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Most Cited

  • Review
  • Open Access
4 Citations
1,754 Views
35 Pages

Non-Coding RNAs in Health and Disease: From Biomarkers to Therapeutic Targets

  • Marios A. Diamantopoulos,
  • Michaela A. Boti,
  • Triantafyllia Sarri and
  • Andreas Scorilas

17 September 2025

Non-coding RNAs (ncRNAs) are critical regulators of gene expression, taking part in the modulation of multiple biological functions across a range of cell types. Initially dismissed as transcriptional noise, ncRNAs are now recognized for their signif...

  • Article
  • Open Access
4 Citations
1,422 Views
13 Pages

Objective: This study employed advanced biostatistical methods to investigate Interleukin-6 (IL-6), Tumour Necrosis Factor Alpha (TNF-α), and Myeloperoxidase (MPO) levels in serum and plasma samples from patients with severe osteoarthritis (OA)...

  • Article
  • Open Access
1 Citations
1,662 Views
11 Pages

11 July 2025

Rapid, safe, and field-deployable molecular diagnostics are crucial for the effective management of infectious disease outbreaks, particularly those involving highly infectious pathogens, which can produce clinical symptoms similar to less infectious...

  • Article
  • Open Access
1 Citations
1,861 Views
14 Pages

Validation of AIA-360 for Determination of Presepsin: A Useful Tool for the Diagnosis of Sepsis at the Emergency Department

  • Alfredo Giovannelli,
  • Massimo Pieri,
  • Eleonora Nicolai,
  • Martina Pelagalli,
  • Cinzia Calabrese,
  • Flaminia Tomassetti,
  • Jacopo Maria Legramante,
  • Alessandro Terrinoni,
  • Sergio Bernardini and
  • Marilena Minieri

25 December 2024

Sepsis is a life-threatening condition, and clinicians should diagnose it as soon as possible to enable rapid intervention. The study aims to validate the AIA-360 Presepsin (PSEP) test for its use in determination in the diagnosis of septic patients...

  • Article
  • Open Access
1 Citations
2,846 Views
11 Pages

Molecular Detection of SARS-CoV-2 Viral Particles in Exhaled Breath Condensate via Engineered Face Masks

  • Hannes Dörfler,
  • John Daniels,
  • Shekhar Wadekar,
  • Quentin Pagneux,
  • Dennis Ladage,
  • Georg Greiner,
  • Ojan Assadian,
  • Rabah Boukherroub and
  • Sabine Szunerits

12 November 2024

In this study, we present a novel face mask engineered for the collection of exhaled breath condensate (EBC) and its application and performance in a clinical study of COVID-19 infection status assessment versus the gold standard polymerase chain rea...

  • Article
  • Open Access
1 Citations
4,480 Views
12 Pages

Impact of Tube Additives on Baseline Cell-Free DNA, Blood Nuclease Activity, and Cell-Free DNA Degradation in Serum and Plasma Samples: A Comparative Study

  • Gustavo Barcelos Barra,
  • Ticiane Henriques Santa Rita,
  • Rafael Henriques Jácomo and
  • Lídia Freire Abdalla Nery

3 March 2025

Cell-free DNA (cfDNA) analysis is a pivotal tool in non-invasive diagnostics, including cancer monitoring and prenatal testing. However, the preanalytical phase, particularly the choice of anticoagulant, significantly impacts cfDNA integrity and yiel...

  • Article
  • Open Access
1 Citations
5,073 Views
9 Pages

14 March 2025

The objective of this study was to assess the performance characteristics of the new automated haematology analyser from Sysmex Corporation, the Sysmex XR-Series, compare its performance to the Sysmex XN-Series through method comparison, and compare...

  • Article
  • Open Access
1 Citations
3,091 Views
10 Pages

18 November 2024

Anticoagulants can complicate the interpretation of routine and specialised coagulation assays. Several methodologies have been developed to minimise or eliminate anticoagulant-associated interferences; however, no ‘universal methodology’...

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LabMed - ISSN 2813-9038