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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Thyroid Disorders: New Clinical Diagnosis and Management

edited by

Ioannis P. Iakovou

Rodis D. Paparodis

and

Nicholaos G. Angelopoulos

submission deadline 15 May 2026 | Viewed by 984 | Submission Open

Keywords: thyroid disorders; clinical diagnosis; ultrasound; elastography; thyroid cancer; thyroiditis; hyperthyroidism; hypothyroidism; advanced imaging

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Management of Attention Deficit Hyperactivity Disorder (ADHD)

edited by

Alessandro Pallucchini

submission deadline 15 May 2026 | Viewed by 223 | Submission Open

Keywords: ADHD; addiction; neurodevelopmental disorders; levomethadone

(This special issue belongs to the Section Mental Health)

Mechanisms and Management of Intracerebral Hemorrhage

edited by Emanuela Crobeddu

submission deadline 15 May 2026 | Viewed by 188 | Submission Open

Keywords: intracerebral hemorrhage; arteriovenous malformation (AVM); dural arteriovenous fistula (DAVF); cavernoma; neuroinflammation; blood– brain barrier; hematoma evacuation; neuroprotection; imaging technologies; vascular lesions

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates on Pediatric Surgery

edited by Carlos Theodore Huerta and Eduardo Alfonso Perez

submission deadline 15 May 2026 | Viewed by 160 | Submission Open

Keywords: pediatric surgery; robotic-assisted surgery; artificial intelligence; enhanced recovery after surgery; minimally inva-sive surgery; augmented reality

(This special issue belongs to the Section Clinical Pediatrics)

Pediatric Pulmonology: Current Hurdles and Future Perspectives

edited by Isabel Delgado-Pecellín and Anselmo Andrés-Martín

submission deadline 15 May 2026 | Viewed by 128 | Submission Open

Keywords: interstitial lung diseases; neonatal screening; complex chronic patients; home mechanical ventilation; severe asthma; telemonitoring; lung development; cystic fibrosis; genetics

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Updates on Maternal Fetal Medicine: 2nd Edition

edited by

Roberta Granese

and

Gabriele Tonni

submission deadline 15 May 2026 | Viewed by 122 | Submission Open

Keywords: diabetes in pregnancy; hypertension in pregnancy; cholestasis in pregnancy; endocrine disorder in pregnancy; sepsis in pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Damage Control Surgery: New Insights into Resuscitation, Operative Strategies and Complications

edited by

Bruno de La Villéon

submission deadline 15 May 2026 | Viewed by 110 | Submission Open

Keywords: damage control surgery; damage control resuscitation; polytrauma management; massive transfusion protocol; hemorrhagic shock; trauma laparotomy; staged laparotomy; temporary abdominal closure; multidisciplinary trauma care

(This special issue belongs to the Section General Surgery)

Root Canal Treatment and Healing Outcomes: Clinical Application of Endodontic Biomaterials and Postoperative Management

edited by

Fausto Zamparini

Carlo Prati

and

Andrea Spinelli

submission deadline 15 May 2026 | Viewed by 82 | Submission Open

Keywords: root canal treatment; healing outcomes; endodontic biomaterials; bioceramic sealers; postoperative management; clinical evidence; periapical healing; post operative pain; dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Heart Failure: Challenges and Future Options

edited by Pedro Caravaca-Pérez and Marta Farrero-Torres

submission deadline 15 May 2026 | Viewed by 58 | Submission Open

Keywords: heart failure; cardiorenal syndrome; heart transplantation; ventricular assist devices; biomarkers; precision medicine; advanced therapies; diuretic resistance; risk stratification; multidisciplinary care

(This special issue belongs to the Section Cardiovascular Medicine)

Head and Neck Cancer: Clinical Diagnosis and Treatment

edited by Enrique Sanz-Garcia, Nicole Chau and Neus Baste

submission deadline 15 May 2026 | Viewed by 42 | Submission Open

Keywords: head and neck; multidisciplinary approaches; biomarkers; early detection; therapies

(This special issue belongs to the Section Otolaryngology)

Hypertrophic Cardiomyopathy: Lights and Shadows of Structural Pharmacological Treatment

edited by Daniel Dalos

submission deadline 15 May 2026 | Viewed by 39 | Submission Open

Keywords: hypertrophic cardiomyopathy; treatment; myosin inhibition; ventricular arrhythmia; atrial fibrillation

(This special issue belongs to the Section Cardiology)

Comprehensive Hernia Surgery: From Clinical Diagnosis to Postoperative Care

edited by Luca Regusci

submission deadline 15 May 2026 | Viewed by 26 | Submission Open

Keywords: ventral hernia; complexe hernias; botox treatment; laparoscopic surgery; robotic surgery

(This special issue belongs to the Section General Surgery)

Spinal Disorders: Current Treatment and Future Opportunities: Part III

edited by

Alan H Daniels

submission deadline 15 May 2026 | Viewed by 7 | Submission Open

Keywords: spine; spine surgery; spondylolisthesis; scoliosis; cervical myelopathy; spine surgery training; disc replacement; spine trauma; spine infection; spine fracture; spinal epidural abscess

(This special issue belongs to the Section Orthopedics)

Cardiovascular Disease in the Elderly: Prevention and Diagnosis

edited by Ioana Dana Alexa, Gabriel Ioan Prada and

Ciprian Rezus

submission deadline 20 May 2026 | 7 articles | Viewed by 19312 | Submission Open

Keywords: cardiovascular risk factors; elderly patients; frailty; sarcopenia; heart rate variability; insulin resistance; physical resilience; intrinsic capacity; diastolic dysfunction

(This special issue belongs to the Section Cardiovascular Medicine)

New Advances in Wound Healing and Skin Wound Treatment

edited by Hajime Matsumura

submission deadline 20 May 2026 | 8 articles | Viewed by 13428 | Submission Open

Keywords: trauma wound; burns; chronic wound; DFU; VLU; ischemic wound; regenerative medicine in wound care; debridement; biofilm; wound dressing; antimicrobial treatment

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Endometriosis: Clinical Challenges and Prognosis

edited by

Francisco Artacho-Cordon

submission deadline 20 May 2026 | 5 articles | Viewed by 8231 | Submission Open

Keywords: endometriosis; therapy; rehabilitation; psychology; diagnostics; ultrasound imaging; metabolomics; prognosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Chronic Lung Conditions: Integrative Approaches to Long-Term Care

edited by

Antigona Carmen Trofor

submission deadline 20 May 2026 | 4 articles | Viewed by 8056 | Submission Open

Keywords: chronic lung conditions: chronic non-infectious lung disease and post-respiratory infectious syndromes; including TB sequelae; TB MDR; post-COVID-19; and bronchiectasis; long-term care; integrative approach; multidisciplinary; multimorbidity; outcomes

(This special issue belongs to the Section Respiratory Medicine)

Novel Insights into the Prevention and Treatment of Contact Dermatitis

edited by

Cara Bieck

, Christoph Skudlik, Swen Malte John and

Albert Nienhaus

submission deadline 20 May 2026 | 3 articles | Viewed by 7107 | Submission Open

Keywords: allergic; allergy; contact dermatitis; irritant; occupation; prevention; sensitization; skin; therapy; treatment

(This special issue belongs to the Section Dermatology)

New Advances in Myasthenia Gravis

edited by Shingo Konno

submission deadline 20 May 2026 | 3 articles | Viewed by 4918 | Submission Open

Keywords: myasthenia gravis; clinical trials; translational research; drug repurposing; biological markers; experimental autoimmune myasthenia gravis

(This special issue belongs to the Section Clinical Neurology)

Advances in Retinal Diseases—Mechanisms, Diagnostics, and Emerging Therapies

edited by

Minzhong Yu

submission deadline 20 May 2026 | 2 articles | Viewed by 3512 | Submission Open

Keywords: inherited retinal diseases; age-related macular degeneration; diabetic retinopathy; multimodal retinal imaging; treatment

(This special issue belongs to the Section Ophthalmology)

New Advances in Uterus and Ovarian Transplantation: 2nd Edition

edited by

Elliott G. Richards

submission deadline 20 May 2026 | 2 articles | Viewed by 3470 | Submission Open

Keywords: uterus transplantation; gynaecological surgery; endometriosis; IVF; fibroids; reproductive medicine; laparoscopic surgery; assisted reproductive technology; reproductive endocrinology

(This special issue belongs to the Section Obstetrics & Gynecology)

Updates on Cardiac Pacing and Electrophysiology

edited by

Axel Brandes

submission deadline 20 May 2026 | 2 articles | Viewed by 3386 | Submission Open

Keywords: pacemaker; conduction system pacing; leadless pacemaker; implantable cardioverter– defibrillator; ICD; extravascular ICD; S-ICD; lead extraction; supraventricular tachycardia; ventricular tachycardia; cardio-neuro ablation

(This special issue belongs to the Section Cardiology)

Prostate Cancer: Diagnosis, Clinical Management and Prognosis

edited by Giovanni Muto

submission deadline 20 May 2026 | 3 articles | Viewed by 3258 | Submission Open

Keywords: prostate cancer; diagnosis; clinical management; prognosis; treatments

(This special issue belongs to the Section Nephrology & Urology)

Clinical Update in Pulmonary Rehabilitation

edited by Akira Tamaki

submission deadline 20 May 2026 | 3 articles | Viewed by 3009 | Submission Open

Keywords: pulmonary rehabilitation; chronic obstructive pulmonary disease; interstitial lung disease; sarcopenia; respiratory sarcopenia; respiratory muscle training; nutritional intervention

(This special issue belongs to the Section Respiratory Medicine)

Cirrhosis and Its Complications: Prognosis and Clinical Management

edited by

Ana-Maria Singeap

submission deadline 20 May 2026 | 2 articles | Viewed by 2060 | Submission Open

Keywords: cirrhosis; complications; spontaneous bacterial peritonitis; portal hypertension; ascites; hepatorenal syndrome; hepatic encephalopathy; liver transplantation; acute-on-chronic liver failure; hepatocellular carcinoma; quality of life; prognosis; clinical management

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Application of Knee Arthroscopy

edited by

Francesco Bosco

and Alessandro Carrozzo

submission deadline 20 May 2026 | 3 articles | Viewed by 1928 | Submission Open

Keywords: knee surgery; arthroscopy; orthopedics; sport medicine; clinical outcomes; ligament reconstruction; meniscal repair; cartilage; postoperative rehabilitation; knee joint; tissue repair; joint preservation

(This special issue belongs to the Section Orthopedics)

Research Progress in Pediatric Endocrinology

edited by

Federico Baronio

submission deadline 20 May 2026 | 1 articles | Viewed by 1158 | Submission Open

Keywords: pediatric endocrinology; rare endocrine disorders; precision medicine; congenital adrenal hyperplasia (CAH); short stature genetics; severe childhood obesity; glp-1 receptor agonists; endocrine disruptors; artificial intelligence (AI) in endocrinology; newborn screening

(This special issue belongs to the Section Clinical Pediatrics)

Advances in Fertility Preservation

edited by Dunja Maria Baston-Büst

submission deadline 20 May 2026 | 1 articles | Viewed by 1068 | Submission Open

Keywords: fertility preservation; gonadotoxic treatment; chemotherapy; transgender; cryopreservation; ejaculate; testicular tissue; mature oocytes; immature oocytes; ovarian tissue; ovarian cortex

(This special issue belongs to the Section Obstetrics & Gynecology)

Acute Ischemic Stroke: Current Status and Future Challenges—2nd Edition

edited by

Lucio D'Anna

submission deadline 20 May 2026 | 2 articles | Viewed by 921 | Submission Open

Keywords: acute ischemic stroke; atrial fibrillation; endovascular thrombectomy; intravenous thrombolysis; direct oral anticoagulants

(This special issue belongs to the Section Clinical Neurology)

Advances in Minimally Invasive Otolaryngology: Precision Techniques and Functional Outcomes

edited by Giovanni Colombo and

Matteo Di Bari

submission deadline 20 May 2026 | 2 articles | Viewed by 677 | Submission Open

Keywords: advances in otolaryngology; endoscopic surgery; head and neck surgery; functional outcomes; quality of life

(This special issue belongs to the Section Otolaryngology)

Cardiac Imaging in Cardiovascular Disorders

edited by Leif-Christopher Engel

submission deadline 20 May 2026 | Viewed by 546 | Submission Open

Keywords: coronary CT angiography; cardiac magnetic resonance imaging; molecular imaging; echocardiography; stress echocardiography; myocardial perfusion imaging

(This special issue belongs to the Section Cardiology)

Surgical Management of Complex Spinal Pathologies: Challenges and Innovations

edited by

Spyridon Komaitis

submission deadline 20 May 2026 | 1 articles | Viewed by 507 | Submission Open

Keywords: complex spinal surgery; adult spinal deformity; complex degenerative pathologies; revision spine surgery; spinal oncology; robotics; navigation; surgical outcomes

(This special issue belongs to the Section Orthopedics)

Clinical Management and Long-Term Prognosis in Intensive Care

edited by

Wioletta Mędrzycka-Dąbrowska

and

Sandra Lange

submission deadline 20 May 2026 | 2 articles | Viewed by 473 | Submission Open

Keywords: intensive care; post-intensive care syndrome; patient safety; improved survival; mental health; mechanical ventilation

(This special issue belongs to the Section Intensive Care)

Percutaneous Coronary Intervention: Latest Advances and Future Prospects

edited by

Alessandro Mandurino-Mirizzi

submission deadline 20 May 2026 | 1 articles | Viewed by 457 | Submission Open

Keywords: percutaneous coronary intervention; coronary artery disease; intravascular imaging; intracoronary physiology; high-risk percutaneous coronary intervention; calcified coronary stenosis; chronic total occlusion; bifurcation disease

(This special issue belongs to the Section Cardiology)

Advances in Clinical Rheumatology—2nd Edition

edited by

Jacopo Ciaffi

submission deadline 20 May 2026 | 1 articles | Viewed by 450 | Submission Open

Keywords: rheumatoid arthritis; spondylarthritis; interventional; osteoporosis; complex regional pain syndrome

(This special issue belongs to the Section Immunology & Rheumatology)

Cutting Edge Research on Total Knee Arthroplasty

edited by

Nahum Rosenberg

submission deadline 20 May 2026 | 1 articles | Viewed by 435 | Submission Open

Keywords: total knee arthroplasty; robotic-assisted surgery; computer-navigated arthroplasty; implant design; kinematic alignment; enhanced recovery pathways; patient-reported outcomes; artificial intelligence in orthopedics; revision surgery

(This special issue belongs to the Section Orthopedics)

Physiotherapy in Clinical Practice: From Assessment to Rehabilitation

edited by

Inés Llamas Ramos

and

Rocío Llamas-Ramos

submission deadline 20 May 2026 | 1 articles | Viewed by 402 | Submission Open

Keywords: clinical assessment; rehabilitation; clinical practice; patient-centered care; physiotherapy innovation

(This special issue belongs to the Section Clinical Rehabilitation)

Total Joint Arthroplasty: Innovations, Outcomes, and Challenges—Second Edition

edited by Hendrik Kohlhof

submission deadline 20 May 2026 | 1 articles | Viewed by 329 | Submission Open

Keywords: knee and hip replacements; joint replacement; biomechanics; revision arthroplasty; orthogeriatrics and perioperative management

(This special issue belongs to the Section Orthopedics)

New Therapies for Diabetic Foot Ulcer Management

edited by

Irene Sanz-Corbalan

and

Raúl J. Molines Barroso

submission deadline 20 May 2026 | Viewed by 300 | Submission Open

Keywords: diabetic foot disease; diabetic foot ulcers; wound healing; biomarkers; telemedicine; artificial intelligence; preven-tive strategies; advanced therapies; amputation prevention; diabetes complications; novel treatments

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Updates of Physical Therapy in Rehabilitation

edited by

Sofia Xergia

submission deadline 20 May 2026 | Viewed by 260 | Submission Open

Keywords: neurological rehabilitation; musculoskeletal rehabilitation; special populations; new technology in physical therapy

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Updates in Transfusion Medicine and Patient Blood Management

edited by

Carlos Jerico

and

José Antonio García-Erce

submission deadline 20 May 2026 | Viewed by 231 | Submission Open

Keywords: anaemia; bleeding; blood transfusion; patient blood management; transfusion medicine

(This special issue belongs to the Section Hematology)

New Horizons in Aortic Valve Replacement

edited by Abdellaziz Dahou

submission deadline 20 May 2026 | Viewed by 192 | Submission Open

Keywords: aortic valve; aortic stenosis; TAVR; SAVR; valve durability; aortic valve replacement; transcatheter aortic valve replacement; surgical aortic valve replacement

(This special issue belongs to the Section Cardiology)

Novel Approaches in Cataract and Refractive Surgery

edited by Stephen T. Armenti

submission deadline 20 May 2026 | Viewed by 161 | Submission Open

Keywords: cataract surgery; complex cataract surgery; secondary intraocular lens surgery; refractive surgery (LASIK; PRK; SMILE); astigmatism correction; multifocal intraocular lenses; femtosecond laser; dropless cataract surgery

(This special issue belongs to the Section Ophthalmology)

Surgery in the Era of Neoadjuvant Immune Checkpoint Inhibitors Therapy for Thoracic Oncology

edited by

Mohsen Ibrahim

submission deadline 20 May 2026 | Viewed by 120 | Submission Open

Keywords: neoadjuvant therapy; immune checkpoint inhibitors; unresectable disease; lung cancer; locally advanced lung cancer

(This special issue belongs to the Section General Surgery)

Artificial Intelligence in Exercise, Rehabilitation and Health Promotion: A Clinical Perspective

edited by

Ki-Hyuk Lee

and

Koji Koyama

submission deadline 20 May 2026 | Viewed by 117 | Submission Open

Keywords: artificial intelligence; machine learning and deep learning; large language models (LLMs); explainable AI; exercise and physical activity; rehabilitation and sports medicine; clinical applications; chronic disease and preventive health; digital health and big data analytics

(This special issue belongs to the Section Sports Medicine)

Clinical Diagnosis and Management of Obstructive Sleep Apnea Syndrome

edited by

Graziano Montaruli

Domenico Ciavarella

and

Michele Tepedino

submission deadline 20 May 2026 | 1 articles | Viewed by 109 | Submission Open

Keywords: obstructive sleep apnea (OSA); apnea-hypopnea index (AHI); oxygen desaturation index (ODI); mandibular advancement device (MAD); polysomnography; upper airway; continuous positive airway pressure (C-PAP)

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Spine Surgery: Current Challenges and Opportunities

edited by Kambiz Sarahrudi

submission deadline 20 May 2026 | Viewed by 100 | Submission Open

Keywords: vertebral fracture; spine trauma; spinal cord injury; adjacent segment degeneration; infection; spondylodiscitis; verte-bral metastasis; osteoporotic fracture; fracture of sacrum; disk degeneration; degenerative spine surgery; minimally invasive spine surgery

(This special issue belongs to the Section Orthopedics)

Current Challenges in Oral and Maxillofacial Surgery

edited by

Federica Canfora

and Lucia Memé

submission deadline 20 May 2026 | Viewed by 83 | Submission Open

Keywords: oral and maxillofacial surgery; surgical management; virtual surgical planning; postoperative management; orthog-nathic surgery; reconstructive techniques; minimally invasive surgery; digital technologies; 3D printing

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Challenges in Pancreatitis Management

edited by

Yusuke Tando

submission deadline 20 May 2026 | Viewed by 81 | Submission Open

Keywords: acute pancreatitis; chronic pancreatitis; medical management; surgical management; nutritional support; pancreatic diabetes; clinical research; reviews

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Progress in Oral and Maxillofacial Surgery

edited by Luis M. Junquera and Giuseppe Consorti

submission deadline 20 May 2026 | Viewed by 77 | Submission Open

Keywords: oral and maxillofacial surgery; craniofacial surgery; facial deformity; cleft lip and palate; TMJ surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Displaying special issue 1251-1300 on page 26 of 32.

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