Diet, Nutrition and Pediatric Metabolic Liver Diseases (PMLD)
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Pediatric Nutrition".
Deadline for manuscript submissions: 15 May 2026
Special Issue Editors
Interests: Pediatric; etabolic liver diseases; gastrointestinal diseases; nutrition; diet; genetics; microbiota; gut-liver-axis
Interests: liver diseases; metabolic dysfunction-associated steatotic liver disease; hepatocellular carcinoma; epigenetic mechanisms; microRNAs, nutrigenomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Pediatric metabolic liver diseases (PMLD), such as metabolic dysfunction-associated steatotic liver disease (MASLD), inherited metabolic disorders (e.g., Wilson’s disease and glycogen storage diseases), and other hepatometabolic conditions, represent a growing global health concern. Emerging evidence highlights the pivotal role of diet and nutrition in both the pathogenesis and management of these conditions during childhood and adolescence.
This Special Issue of Nutrients, “Diet, Nutrition and Pediatric Metabolic Liver Diseases (PMLD)”, aims to gather cutting-edge research and expert reviews on the complex interplay between diet, nutritional status, and metabolic liver health in the pediatric setting or experimental models. We welcome original contributions and reviews that explore mechanistic insights, clinical interventions, nutritional strategies, epidemiological trends, and translational approaches related to PMLD.
Topics of interest include, but are not limited to, the following:
- Nutritional factors involved in the development and progression of pediatric MASLD;
- The role of dietary patterns (e.g., Mediterranean, low-carbohydrate, ketogenic) in PMLD management;
- Nutrigenomics and metabolomics approaches in pediatric liver diseases;
- The impact of early-life nutrition, maternal diet, and breastfeeding on liver development and metabolic risk;
- Micronutrient deficiencies and their hepatic consequences in pediatric patients;
- Dietary interventions in inborn errors of metabolism affecting the liver;
- Gut-liver axis and microbiota-targeted nutritional therapies;
- Clinical trials and real-world evidence on diet-based therapies in pediatric hepatology;
- Public health and preventive strategies for nutrition-related liver diseases in children.
This Special Issue encourages interdisciplinary research from the fields of nutrition, pediatrics, hepatology, gastroenterology, metabolic medicine, genetics, and public health. Our goal is to foster a comprehensive understanding of how tailored nutritional strategies can improve outcomes in children with metabolic liver disorders.
Dr. Nicoleta Gimiga
Dr. Anna Alisi
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Metabolic diseases,
- children,
- gut-liver-axis,
- early-life nutrition,
- diet,
- nutrigenomics,
- metabolomics,
- inborn errors of metabolism,
- public health
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