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Topical Collection "Early-Career Researchers in Chemistry"

Editors

Prof. Dr. Antonella Curulli
E-Mail Website
Guest Editor
Consiglio Nazionale delle Ricerche (CNR) Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), Italy
Interests: organic electrochemistry and electrosynthesis; sensors and biosensors fabrication; Built Heritage
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Prof. Dr. Eugenio Aprea
E-Mail Website
Guest Editor
Center Agriculture Food Environment, University of Trento/Fondazione Edmund Mach, Via E. Mach, 1 - 38010 S.Michele all'Adige (TN), Italy
Interests: gas chromatography; mass spectrometry; physical and chemical properties of food and relationship with human sensory perception; sensory analysis
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Prof. Dr. Francesca Cardona
E-Mail Website
Guest Editor
Dipartimento di Chimica "Ugo Schiff", Università degli Studi di Firenze, Via della Lastruccia 3-13, 50019 Sesto Fiorentino (Firenze), Italy
Interests: synthetic organic chemistry; carbohydrate-based glycomimetics; glycosidase inhibitors; iminosugar synthesis; Lysosomal Storage diseases; Gaucher disease; Parkinson disease
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Prof. Dr. Ioanna Chinou
E-Mail Website
Guest Editor
Department of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece
Interests: bee keeping products (propolis, honeys, royal jelly, pollen); pyrrolizidine alkaloids; regulatory issues on herbal medicines (EMA, NCAs); phenolics; herbals for veterinary use
Prof. Dr. James Gauld
E-Mail Website
Guest Editor
Prof. Dr. Lakshmi Kotra
E-Mail Website
Guest Editor
Leslie Dan Faculty of Pharmacy, University of Toronto, and Krembil Research Institute, University Health Network, Toronto, ON, Canada
Interests: drug discovery; medicinal chemistry; cannabinoids; nucleosides; clinical and translational research
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Prof. Dr. Maurizio Peruzzini
E-Mail Website
Guest Editor
Consiglio Nazionale delle Ricerche (CNR) Istituto di Chimica dei Composti OrganoMetallici (ICCOM), Via Madonna del Piano 10, 50019 Sesto Fiorentino (FI), Italy
Interests: activation and functionalization of elemental phosphorus; activation of small inorganic and organic molecules; transition-metal hydrides and molecular hydrogen chemistry; materials for H-storage; carbon dioxide capture and valorization
Special Issues, Collections and Topics in MDPI journals

Topical Collection Information

Dear Colleagues,

As the guest editors of a timely, topical and high-quality collection titled “Early-Career Researchers in Chemistry” in Molecules, we are delighted to announce this exciting initiative, and we are particularly encouraging “Early-Career Researchers” in all areas of chemistry around the world to take part. This collection will bring together the latest high-quality contributions from early-career researchers in chemistry actively working in all fields of chemistry at the early stages of their careers (i.e. within the first 5 years of their independent career).

We invite submissions of original research and review articles from early-career researchers that explore contemporary issues in all fields of Chemistry for inclusion in this topical collection of Molecules. A preliminary review of the submissions by the editors will be conducted to assess suitability, after which the peer review process will begin.

This initiative is designed to increase the visibility and reputation of early-career researchers in the chemical research community with a focus on quality, innovation and breakthrough research.

Prof. Dr. Antonella Curulli
Prof. Dr. Eugenio Aprea
Prof. Dr. Francesca Cardona
Prof. Dr. Ioanna Chinou
Prof. Dr. James Gauld
Prof. Dr. Lakshmi Kotra
Prof. Dr. Maurizio Peruzzini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (2 papers)

2021

Article
Development of Chitosan-Based Surfaces to Prevent Single- and Dual-Species Biofilms of Staphylococcus aureus and Pseudomonas aeruginosa
Molecules 2021, 26(14), 4378; https://doi.org/10.3390/molecules26144378 - 20 Jul 2021
Cited by 1 | Viewed by 886
Abstract
Implantable medical devices (IMDs) are susceptible to microbial adhesion and biofilm formation, which lead to several clinical complications, including the occurrence of implant-associated infections. Polylactic acid (PLA) and its composites are currently used for the construction of IMDs. In addition, chitosan (CS) is [...] Read more.
Implantable medical devices (IMDs) are susceptible to microbial adhesion and biofilm formation, which lead to several clinical complications, including the occurrence of implant-associated infections. Polylactic acid (PLA) and its composites are currently used for the construction of IMDs. In addition, chitosan (CS) is a natural polymer that has been widely used in the medical field due to its antimicrobial and antibiofilm properties, which can be dependent on molecular weight (Mw). The present study aims to evaluate the performance of CS-based surfaces of different Mw to inhibit bacterial biofilm formation. For this purpose, CS-based surfaces were produced by dip-coating and the presence of CS and its derivatives onto PLA films, as well surface homogeneity were confirmed by contact angle measurements, Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The antimicrobial activity of the functionalized surfaces was evaluated against single- and dual-species biofilms of Staphylococcus aureus and Pseudomonas aeruginosa. Chitosan-based surfaces were able to inhibit the development of single- and dual-species biofilms by reducing the number of total, viable, culturable, and viable but nonculturable cells up to 79%, 90%, 81%, and 96%, respectively, being their activity dependent on chitosan Mw. The effect of CS-based surfaces on the inhibition of biofilm formation was corroborated by biofilm structure analysis using confocal laser scanning microscopy (CLSM), which revealed a decrease in the biovolume and thickness of the biofilm formed on CS-based surfaces compared to PLA. Overall, these results support the potential of low Mw CS for coating polymeric devices such as IMDs where the two bacteria tested are common colonizers and reduce their biofilm formation. Full article
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Graphical abstract

Article
A Bibliometric Evaluation of the Top 100 Cited Dimethyl Fumarate Articles
Molecules 2021, 26(4), 1085; https://doi.org/10.3390/molecules26041085 - 19 Feb 2021
Viewed by 954
Abstract
Dimethyl fumarate is a cytoprotective and immunomodulatory drug used in the treatment of multiple sclerosis. We performed a bibliometric study examining the characteristics and trends of the top 100 cited articles that include dimethyl fumarate in the title. On 21 September 2020 we [...] Read more.
Dimethyl fumarate is a cytoprotective and immunomodulatory drug used in the treatment of multiple sclerosis. We performed a bibliometric study examining the characteristics and trends of the top 100 cited articles that include dimethyl fumarate in the title. On 21 September 2020 we carried out an electronic search in the Web of Science (WOS), seeking articles that include the following terms within the title: dimethyl fumarate, BG-12, or Tecfidera. To focus our investigation on original research, we refined the search to include only articles, early access, others, case report, and clinical trials. We obtained a total of 1115 items, which were cited 7169 times, had a citation density of 6.43 citations/item, and an h-index of 40. Around 2010, there was a jump in the number of published articles per year, rising from 5 articles/year up to 12 articles/year. We sorted all the items by the number of citations and selected the top 100 most cited (T100). The T100 had 4164 citations, with a density of 37 citations/year and contained 16 classic research articles. They were published between 1961 and 2018; the years 2010–2018 amassed nearly 80% of the T100. We noted 17 research areas with articles in the T100. Of these, the number one ranking went to neurosciences/neurology with 39 articles, and chemistry ranked second on the T100 list with 14 items. We noticed that the percentage of articles belonging to different journals changed depending on the time period. Chemistry held the highest number of papers during 1961–2000, while pharmacology andneurosciences/neurology led the 2001–2018 interval. A total of 478 authors from 145 institutions and 25 countries were included in the T100 ranking. The paper by Gold R et al. was the most successful with 14 articles, 1.823 citations and a density of 140.23 citations/year. The biotechnological company Biogen led the T100 list with 20 articles. With 59 published articles, the USA was the leading country in publications. We concluded that this study analyzed the use of and research on dimethyl fumarate from a different perspective, which will allow the readership (expert or not) to understand the relevance of classic and recent literature on this topic. Full article
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