Optimizing Nutrient Intake in Celiac Disease: A Focus on Dietary Interventions

Dear Colleagues,

Celiac disease (CD) is an immune-mediated enteropathy triggered by gluten ingestion in genetically susceptible individuals. Although the gluten-free diet (GFD) remains the cornerstone of treatment, recent evidence shows that achieving optimal nutritional status and dietary balance is not always guaranteed by strict gluten withdrawal. Micronutrient deficiencies, altered body composition, changes in gut microbiota, and metabolic imbalances can persist despite adherence to a GFD, highlighting the need for improved dietary guidance and optimization of the gluten-free diet itself.

This Special Issue, titled “Optimizing Nutrient Intake in Celiac Disease: A Focus on Dietary Interventions”, aims to explore the multifaceted relationship between nutrition and CD. We welcome contributions addressing dietary optimization, nutrient supplementation, and nutritional assessment tools, as well as studies evaluating the challenges and barriers patients face when implementing a GFD in real-world settings.

Submissions focusing on omics-based approaches—such as metabolomics, proteomics, and microbiome analyses—related to nutrient absorption, metabolism, or diet–host interactions in celiac disease are particularly encouraged. By integrating clinical, nutritional, and molecular insights, this Special Issue seeks to provide a comprehensive and translational view of how diet influences disease course, metabolic recovery, and long-term health outcomes in CD.

Original research articles, clinical trials, meta-analyses, and comprehensive reviews making novel contributions to this evolving field are welcome. In addition, we particularly encourage submissions presenting practical dietary interventions or strategies that can be directly applied in clinical or community settings, aiming to improve patient outcomes and quality of life.

Dr. Rafael Martín-Masot
Dr. Víctor Manuel Navas-López
Guest Editors

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