Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Translational Neuro-Oncology: Molecular Insights, Bioinformatics, and Technological Innovations
edited by Felix Mircea Brehar
submission deadline 20 Sep 2026 | Viewed by 66 | Submission Open
Keywords: translational neuro-oncology; central nervous system tumors; molecular and cellular mechanisms; multi-omics and biomarkers; bioinformatics and systems biology; artificial intelligence in medicine; radiomics and radiogenomics; precision neurosurgery; experimental and clinical research; therapeutic innovation in neuro-oncology
(This special issue belongs to the Section Physiology and Pathology)
Imaging and Analysis of Microbial Motility: From Single Cells to Communities
edited by
submission deadline 20 Sep 2026 | Viewed by 20 | Submission Open
Keywords: motility; cell tracking; biofilm; swimming; swarming; Archaea; flagella
(This special issue belongs to the Section Microbiology)
Molecular Underpinnings of Cancer: Pathways to Targeted Therapy submission deadline 30 Sep 2026 | Viewed by 91 | Submission Open
Keywords: signaling pathways; tumor microenvironment; cancer metabolism; biomarkers; drug resistance; precision medicine; targeted therapy
(This special issue belongs to the Section Medical Research)
Women's Health and Well-Being: A Focus on Obstetrics and Gynecologic Medicine
edited by Luca Roncati
submission deadline 30 Sep 2026 | Viewed by 88 | Submission Open
Keywords: women’ s health; gynecology; gynecopathology; preventive gynecological oncology; senology; breast cancer; cervical cancer; sexually transmitted infections; human papillomavirus; autoimmune diseases
(This special issue belongs to the Section Medical Research)
Biomarkers in Ischemic Stroke: From Discovery to Clinical Applications
edited by Hock-Kean Liew
submission deadline 30 Sep 2026 | Viewed by 86 | Submission Open
Keywords: ischemic stroke; biomarkers; neuroinflammation; oxidative stress; excitotoxicity; thrombolysis; mechanical thrombectomy; blood– brain barrier; neuroprotection; precision medicine
(This special issue belongs to the Section Medical Research)
Neurorehabilitation: Technology-Driven Recovery and Functional Rewiring
edited by
submission deadline 30 Sep 2026 | Viewed by 84 | Submission Open
Keywords: cognitive-motor recovery; neuroplasticity; multidimensional assessment; post-stroke rehabilitation
(This special issue belongs to the Section Medical Research)
Cognitive and Imaging Mechanisms in Neurological Disorders
edited by Foteini Christidi, and
submission deadline 30 Sep 2026 | Viewed by 76 | Submission Open
Keywords: neurological disorders; cognitive dysfunction; neuropsychological assessment; neuroimaging; structural MRI; functional MRI; multimodal neuroimaing; biomarkers; machine learning in neurology; neurorehabilitation
(This special issue belongs to the Section Medical Research)
Ocular Diseases: Mechanisms, Diagnostics, and Emerging Therapeutic Strategies
edited by Joanna Dolar-Szczasny
submission deadline 30 Sep 2026 | Viewed by 48 | Submission Open
Keywords: molecular mechanisms of eye disease; oxidative stress and inflammation; neurodegeneration in vision; ocular biomarkers; pharmacological therapies; gene therapy; stem cell and regenerative approaches; precision/personalized ophthalmology
(This special issue belongs to the Section Medical Research)
Advanced Optical Imaging for Tissue and Tumour Characterization
edited by and Ana Teresa A. Amaral
submission deadline 30 Sep 2026 | Viewed by 48 | Submission Open
Keywords: optical imaging; label-free imaging; functional imaging; multimodal imaging; tissue characterization; tumour microenvironment; tumour heterogeneity; extracellular matrix; therapeutic monitoring
(This special issue belongs to the Section Medical Research)
The Oral-Systemic Link in Chronic Mucosal Diseases
edited by
submission deadline 30 Sep 2026 | Viewed by 26 | Submission Open
Keywords: oral diseases; general diseases; biomarkers
(This special issue belongs to the Section Medical Research)
Pathology, Diagnosis, and Treatments of Airway Diseases submission deadline 1 Oct 2026 | 1 articles | Viewed by 758 | Submission Open
Keywords: airway diseases; COPD; asthma; cystic fibrosis; bronchiectasis; biomarkers; biologics; targeted; immunology; pathogenesis
(This special issue belongs to the Section Medical Research)
Innovations in Critical Care and Anesthesiology
edited by
submission deadline 2 Oct 2026 | 1 articles | Viewed by 122 | Submission Open
Keywords: artificial intelligence in ICU; point-of-care monitoring; enhanced recovery protocols; precision anesthesia; mechanical ventilation; organ support systems; perioperative medicine; critical care innovations
(This special issue belongs to the Section Medical Research)
Artificial Intelligence in Head and Neck Cancer Radiotherapy and Imaging
edited by Elias Liolis
submission deadline 30 Oct 2026 | Viewed by 40 | Submission Open
Keywords: head and neck cancer; treatment planning; radiotherapy; oral cavity cancer; PET-CT imaging
(This special issue belongs to the Section Medical Research)
Pharmacotherapy in Critical Care: Clinical Insight and Emerging Strategy
edited by
submission deadline 31 Oct 2026 | Viewed by 86 | Submission Open
Keywords: sepsis; multidrug resistance; extracorporeal treatments; intracranial hypertension; immunomodulation; organ support; precision medicine; intensive care pharmacology
(This special issue belongs to the Section Medical Research)
Precision Approaches in Solid Tumor Oncology: From Molecular Pathways to Therapy Response
edited by and Luís Ortega-Medina
submission deadline 31 Oct 2026 | Viewed by 39 | Submission Open
Keywords: biomarkers; histology; immunohistochemistry; solid tumors; precision oncology; therapy response
(This special issue belongs to the Section Medical Research)
Otolaryngology and Sleep Medicine: From Precision Diagnosis to Advanced Therapeutics
edited by
submission deadline 28 Nov 2026 | Viewed by 32 | Submission Open
Keywords: sleep-disordered breathing; otolaryngology; sleep medicine; pulmonology; neurology
(This special issue belongs to the Section Medical Research)
Global Health in a Changing Climate: Interdisciplinary Perspectives on Human Well-Being
edited by Giuseppe Marano, , Gianandrea Traversi, and Esmeralda Capristo
submission deadline 30 Nov 2026 | Viewed by 39 | Submission Open
Keywords: climate change; global health; mental health; physical health; lifestyle interventions; cross-disciplinary research
(This special issue belongs to the Section Medical Research)
Advances in Diagnostic Management of Cardiovascular Diseases
edited by Carlo Gaudio, and
submission deadline 30 Nov 2026 | Viewed by 33 | Submission Open
Keywords: cardiovascular diagnostics; advanced imaging; biomarkers; artificial intelligence; risk stratification
(This special issue belongs to the Section Medical Research)
The 15th Anniversary of Life—New Trends in Animal Health Science
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 418 | Submission Open
Keywords: animal health science; animal disease; veterinary; animal nutrition; genetics; breeding and reproduction; One Health
(This special issue belongs to the Section Animal Science)
The Microbiome and Dysbiosis in Various Pathologies submission deadline 31 Dec 2026 | Viewed by 85 | Submission Open
Keywords: metabolic diseases (obesity; type 2 diabetes; insulin resistance; metabolic syndrome; etc.); cardiovascular diseases (atherosclerosis; hypertension; etc.); dermatological diseases (acne; eczema; psoriasis; rosacea); autoimmune and inflammatory diseases (rheumatoid arthritis; systemic lupus erythematosus; multiple sclerosis; Hashimoto’ s thyroiditis; etc.); digestive disorders (irritable bowel syndrome; inflammatory bowel disease: Crohn’ s disease and ulcerative colitis; celiac disease; lactose intolerance and other food intolerances; gastritis; helicobacter pylori infections; etc.); neurological and psychiatric disorders (Parkinson’ s and Alzheimer’ s disease; depression; anxiety; autism); recurrent infections and low immunity; cancer (colorectal; gastric; esophageal; hepatic; pancreatic; breast; pulmonary; etc.); biochemical; genetic and epigenetic biomarkers; computational analysis
(This special issue belongs to the Section Microbiology)
Pathogenesis, Biomarkers, and Treatments of Skin Diseases submission deadline 31 Dec 2026 | Viewed by 72 | Submission Open
Keywords: immune-pathogenesis; biomarkers; skin
(This special issue belongs to the Section Medical Research)
Cell Regulation and Function
edited by
submission deadline 31 Dec 2026 | Viewed by 51 | Submission Open
Keywords: cellular regulation; signal transduction; cell differentiation and apoptosis; systems biology and omicsdisease mechanisms
(This special issue belongs to the Section Cell Biology and Tissue Engineering)
Physical Activity, Inflammation, and Adipocytokines: Molecular Responses in Health and Disease
edited by and Aurora Daniele
submission deadline 31 Dec 2026 | Viewed by 39 | Submission Open
Keywords: physical activity; inflammation; inflammatory biomarkers; adipocytokines; exercise physiology; healthy life-style; metabolic disorders; cancer; athletes
(This special issue belongs to the Section Physiology and Pathology)
Targeting Myeloid Cells in the Tumor Microenvironment
edited by Tatiana I. Novobrantseva, Igor Feldman and Siamon Gordon
submission deadline 31 Dec 2026 | Submission Open
Keywords: macrophage; tolerance; repolarization; TME; cancer; immuno-therapy therapeutics immunity
(This special issue belongs to the Section Medical Research)
Ophthalmologic Diseases: From Molecules and Molecular Mechanisms to Therapeutics
edited by and
submission deadline 30 Jun 2027 | Viewed by 67 | Submission Open
Keywords: retinal disease; corneal disease; genetic diseases; inflammatory diseases; ocular diseases; ocular drug development
(This special issue belongs to the Section Physiology and Pathology)
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