Special Issue "Focusing on Sulfur in Medicinal Chemistry"
Deadline for manuscript submissions: closed (30 April 2018)
Prof. Dr. Thierry Besson
Normandie Univ, Univ Rouen; INSA Rouen, CNRS, Laboratoire COBRA UMR6014Bâtiment IRCOF, 1 rue Tesnière, F-76821 Mont Saint-Aignan Cedex, France
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Interests: N,O,S-heterocycles for therapeutic applications; microwave-assisted chemistry; active drugs for cancer and central nervous system; cancer and CNS drugs
The presence of heterocycles in all kinds of organic compounds of interest in biology, pharmacology and medicine, is well known. Among them, sulphur-containing heterocyclic compounds have maintained the interest of researchers, and their unique structures have led to several applications in different areas; especially in the design of drugs. The presence of heteroatoms results in significant changes in the cyclic molecular structure and the number of synthetic methods to afford sulphur-containing molecules is, in practice, restricted to the availability of the appropriate sulphur reagent. Sometimes, the preparation of theses heterocyclic systems by conventional ways is a hard work that implies many synthetic steps and extensive starting material. For all these reasons, the various possibilities offered by innovative technologies are particularly attractive. This Special Issue aims to review recent developments in the synthesis of bioactive sulphur-containing heteroaromatic compounds under conditions that may include the application of new technology or techniques (e.g., microwave irradiation, flow chemistry) in the ring-forming step.
Prof. Dr. Thierry Besson
Manuscript Submission Information
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