu17101638 - 10 May 2025
Viewed by 298
Abstract
Background/Objectives: Dietary advanced glycation end products (dAGEs) have a pro-inflammatory effect and increase oxidative stress, potentially leading to cancer. The aim of this study was to estimate the association between dAGEs consumption and risk and mortality from overall cancer and according to [...] Read more.
Background/Objectives: Dietary advanced glycation end products (dAGEs) have a pro-inflammatory effect and increase oxidative stress, potentially leading to cancer. The aim of this study was to estimate the association between dAGEs consumption and risk and mortality from overall cancer and according to its site. Methods: A systematic search was conducted in Medline, Scopus, Web of Science, and the Cochrane Library from inception to April 2025. The search strategy was conducted according to the PECO structure adapted to this study, as well as the inclusion criteria, in which the population (P) was the adult population, the exposure (E) was the highest level of dAGEs intake, the comparator (C) was the lowest level of dAGEs intake, and the outcomes (O) were the overall cancer risk, cancer risk by site, and cancer mortality. Results across studies were summarised using random effects and fixed effects. Results: Fourteen studies were included in the systematic review. In the random-effects meta-analysis, high dAGEs intake was associated with Hazard Ratio (HR) = 0.99 [95% Confidence Interval (95% CI): 0.98, 1.00] for overall cancer risk. However, although there was no association with breast cancer (BC), there was an association with invasive BC, with HR = 1.14 (95% CI: 1.05, 1.23). In contrast, in other tumours, there were opposite results depending on the site of the cancer. Conclusions: The reduction in cancer risk is not clinically significant. However, high consumption of dAGEs may increase the risk of BC, particularly the invasive BC, which is a challenge for cancer prevention and subsequent mortality. Due to the limited evidence, further studies are needed to confirm the potential impact of dAGEs, as well as other dietary factors that may play a larger role in cancer development. Full article
(This article belongs to the Special Issue The Impact of Diet on Cancer Progression and Clinical Outcomes)
Show Figures

Figure 1

Back to TopTop