Endometriosis: Clinical Challenges and Prognosis

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".

Deadline for manuscript submissions: 25 May 2025 | Viewed by 1704

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Guest Editor
Department of Radiology and Physical Medicine, University of Granada, E-18016 Granada, Spain
Interests: women health; chronic pain; physical fitness; functional impairments; endometriosis
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Special Issue Information

Dear Colleagues,

Endometriosis is among the most prevalent gynecologic diseases with estimated prevalence rates nearly 10% of women on reproductive age worldwide. Characterized by the presence of endome-trial-like tissue outside the uterine cavity, this complex condition causes a vast range of symptoms in suffering women, including both physical and mental problems, which in turn, ameliorates their quality of life. Conventional treatments for endometriosis usually include medical and surgical treatments, although elevated rates of treatment failure has been observed. Therefore, there is a need to optimize current treatment regimens as well as to explore new therapeutics that could improve quality of life of those women unresponsive to conventional treatments. Moreover, there is a need to develop non-invasive or minimally invasive diagnostic tools to reduce the large diagnostic delay observed in this disease.  

In this Special Issue, we invite researchers to contribute with manuscripts encompassing both clinical and preclinical studies, including but not limited to original articles, systematic reviews, meta-analyses, and study protocols. Submissions that utilize qualitative or mixed methods approaches to address unmet needs, identify barriers, or highlight research priorities are particularly encouraged.

Dr. Francisco Artacho-Cordon
Guest Editor

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Keywords

  • endometriosis
  • therapy
  • rehabilitation
  • psychology
  • diagnostics
  • ultrasound imaging
  • metabolomics
  • prognosis

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Published Papers (1 paper)

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8 pages, 21772 KiB  
Case Report
Deep Infiltrating Endometriosis of the Left Ureter Managed with Laparoscopic Ureterolysis Combined with Allium Ureteral Self-Expandable Stent: A Case Report
by Marcin Jozwik, Magdalena Miłobędzka, Joanna Wojtkiewicz, Jörg Neymeyer, Artur Jakimiuk and Maciej Jozwik
J. Clin. Med. 2024, 13(22), 6769; https://doi.org/10.3390/jcm13226769 - 11 Nov 2024
Viewed by 1367
Abstract
Introduction: In endometriosis, urinary tract involvement occurs in 1–5.5% of cases, where the ureter is affected in 9–23%. Unfortunately, endometriosis may remain asymptomatic even with significant anatomical progression. A delay in the diagnosis and treatment of ureteral endometriosis may result in hydronephrotic [...] Read more.
Introduction: In endometriosis, urinary tract involvement occurs in 1–5.5% of cases, where the ureter is affected in 9–23%. Unfortunately, endometriosis may remain asymptomatic even with significant anatomical progression. A delay in the diagnosis and treatment of ureteral endometriosis may result in hydronephrotic kidney damage and functional impairment. Methods: We present a case of a 36-year-old woman with a left ureteral stricture caused by deep infiltrating endometriosis accompanied by severe kidney-induced arterial hypertension. In March 2022, the patient underwent both laparoscopic excision/evaporation of deep infiltrating endometriosis from the left ovarian fossa and left ureterolysis, followed by an ureterorenoscopic dilatation of the left ureter via the placement of an Allium self-expandable stent. Results: This stent was successfully removed 18 months later. A computed tomography check-up confirmed normal ureteral patency with no signs of endometriosis. Elevated blood pressure also resolved. Conclusions: Deep infiltrating endometriosis can lead to asymptomatic yet serious complications. A successful treatment of ureteral endometriosis may require multidisciplinary management, including a simultaneous laparoscopic and ureterorenoscopic approach. Ureteral stent placement is a minimally invasive state-of-the-art solution for ureteral stricture(s) and should be considered the first choice in women of reproductive age suffering from ureteral deep infiltrating endometriosis. Full article
(This article belongs to the Special Issue Endometriosis: Clinical Challenges and Prognosis)
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