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Marine Bioactive Peptides—Structure, Function and Application, 3rd Edition

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 497

Special Issue Editors


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Guest Editor
National and Provincial Joint Laboratory of Exploration and Utilization of Marine Aquatic Genetic Resources, National Engineering Research Center of Marine Facilities Aquaculture, School of Marine Science and Technology, Zhejiang Ocean University, Zhoushan 316022, China
Interests: marine peptides; structure identification; structure–function relationship; antioxidant activity; cytoprotection; Nrf2 pathway; non-alcoholic fatty liver disease (NAFLD); angiotensin-I-converting enzyme (ACE)-inhibitory; hypolipidemic activities; hypotensive activity; neuropeptides; cephalopods; neuroendocrine immune regulation; reproductive regulation
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan, China
Interests: marine peptides; structure identification; structure–function relationship; antioxidant activity; cytoprotection; Nrf2 pathway; non-alcoholic fatty liver disease (NAFLD); angiotensin-I-converting enzyme (ACE)-inhibitory; hypolipidemic activities; hypotensive activity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, peptides generated from various marine organisms have attracted wide attention due to their diverse chemical structures and bioactivities, including antioxidants, immune modulation, angiotensin-I-converting enzyme (ACE) inhibition, hypotensive, hypolipidemic, antiviral, cytotoxic, neurotoxic, anticoagulant, antifreeze, etc. Moreover, bioactive peptides can serve as additional functional components used in health foods, nutraceuticals, biopreservatives, cosmetics, and pharmaceuticals.

Given the widespread and current interest in this topic, we decided to propose Version 3.0 of this Special Issue with the aim of collecting papers on up-to-date information regarding the preparation, structural identification, activity, functional evaluation, and application of marine bioactive peptides.

We look forward to receiving your contributions.

Prof. Dr. Chang-Feng Chi
Prof. Dr. Bin Wang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • marine peptides
  • protein hydrolysate
  • biotechnological production
  • structure identification
  • structural modification
  • bioactivity and function
  • structure–function relationship
  • bioavailability
  • nutritional value
  • functional foods
  • application

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Published Papers (1 paper)

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Review

23 pages, 846 KiB  
Review
Multifaceted Marine Peptides and Their Therapeutic Potential
by Svetlana V. Guryanova and Tatiana V. Ovchinnikova
Mar. Drugs 2025, 23(7), 288; https://doi.org/10.3390/md23070288 - 15 Jul 2025
Viewed by 332
Abstract
Marine peptides, derived from a great number of aquatic organisms, exhibit a broad spectrum of biological activities that hold a significant therapeutic potential. This article reviews the multifaceted roles of marine peptides, focusing on their antibacterial, antibiofilm, antifungal, antiviral, antiparasitic, cytotoxic, anticancer, immunomodulatory, [...] Read more.
Marine peptides, derived from a great number of aquatic organisms, exhibit a broad spectrum of biological activities that hold a significant therapeutic potential. This article reviews the multifaceted roles of marine peptides, focusing on their antibacterial, antibiofilm, antifungal, antiviral, antiparasitic, cytotoxic, anticancer, immunomodulatory, chemotactic, opsonizing, anti-inflammatory, antiaging, skin-protective, and wound-healing properties. By elucidating mechanisms of their action and highlighting key research findings, this review aims to provide a comprehensive understanding of possible therapeutic applications of marine peptides, underscoring their importance in developing novel drugs as well as in cosmetology, food industry, aquatic and agriculture biotechnology. Further investigations are essential to harness their therapeutic potential and should focus on detailed mechanism studies, large-scale production, and clinical evaluations with a view to confirm their efficacy and safety and translate these findings into practical applications. It is also important to investigate the potential synergistic effects of marine peptide combinations with existing medicines to enhance their efficacy. Challenges include the sustainable sourcing of marine peptides, and therefore an environmental impact of harvesting marine organisms must be considered as well. Full article
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