Potential Benefits of Dietary Fat in Chronic Diseases
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".
Deadline for manuscript submissions: closed (20 November 2023) | Viewed by 6285
Special Issue Editors
Interests: cardiovascular medicine; nutrition; disease prevention; systems biology; personalized medicine; biomarker discovery; digital health; wellness
Interests: molecular biology; biochemistry; bioinformatics; insulin resistance; diabetes; malnutrition; metabolism; metabolic syndrome; fat; metabolic diseases
Special Issue Information
Dear Colleagues,
Optimal cardiovascular health and its correlates are rare, making cardiometabolic and cardiovascular diseases among the leading causes of disability and death worldwide. There is thus a pressing need to find non-pharmacological means of prevention and treatment to increase the quality of life of individuals and to lower the pressures on health systems and societies.
Beneficial dietary fatty acids have been regarded as potent preventive and curative means of chronic diseases ever since their presence was observed as one of the cornerstones of the traditional Mediterranean diet, and since epidemiological studies have underlined their association with health and longevity.
However, discordant findings from trials using purified forms of beneficial fats such as long-chain mono or polyunsaturated fats for the treatment of dyslipidemia have created confusion in the field, which might have hindered their use in preventive and curative settings.
Many interesting questions still need to be addressed in order to clear up any doubts.
For instance, what is the direct causative role of circulating beneficial fats? Could they merely be surrogates of healthy eating habits and lifestyles or of protective cultural and geographical (genetic) parameters? Should purified, high-dose supplementation be preferred over whole food sources that include potentially beneficial components of food matrices? What is the targeted EPA to the DHA ratio, and what is the role of the less studied DPA intermediate? Is there inter-individual variability in response to dietary fats and, if so, how can this variability impact future dietary recommendations and treatment strategies? What are the most appropriate exposure biomarkers, treatment timing, and clinical populations to maximize outcomes?
These topics represent just a few lines of thought helping to guide this Special Issue in order to ultimately clarify and provide new insights into the potential benefits of dietary fat in optimizing health and prevent chronic diseases. All original contributions, including epidemiological or observational studies, systematic reviews and meta-analyses, and editorials, are welcome.
Dr. Sébastien Lacroix
Dr. Juan De toro Martin
Guest Editors
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Keywords
- cardiovascular disease
- cardioprotective
- dyslipidemia
- anti-inflammatory
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