Nutritional Supplementation in CKD: Indications, Timing, and Strategies
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".
Deadline for manuscript submissions: 25 November 2025 | Viewed by 4
Special Issue Editor
Interests: nutritional status; inflammation body composition; chronic kidney disease; parenteral nutrition
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
There is a high prevalence of protein-energy wasting (PEW) in patients with advanced chronic kidney disease (CKD) prior to the initiation of dialysis, a condition that may further deteriorate with the commencement of renal replacement therapy.
A fundamental aspect of the nephro-nutritional approach is the continuous monitoring of nutritional status. The primary objective is to prevent the onset of malnutrition; however, when prevention is not feasible, early diagnosis becomes essential. Prompt intervention—through oral, enteral, or parenteral supplementation—should be implemented before PEW progresses to an irreversible stage, at which point nutritional interventions may no longer be effective.
Given that the incidence of CKD increases with age, the nutritional management of these patients must also consider age-related physiological changes that contribute to a higher risk of malnutrition.
Nutritional supplementation strategies range from reinforcing individualized dietary advice and increasing the intake of specific nutrients to the use of oral nutritional supplements. In selected cases, enteral nutrition—although infrequently employed in renal patients—may be indicated. Intradialytic parenteral nutrition (IDPN) also constitutes a viable supplementary option, particularly in patients undergoing hemodialysis.
This Special Issue will address the indications for nutritional supplementation in CKD, outlining the appropriate timing, formulation, and delivery methods needed to optimize clinical outcomes in this vulnerable population.
Prof. Dr. Guillermina Barril
Guest Editor
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Keywords
- advanced chronic kidney disease
- oral supplement
- Intradialytic parenteral nutrition (IDPN)
- protein-energy wasting (PEW)
- dietary advice
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