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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Aiming for Early Detection and Prevention of Pulmonary Diseases submission deadline 20 Nov 2026 | 1 articles | Viewed by 1045 | Submission Open
Keywords: early diagnosis; prevention strategies; respiratory diseases; artificial intelligence; asthma; chronic obstructive pulmonary disease (COPD); interstitial lung disease; sleep-disordered breathing
(This special issue belongs to the Section Respiratory Medicine)
Clinical Diagnosis and Management of Neonatal Diseases—Second Edition
edited by and Ayala Gover
submission deadline 20 Nov 2026 | 2 articles | Viewed by 1039 | Submission Open
Keywords: newborn; preterm; neonatal intensive care; low birth weight; point-of-care ultrasound; neonatal monitoring
(This special issue belongs to the Section Clinical Pediatrics)
Clinical Advances in Drug Safety and Polypharmacy submission deadline 20 Nov 2026 | 2 articles | Viewed by 976 | Submission Open
Keywords: polypharmacy; medication safety; adverse drug reactions; drug–drug interactions; pharmacovigilance; artificial intelligence in healthcare; precision medicine; deprescribing; pharmacoepidemiology
(This special issue belongs to the Section Pharmacology)
Advances in Thoracic Surgery: Minimally Invasive Techniques, Precision Lung Resection, and Emerging Technologies
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 965 | Submission Open
Keywords: minimally invasive thoracic surgery; robotic-assisted thoracic surgery (RATS); video-assisted thoracic surgery (VATS); precision lung resection; lung cancer surgery; segmentectomy; 3D imaging and surgical planning; extra-corporeal lung support
(This special issue belongs to the Section General Surgery)
Towards an Improved Understanding of Alzheimer's and Related Dementias: Interdisciplinary and Clinical Progress submission deadline 20 Nov 2026 | 2 articles | Viewed by 954 | Submission Open
Keywords: Alzheimer’s disease; related dementias; neurodegeneration; biomarkers; neuroimaging; early diagnosis; cognitive decline; clinical management; therapeutic interventions; psychosocial care; risk factors; dementia prevention
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in HPV-Related Disease submission deadline 20 Nov 2026 | 1 articles | Viewed by 949 | Submission Open
Keywords: gynecological cancers; HPV; HPV vaccine; cervical cancer; precancerous lesions diagnostics
(This special issue belongs to the Section Obstetrics & Gynecology)
Advancing Mechanical Ventilation in Critical Care: From Clinical Foundations to Personalized Strategies
edited by
submission deadline 20 Nov 2026 | 2 articles | Viewed by 946 | Submission Open
Keywords: mechanical ventilation; acute respiratory distress syndrome (ARDS); lung-protective ventilation; patient–ventilator interaction; personalized (precision) critical care
(This special issue belongs to the Section Intensive Care)
Challenges in the Diagnosis and Management of Chronic Respiratory Diseases submission deadline 20 Nov 2026 | 2 articles | Viewed by 819 | Submission Open
Keywords: chronic respiratory diseases; long-term respiratory care; comorbidities; COPD; asthma; interstitial lung disease; pulmonary rehabilitation
(This special issue belongs to the Section Respiratory Medicine)
Heart Valve Surgery: Challenges and Advances in Conventional Surgery and Transcatheter Valve Therapy
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 815 | Submission Open
Keywords: mitral valve surgery; aortic valve surgery; tricuspid valve surgery; ross procedure; david procedure; transcatheter valve therapy; homograft valve replacement; infective endocarditis surgery
(This special issue belongs to the Section Cardiology)
Clinical Updates on Oral Health and Dental Care
edited by Wojciech Niemczyk and Rafał Wiench
submission deadline 20 Nov 2026 | 1 articles | Viewed by 808 | Submission Open
Keywords: oral health management; dental care; oral inflammatory diseases; oral diseases; preventive dentistry; periodontitis; oral medicine; clinical dentistry; dental surgery; periodontology
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Latest Advances and Prospects in Urogynecology and Pelvic Floor Surgery
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 808 | Submission Open
Keywords: urogynecology; pelvic floor disorders; pelvic organ prolapse; urinary incontinence; fecal incontinence; minimally invasive surgery; pelvic floor imaging; vaginal surgery; pelvic pain syndrome
(This special issue belongs to the Section Obstetrics & Gynecology)
New Concepts in Diagnostic and Surgical HPB Technology
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 784 | Submission Open
Keywords: HPB surgery; minimal invasive approach; imaging; artificial intelligence; robotic surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Hypertrophic Cardiomyopathy: From the Researcher Bench to the Clinical Patient Bedside
edited by , and Dejana R. Popović
submission deadline 20 Nov 2026 | 1 articles | Viewed by 725 | Submission Open
Keywords: hypertrophic cardiomyopathy; advanced imaging techniques; echocardiographic; cardiac magnetic resonance; biomarkers; surgical and interventional procedures
(This special issue belongs to the Section Cardiology)
Obesity and the Airway: Disease Mechanisms, Associated Conditions, and Management
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 721 | Submission Open
Keywords: obesity; airway; inflammation; rhinosinusitis; cerebrospinal fluid leak; asthma; chronic obstructive pulmonary disease; sleep; obstructive sleep apnea; intubation; laryngopharyngeal reflux; laryngotracheal stenosis
(This special issue belongs to the Section Respiratory Medicine)
Current Advances in Spinal Cord Stimulation Therapy
edited by Alessandro Dario
submission deadline 20 Nov 2026 | 1 articles | Viewed by 696 | Submission Open
Keywords: spinal cord stimulation; epidural stimulation; transcutaneous spinal cord stimulation; spasticity; neuropathic pain; Parkinson’s disease; paraplegia; Persistent Spinal Pain Syndrome Type 1; Persistent Spinal Pain Syndrome Type 2; diabetic polyneuropathy; electrical waveforms
(This special issue belongs to the Section Clinical Neurology)
Prostate Cancer: Clinical Advances and Prognosis Now and in the Near Future
edited by Josip Španjol
submission deadline 20 Nov 2026 | 1 articles | Viewed by 691 | Submission Open
Keywords: prostate cancer; immunotherapy; clinical trials; personalized medicine; artificial intelligence; robotic surgery; radical prostatectomy; radiotherapy
(This special issue belongs to the Section Nephrology & Urology)
Psychological Safety: Bodily and Psychological Determinants in Clinical Settings
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 677 | Submission Open
Keywords: psychological safety; fear; psychological trauma; shame; dissociation; neuroception; trust; polyvagal theory
(This special issue belongs to the Section Mental Health)
Endocarditis: Clinical Updates on Diagnosis, Treatment and Management
edited by Katarzyna Holcman
submission deadline 20 Nov 2026 | 1 articles | Viewed by 666 | Submission Open
Keywords: infective endocarditis; PET; SPECT; echocardiography; antimicrobial therapy; cardiac surgery; multimodality imaging
(This special issue belongs to the Section Cardiology)
Management Strategies for Traumatic Brain Injury in Neurocritical Care Unit
edited by Etrusca Brogi
submission deadline 20 Nov 2026 | 1 articles | Viewed by 649 | Submission Open
Keywords: traumatic brain injury; neurocritical care; intracranial pressure; cerebral perfusion; neuroprotection; TBI management; critical care strategies; outcome prediction; rehabilitation; monitoring
(This special issue belongs to the Section Clinical Neurology)
New Technological Treatments and Methods in Neurorehabilitation
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 590 | Submission Open
Keywords: neurorehabilitation; robotics; virtual reality; exoskeleton; humankinesiology physiotherapy; stroke; parkinson's disease; gait; physical rehabilitation; rehabilitation interventions
(This special issue belongs to the Section Clinical Neurology)
Interventional Pulmonology: Advances and Future Directions—2nd Edition
edited by Martina Ferioli and Piero Candoli
submission deadline 20 Nov 2026 | 1 articles | Viewed by 543 | Submission Open
Keywords: interventional pulmonology; lung nodule; lung cancer; diagnosis; bronchoscopy; rigid bronchoscopy; airway stent; airway stenosis; mediastinal staging
(This special issue belongs to the Section Respiratory Medicine)
Hip Fracture and Surgery: Clinical Updates and Challenges: 2nd Edition
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 541 | Submission Open
Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty
(This special issue belongs to the Section Orthopedics)
New Updates in Kidney Cancer submission deadline 20 Nov 2026 | Viewed by 531 | Submission Open
Keywords: renal cell carcinoma (RCC); robot-assisted partial nephrectomy (RAPN); artificial intelligence in oncology; cryoablation; kidney cancer management
(This special issue belongs to the Section Nephrology & Urology)
Innovative Neurosurgery: Scientific Breakthroughs and Modern Practice
edited by Wolfgang Senker and Matthias Gmeiner
submission deadline 20 Nov 2026 | 1 articles | Viewed by 482 | Submission Open
Keywords: neurosurgery; innovative neurosurgery; clinical translational neuroscience; precision surgery; advanced neuroimaging; minimally invasive neurosurgery; robotic and endoscopic techniques; artificial intelligence in neurosurgery; spine and craniovertebral surgery; functional and vascular neurosurgery; surgical innovation and outcomes
(This special issue belongs to the Section Clinical Neurology)
Cardiomyopathy: Advances in Clinical Diagnosis and Treatment
edited by and Ali Amr
submission deadline 20 Nov 2026 | 1 articles | Viewed by 448 | Submission Open
Keywords: cardiomyopathy; precision medicine; heart failure; cardiac imaging; genetics; myocardial biopsy; arrhythmias; targeted therapy
(This special issue belongs to the Section Cardiology)
Diagnosis, Monitoring, and Treatment of Myocardial Infarction: 2nd Edition
edited by
submission deadline 20 Nov 2026 | Viewed by 424 | Submission Open
Keywords: myocardial infarction; diagnosis; monitoring; treatment; acute MI
(This special issue belongs to the Section Cardiovascular Medicine)
Quality of Life in Patients with Gynecological Cancers
edited by , and Monika Englert-Golon
submission deadline 20 Nov 2026 | Viewed by 410 | Submission Open
Keywords: quality of life; gynecology oncology; ovarian cancer; breast cancer; cervical cancer; endometrial cancer; women; gynecological diseases; oncological diseases
(This special issue belongs to the Section Obstetrics & Gynecology)
The Use of Circulating Extracellular Vesicles as a Tool in the Diagnosis, Monitoring and Treatment of Disease submission deadline 20 Nov 2026 | Viewed by 390 | Submission Open
Keywords: circulating extracellular vesicles; regenerative medicine; biomarker; diagnosis; exosomes; liquid biopsy
(This special issue belongs to the Section Clinical Laboratory Medicine)
Cardiomyopathies: A Contemporary Review of Advances and Clinical Strategies
edited by Carla Contaldi
submission deadline 20 Nov 2026 | Viewed by 360 | Submission Open
Keywords: cardiomyopathies; heart failure; genetic mutations; molecular mechanisms; advanced cardiac imaging; cardiac MRI; precision medicine; risk stratification
(This special issue belongs to the Section Cardiology)
Myocardial Infarction: The Latest Advances and Prospects
edited by and Antonios Ziakas
submission deadline 20 Nov 2026 | Viewed by 343 | Submission Open
Keywords: coronary artery disease; myocardial infarction; PPCI; echocardiography; antiplatelet agents; radial access; global longitudinal strain
(This special issue belongs to the Section Cardiology)
Recent Advances in Hip and Knee Arthroplasty: Clinical Trends
edited by
submission deadline 20 Nov 2026 | Viewed by 323 | Submission Open
Keywords: hip arthroplasty; knee arthroplasty; total joint replacement; osteoarthritis; surgical techniques; implant innovation; revision strategies; complication prevention; revision strategies
(This special issue belongs to the Section Orthopedics)
Integrated Management of Cardiorenal Metabolic Syndrome: From Obesity to Chronic Kidney Disease submission deadline 20 Nov 2026 | Viewed by 293 | Submission Open
Keywords: cardiorenal metabolic syndrome; adipose tissue dysfunction; Insulin resistance; ectopic adiposity; cardiometabolic therapies
(This special issue belongs to the Section Endocrinology & Metabolism)
Advanced Technologies in Thoracic Anesthesia
edited by and
submission deadline 20 Nov 2026 | Viewed by 289 | Submission Open
Keywords: thoracic anesthesia; thoracic analgesia; preoperative management; enhanced recovery after surgery; thoracic Block; video-assisted thoracic surgery; robotic-assisted thoracic surgery; post-thoracotomy syndrome; airway device
(This special issue belongs to the Section Anesthesiology)
Recent Advances in the Diagnosis and Treatment of Breast Cancer submission deadline 20 Nov 2026 | Viewed by 285 | Submission Open
Keywords: breast cancer screening; diagnosis; surgery; radiotherapy; targeted treatment; neoadjuvant; quality of life
(This special issue belongs to the Section Oncology)
Advances in the Management of Cancer Pain
edited by Wojciech Leppert
submission deadline 20 Nov 2026 | Viewed by 268 | Submission Open
Keywords: analgesia; analgesics; cancer patients; chronic pain; pain in cancer patients; pain assessment; non-opioids; opioid analgesics; adjuvant analgesics; non-pharmacology methods of pain management
(This special issue belongs to the Section Epidemiology & Public Health)
Advances and Challenges in the Diagnosis and Treatment of Epilepsy
edited by
submission deadline 20 Nov 2026 | Viewed by 266 | Submission Open
Keywords: epilepsy; diagnosis; treatment; epilepsy surgery; clinical management
(This special issue belongs to the Section Clinical Neurology)
Colorectal Surgery: New Insights and Emerging Trends
edited by Marisa D. Santos, Nuno José Gomes Rama and Manuel Limbert
submission deadline 20 Nov 2026 | Viewed by 265 | Submission Open
Keywords: colorectal surgery; minimally invasive colorectal surgery; colorectal laparoscopic surgery; robotic-assisted colorectal surgery; precision colorectal surgery; enhanced recovery after surgery (ERAS); colorectal cancer; sphincter-preserving procedures; transanal surgery; pelvic floor surgery; personalized medicine; molecular profiling; biomarkers; artificial intelligence; image-guided surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Psychotic Disorders: Precision Diagnosis and Personalized Treatment
edited by
submission deadline 20 Nov 2026 | Viewed by 259 | Submission Open
Keywords: psychotic disorders; early detection; precision diagnosis; personalized interventions; functional recovery; personal recovery; cognitive remediation; psychosocial treatment; recovery-oriented care; individualized care plans; digital mental health; telepsychiatry; artificial intelligence; virtual reality; predictive modeling
(This special issue belongs to the Section Mental Health)
Hepato-Pancreato-Biliary (HPB) Surgery: Precision and Outcomes
edited by Florian W. R. Vondran, Felix Oldhafer and Celia Villodre
submission deadline 20 Nov 2026 | Viewed by 258 | Submission Open
Keywords: hepato-pancreato-biliary surgery; liver surgery; minimally invasive surgery; robotic surgery; multidisciplinary treatment
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Fertility and Reproductive Health in Women
edited by
submission deadline 20 Nov 2026 | Viewed by 257 | Submission Open
Keywords: female fertility; reproductive health; infertility; assisted reproductive technology; reproductive endocrinology; ovarian reserve; reproductive aging; PCOS; endometriosis; fertility preservation
(This special issue belongs to the Section Obstetrics & Gynecology)
Resuscitation and Shock: Evolving Concepts and Clinical Strategies in Acute Care
edited by , Barbara P. Fyntanidou and
submission deadline 20 Nov 2026 | Viewed by 244 | Submission Open
Keywords: resuscitation; shock; emergency medicine; critical care; hemodynamic monitoring; sepsis; trauma; vasopressors; fluid therapy; car-diopulmonary resuscitation (CPR); preclinical studies; cardiac arrest
(This special issue belongs to the Section Emergency Medicine)
Robotic Surgery in Urology: Current Updates and Innovations
edited by Scott Leslie
submission deadline 20 Nov 2026 | Viewed by 236 | Submission Open
Keywords: robotics; oncology; prostatectomy; nephrectomy; bladder; transplant; minimally-invasive; nephroureterectomy; reconstructive; pyeloplasty; novel; laparoscopic
(This special issue belongs to the Section Nephrology & Urology)
Advances in Adult Congenital Heart Disease: From Diagnosis to Long-Term Management
edited by Michael Huntgeburth
submission deadline 20 Nov 2026 | Viewed by 235 | Submission Open
Keywords: adult congenital heart disease; ACHD; long-term management; lifetime management; complications; arrhythmia; heart failure; endocarditis; pulmonary arterial hypertension; comorbidities; interventional treatment; surgical treatment; rehabilitation
(This special issue belongs to the Section Cardiology)
Innovations in Minimally Invasive and Personalized Urogynecology
edited by Günter Karl Noé and
submission deadline 20 Nov 2026 | Viewed by 228 | Submission Open
Keywords: urogynecology; pelvic floor disorders; minimally invasive reconstructive techniques; personalized and regenerative treatment strategies
(This special issue belongs to the Section Obstetrics & Gynecology)
Artificial Intelligence Applications in Urology
edited by , Rocco Papalia and Nicolas Carl
submission deadline 20 Nov 2026 | Viewed by 226 | Submission Open
Keywords: artificial intelligence; urology; machine learning; robotic surgery; digital pathology; predictive modeling
(This special issue belongs to the Section Nephrology & Urology)
New Challenges in Maternal–Fetal Medicine: 2nd Edition
edited by
submission deadline 20 Nov 2026 | Viewed by 224 | Submission Open
Keywords: thrombocytopenia in pregnancy; multiple pregnancies; placental abruption; DIC; sepsis; chorioamnionitis; cholestasis; postpartum hemorrhage; emergency cervical cerclage; problems in pregnancy and labor; pregnancy complications; spina bifida; fetal well-being evaluation
(This special issue belongs to the Section Obstetrics & Gynecology)
Application of Magnetic Resonance Imaging in Cardiovascular Disease
edited by Dhrubajyoti Bandyopadhyay, Aneesh S. Dhorepatil and
submission deadline 20 Nov 2026 | Viewed by 223 | Submission Open
Keywords: cardiac MRI; tricuspid regurgitation; parametric imaging; 4D flow; WIP; flow reserve; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advancements in Radiology of Joint and Musculoskeletal Diseases
edited by
submission deadline 20 Nov 2026 | Viewed by 221 | Submission Open
Keywords: sports injuries; ligament injuries; ankle injury; prognostic imaging; individualized imaging; imaging algorithms; lower-extremity injury; clinical insights; knee injuries; groin and hip pain
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Current Concepts of Cardio–Renal Interactions
edited by
submission deadline 20 Nov 2026 | Viewed by 218 | Submission Open
Keywords: AKI; cardiorenal syndrome; contrast; biomarkers; renal insufficiency; cardio-nephrology; organ crosstalk
(This special issue belongs to the Section Cardiovascular Medicine)
Echocardiography: Clinical Updates and Perspectives
edited by Isabella Leo and Giulia La Vecchia
submission deadline 20 Nov 2026 | Viewed by 217 | Submission Open
Keywords: echocardiography; cardiovascular imaging; three-dimensional echocardiography; speckle-tracking echocardiog-raphy; myocardial strain imaging; contrast echocardiography; transesophageal echocardiography; valvular heart disease; structural heart disease; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
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