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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Food Fraud, Adulteration, and Contamination: Challenges, Detection Strategies, and Prevention
edited by
submission deadline 31 Dec 2026 | 2 articles | Viewed by 650 | Submission Open
Keywords: food safety; food quality; food adulteration; sample preparation; emerging food contaminants; quality monitoring; mass spectrometry; chromatography; food authentication; trace analysis; analytical methods
(This special issue belongs to the Section Food Chemistry)
Optical Functional Materials: Design, Synthesis and Applications
edited by Tamara Potlog and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 642 | Submission Open
Keywords: optical; design; synthesis; application; material; physical; structural; inorganic; organic; hybrid; solid-state laser; thin film; nonlinear; mechanistic; optimization
(This special issue belongs to the Section Materials Chemistry)
MOF-Based Catalysts for CO2 Capture and Conversion
edited by Ning Liu and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 623 | Submission Open
Keywords: metal–organic frameworks (MOFs); CO2 capture and conversion; heterogeneous catalysis; sustainable catalysis; porous materials; green chemistry; structure–activity relationship; carbon utilization
(This special issue belongs to the Section Materials Chemistry)
Applied Analytical Chemistry: Third Edition submission deadline 31 Dec 2026 | 1 articles | Viewed by 593 | Submission Open
Keywords: food production; forensic practice and archaeology; environmental monitoring; clinical practice; quality control in industry; analysis of plant material
(This special issue belongs to the Section Analytical Chemistry)
Recent Advances of Biochar in Wastewater Treatment submission deadline 31 Dec 2026 | 1 articles | Viewed by 584 | Submission Open
Keywords: biochar; wastewater treatment; adsorption; hybrid treatment; sorbent; catalyst; composite; heavy metals; nutrients; pharmaceuticals; circular economy; life cycle assessment
(This special issue belongs to the Section Applied Chemistry)
Challenges in Green Analytical Chemistry submission deadline 31 Dec 2026 | Viewed by 563 | Submission Open
Keywords: green analytical chemistry; sustainable analytical methods; eco-friendly sample preparation; miniaturized techniques; solvent reduction; greenness assessment tools; waste minimization; renewable analytical materials; energy-efficient analysis; green metrics in chemistry
Tautomerism and Proton Transfer—Fundamental Aspects and Applicability
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 560 | Submission Open
Keywords: tautomerism; proton transfer; hydrogen bonding; molecular switches; molecular sensors; dye chemistry; organic synthesis; solvent effect; photo-, halo-, and thermochromism; molecular spectroscopy; computational chemistry; photochemistry
(This special issue belongs to the Section Physical Chemistry)
Exclusive Contributions by the Editorial Board Members (EBMs) of the Organic Chemistry Section of Molecules, 2nd Edition
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 538 | Submission Open
Keywords: organic compounds; organic synthesis; organic reaction; click chemistry; organocatalysis
(This special issue belongs to the Section Organic Chemistry)
Beyond Convention: Novel Sources, Strategies, and Technologies for Researching Fungal Bioactives submission deadline 31 Dec 2026 | Viewed by 530 | Submission Open
Keywords: fungal bioactives; genome mining; metagenomics; synthetic biology; AI-driven discovery; structure elucidation; extremophilic fungi; drug discovery pipelines
Light-Driven Organic Chemistry: Synthesis, Mechanisms, and Photochemical Applications
edited by and Fernando Heering Bartoloni
submission deadline 31 Dec 2026 | 1 articles | Viewed by 509 | Submission Open
Keywords: organic photochemistry; light-driven synthesis; photocatalysis; excited-state chemistry; photophysical properties; mechanistic investigations; photoresponsive molecules
(This special issue belongs to the Section Photochemistry)
Chemistry of Amino Acids, Peptides, and Proteins
edited by and Nicholas Truex
submission deadline 31 Dec 2026 | Viewed by 505 | Submission Open
Keywords: amino acids; peptides; proteins; synthesis; derivatives; characterization; structural studies; biophysical properties; natural products
(This special issue belongs to the Section Macromolecular Chemistry)
Cyclodextrin Chemistry and Toxicology, 4th Edition
edited by and Gianluca D’Abrosca
submission deadline 31 Dec 2026 | 1 articles | Viewed by 501 | Submission Open
Keywords: inclusion complexes; cyclodextrin derivates; biological activities of cyclodextrin; pharmacology and pharmacokinetics of cyclodextrin; industrial applications of cyclodextrins; nano-materials and nano-structured coatings containing cyclodextrins; environmental remediation of cyclodextrins; toxicity of cyclodextrin inclusion complexes
(This special issue belongs to the Section Applied Chemistry)
New Insights into Porous Carbon Materials for a Sustainable Future
edited by
submission deadline 31 Dec 2026 | Viewed by 483 | Submission Open
Keywords: porous carbon materials; biomass-derived carbon; waste-to-carbon; energy storage; carbon capture; supercapacitors; green synthesis; functionalized carbon; environmental applications
Food Chemistry and Bioactive Compounds in Relation to Health, 3rd Edition submission deadline 31 Dec 2026 | 1 articles | Viewed by 478 | Submission Open
Keywords: biologically active compounds; functional food ingredients; metabolic pathways; health benefits; foodborne pathogens; probiotics; chromatographic analysis; enzymes applied in the food industry
(This special issue belongs to the Section Food Chemistry)
Advanced Materials for Efficient Sulfur Removal in Industrial and Environmental Applications
edited by and Tendai O. Dembaremba
submission deadline 31 Dec 2026 | Viewed by 471 | Submission Open
Keywords: industrial desulfurization; catalytic sulfur removal; nanostructured catalysts; hydrodesulfurization (HDS); environmental catalysis; SOx emission control; clean fuel production; process scalability
Bioactive Molecules in Sustainable Food Packaging: From Natural Sources to Functional Materials
edited by Mia Kurek
submission deadline 31 Dec 2026 | 1 articles | Viewed by 454 | Submission Open
Keywords: functional food packaging materials; controlled release; stability of active compounds; scalability
(This special issue belongs to the Section Materials Chemistry)
Functional Carbon Materials from Biomass for Environmental Applications
edited by
submission deadline 31 Dec 2026 | Viewed by 447 | Submission Open
Keywords: biomass-derived carbon; functional carbon materials; activated carbon; biochar; porous carbon; surface functionalization; structure-property relationships; biomass valorization; circular economy; environmental remediation; water treatment; adsorption and catalysis; electrocatalysis; green synthesis; sustainable materials
(This special issue belongs to the Section Materials Chemistry)
Chromatographic Methods for Monitoring Food Safety and Quality—Second Edition submission deadline 31 Dec 2026 | Viewed by 445 | Submission Open
Keywords: antibiotics; bioactive compounds; chromatography; contaminants; food chemistry; food authentication; food quality; food safety; method validation; microplastics; pesticides; veterinary drugs
(This special issue belongs to the Section Analytical Chemistry)
Chemical Design of Nanocomposite Materials for Enhanced Electrochemical Performance
edited by and Xingxing Jiao
submission deadline 31 Dec 2026 | Viewed by 441 | Submission Open
Keywords: nanocomposite materials; electrochemical properties; lithium batteries; solid-state electrolytes; interfacial electrochemistry; ionic conductivity; electrode design; theoretical calculations
(This special issue belongs to the Section Electrochemistry)
Next-Generation Electrochemical Sensors for a Sustainable Future submission deadline 31 Dec 2026 | 1 articles | Viewed by 430 | Submission Open
Keywords: electrochemical sensors; next-generation sensors; sustainable materials; novel materials; sustainable applications
(This special issue belongs to the Section Electrochemistry)
Advances in Anticancer Activity of Natural Compounds: New Findings and Potential Applications
edited by , and Melissa García-Carrasco
submission deadline 31 Dec 2026 | Viewed by 427 | Submission Open
Keywords: cancer; natural compound; drug discovery; bioactive compounds; encapsulation technology; molecular mechanisms; translational oncology; therapeutic applications
(This special issue belongs to the Section Natural Products Chemistry)
Exploring Bioactive Polyphenolic Compounds in Food and Natural Real-World Samples, 3rd Edition
edited by and Katia Arena
submission deadline 31 Dec 2026 | Viewed by 417 | Submission Open
Keywords: polyphenols; foods; natural products; comprehensive two-dimensional liquid chromatography
(This special issue belongs to the Section Natural Products Chemistry)
Molecular Spectroscopy and Molecular Structure
edited by , and Yukihiro Ozaki
submission deadline 31 Dec 2026 | Viewed by 410 | Submission Open
Keywords: molecular spectroscopy; molecular structure; applications in biological sciences; applications in materials science; molecular interaction; hydrogen bonds; methodological development; quantum chemical calculation
(This special issue belongs to the Section Photochemistry)
Catalysis for Drug Discovery
edited by
submission deadline 31 Dec 2026 | Viewed by 410 | Submission Open
Keywords: organic synthesis; metal catalysis; organocatalysis; asymmetric catalysis; photocatalysis; electrocatalysis; drug discovery
(This special issue belongs to the Section Organic Chemistry)
Computational Chemistry in Homogeneous and Heterogeneous Catalysis and Surface Chemistry
edited by Haya Kornweitz and
submission deadline 31 Dec 2026 | Viewed by 401 | Submission Open
Keywords: density functional theory (DFT); heterogeneous catalysis; homogeneous catalysis; surface reactions; reaction mechanism; metallic Surfaces; nanoparticles; adsorption; desorption; ab initio calculations; material science; surface modelling; reaction kinetics; thermochemistry and reactivity; transition State theory; potential energy surfaces (PES); hydrogenation; hydrogen evolution reaction (HER); oxygen evolution reaction (OER); CO2 reduction; electrocatalysis; machine learning
New Dereplication Approaches for Targeting Bioactive Metabolites from Natural Products submission deadline 31 Dec 2026 | Viewed by 394 | Submission Open
Keywords: natural products; natural sources; bioactive metabolites; dereplication; LC‑MS/MS; chromatographic techniques; NMR spectroscopy; metabolomics; molecular networking; spectral libraries; in silico tools; bioactivity‑guided isolation; antioxidant activity; anti‑inflammatory activity; antimicrobial activity; anticancer activity
(This special issue belongs to the Section Natural Products Chemistry)
Exploring the Modification of Nanocellulose: Strategies for Enhancing Properties and Expanding Applications submission deadline 31 Dec 2026 | Viewed by 376 | Submission Open
Keywords: nanocellulose; cellulose-polymer composites; cellulose nanofibers (CNFs); cellulose nanocrystals (CNCs); cellulose processing; nanocellulose functionalization; TEMPO cellulose; surface modification; grafting; nanocellulose biosensors
(This special issue belongs to the Section Macromolecular Chemistry)
Bioactive and Nutritional Molecules: From Natural Sources to Therapeutic and Health Applications, 2nd Edition
edited by
submission deadline 31 Dec 2026 | Viewed by 367 | Submission Open
Keywords: bioactive and nutritional molecules; natural therapeutic agents; bioactive compounds
(This special issue belongs to the Section Cross-Field Chemistry)
Benefits, Properties and Innovative Uses of Flavonoids submission deadline 31 Dec 2026 | Viewed by 367 | Submission Open
Keywords: flavonoids; polyphenols; cocrystals; bioactive compounds; antioxidant activity; health benefits; functional foods; nutraceuticals; solubility; bioavailability
(This special issue belongs to the Section Natural Products Chemistry)
Design, Synthesis, and Biological Evaluation of Novel Metal Complexes submission deadline 31 Dec 2026 | Viewed by 358 | Submission Open
Keywords: coordination compound; 3d metal complexes; biological activity; anticancer activity; selectivity; toxicity; antioxidant activity; antibacterial activity; mechanism of action
(This special issue belongs to the Section Medicinal Chemistry)
Plant-Derived Natural Products: Isolation, Structural Characterization, and Bioactivities
edited by Felipe Moura Araújo da Silva, and
submission deadline 31 Dec 2026 | Viewed by 325 | Submission Open
Keywords: phytochemistry; medicinal plants; nuclear magnetic resonance (NMR); LC-MS; GC-MS; plant metabolomics; untargeted metabolomics; bioactivity-guided fractionation; pharmacological evaluation; pharmacognosy
(This special issue belongs to the Section Natural Products Chemistry)
Computational Chemistry of Non-Covalent and Coordination Interactions submission deadline 31 Dec 2026 | Viewed by 323 | Submission Open
Keywords: noncovalent interactions; coordination compounds; hydrogen bonds; metal complexes; stacking interactions; π-interactions; computational chemistry; density functional theory
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Advances in Biomass Conversion, Biofuel Production and Biorefinery Processes submission deadline 31 Dec 2026 | Viewed by 320 | Submission Open
Keywords: biomass conversion; biofuels; catalysis; biorefinery integration; CO2 utilization; hydrogen production; energy storage; life-cycle and techno-economic analysis
(This special issue belongs to the Section Green Chemistry)
From Discovery to Delivery: Novel Anticancer Molecules and Advanced Targeting Strategies
edited by
submission deadline 31 Dec 2026 | Viewed by 315 | Submission Open
Keywords: anticancer drug discovery; targeted drug delivery; nanocarriers; tumor-targeting ligands; controlled release
(This special issue belongs to the Section Medicinal Chemistry)
Bioactive Phytochemicals as Antioxidant Agents submission deadline 31 Dec 2026 | Viewed by 314 | Submission Open
Keywords: natural-based bioactive compounds; phytochemicals; antioxidants; biological activity; additives; adjuvants, nutraceuticals; food products; pharmaceutical products
(This special issue belongs to the Section Natural Products Chemistry)
Chemometrics and Machine Learning in Forensic Chemistry
edited by Eugenio Alladio
submission deadline 31 Dec 2026 | Viewed by 307 | Submission Open
Keywords: chemometrics; machine learning; forensic chemistry; forensic toxicology; multivariate analysis; spectroscopy; imaging; evidence evaluation; classification
(This special issue belongs to the Section Analytical Chemistry)
Coordination Compounds: Synthesis, Structural Characterization and Versatile Biological Applications
edited by
submission deadline 31 Dec 2026 | Viewed by 304 | Submission Open
Keywords: coordination compounds; essential/non-essential metal ions; biological activity; antitumor; antimicrobial; in vitro assays; carrier; inorganic/organic matrix
(This special issue belongs to the Section Inorganic Chemistry)
New Synthetic Drugs of Abuse submission deadline 31 Dec 2026 | Viewed by 297 | Submission Open
Keywords: new psychoactive substances (NPS); structure–activity relationships; pharmacokinetics and pharmacodynamics; toxicological mechanisms; advanced analytical methodologies; biomarkers of exposure
(This special issue belongs to the Section Medicinal Chemistry)
Current Advances in Biodegradable Polymers
edited by Aurelio Ramírez-Hernández and Alejandro Aparicio-Saguilán
submission deadline 31 Dec 2026 | Viewed by 297 | Submission Open
Keywords: natural and synthetic polymers; biodegradation; synthesis; characterization; composites; nanomaterials; processing; environmental impact; molecular modeling
(This special issue belongs to the Section Materials Chemistry)
Isolation and Functions of Bioactive Peptides in Food
edited by Noé Ontiveros and Oscar Gerardo Figueroa Salcido
submission deadline 31 Dec 2026 | Viewed by 289 | Submission Open
Keywords: bioactive peptides; protein hydrolysates; functional foods; nutraceuticals; disease prevention; therapy; delivery; in silico
(This special issue belongs to the Section Food Chemistry)
Advances in Functional Materials for Heterogeneous Electrocatalysis
edited by
submission deadline 31 Dec 2026 | Viewed by 289 | Submission Open
Keywords: interfacial interactions; environmental sustainability; energy conversion; water remediation; in situ characterization; first-principles calculations; machine learning
(This special issue belongs to the Section Electrochemistry)
Stimuli-Responsive Molecular Crystals: From Structure to Function
edited by
submission deadline 31 Dec 2026 | Viewed by 288 | Submission Open
Keywords: stimuli-responsive molecular crystals; thermosalient and photosalient effects; supramolecular chemistry and crystal engineering; molecular design and polymorphism; anisotropic thermal expansion and molecular packing effects; solid-state phase transitions; crystallography under external stimuli; structure–property relationships in molecular solids; computational chemistry of molecular crystals
(This special issue belongs to the Section Materials Chemistry)
Advanced Analytical Strategies and Innovative Processing Technologies for Food Quality and Safety submission deadline 31 Dec 2026 | Viewed by 283 | Submission Open
Keywords: food quality and safety assurance; innovative food processing (HPP, PEF, Cold Plasma, etc.); pesticide residue analysis and mitigation; food contaminants; non-targeted analysis (NTA); food contact materials and NIAS analysis; food fingerprinting and authenticity; personalized nutrition and bioactive stability; AI and chemometric modeling in food science; advanced mass spectrometry (UPLC-MS/MS, GC-HRMS)
(This special issue belongs to the Section Food Chemistry)
Chemical Characterization and Anti-Inflammatory/Antinociceptive Activities of Extracts from Medicinal Plants submission deadline 31 Dec 2026 | Viewed by 283 | Submission Open
Keywords: medicinal plants; phytochemistry; plant extracts; chemical characterization; bioactive compounds; anti-inflammatory activity; antinociceptive activity; natural products
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Small Bioactive Molecules: From Molecular Pathways to Health Benefits submission deadline 31 Dec 2026 | Viewed by 278 | Submission Open
Keywords: small bioactive molecules; nutraceuticals; functional foods; disease prevention; diet–health interactions; signal transduction pathways
(This special issue belongs to the Section Medicinal Chemistry)
Synthesis of Innovative and Smart Materials for Batteries
edited by and Kangyu Zou
submission deadline 31 Dec 2026 | Viewed by 271 | Submission Open
Keywords: batteries; energy storage; electrodes; materials design; smart functional components
(This special issue belongs to the Section Materials Chemistry)
Bioactive Compounds in Plant-Derived Extracellular Vesicles and Their Biomedical Applications
edited by
submission deadline 31 Dec 2026 | Viewed by 269 | Submission Open
Keywords: plant-derived extracellular vesicles; nanomedicine; nanomaterials; biological characteristics; bioactive compounds; biomedical applications; drug delivery
(This special issue belongs to the Section Natural Products Chemistry)
Novel Micro- and Nanocomposites as Ionizing Radiation Shielding Materials: From the Concept to Real-Life Protection
edited by
submission deadline 31 Dec 2026 | Viewed by 267 | Submission Open
Keywords: nanocomposites; microcomposites; shielding; radiation; ionizing radiation
(This special issue belongs to the Section Materials Chemistry)
Essential Oils in Food Safety and Human Health: Bioactive Phytochemistry, Mechanisms of Action, and Applications submission deadline 31 Dec 2026 | Viewed by 266 | Submission Open
Keywords: essential oil bioactivity; structure–activity relationships; food safety and preservation; antimicrobial resistance; nanoemulsions; encapsulation; functional foods; nutraceuticals; mechanisms of action; bioavailability and bioaccessibility; active food packaging; in silico molecular docking
(This special issue belongs to the Section Natural Products Chemistry)
Fluorescent Organic Molecules: Design, Properties, and Applications
edited by Minghao Hu
submission deadline 31 Dec 2026 | Viewed by 266 | Submission Open
Keywords: fluorescent organic molecules; molecular design; photophysical properties; bioimaging; chemical sensing; biomedical applications
(This special issue belongs to the Section Photochemistry)
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