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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Clinical Advances in Reconstructive Urology and Prosthetic Surgery
edited by Elisa Berdondini and
submission deadline 25 Jan 2027 | 1 articles | Viewed by 2969 | Submission Open
Keywords: reconstructive urology; penile prosthesis; artificial urinary sphincter; urethral stricture; reconstructive surgery; minimally invasive procedures
(This special issue belongs to the Section Nephrology & Urology)
High-Risk Pregnancy Management: From Prenatal Care to Postpartum Outcomes
edited by
submission deadline 25 Jan 2027 | 2 articles | Viewed by 2289 | Submission Open
Keywords: high-risk pregnancy; prenatal care; postpartum outcomes; postpartum mental health; birth trauma; AI in obstetrics; medico-legal liability; equity & culturally safe care; indigenous and rural/remote care; EMR-enabled decision support; quality trend monitoring; maternal morbidity and mortality; perinatal morbidity; standardized care bundles & pathways
(This special issue belongs to the Section Obstetrics & Gynecology)
Advancing Trends and Strategies in Vascular and Endovascular Surgery
edited by Karin Pfister and Fiona Rohlffs
submission deadline 25 Jan 2027 | 2 articles | Viewed by 1346 | Submission Open
Keywords: vascular surgery; endovascular surgery; carotid endarterectomy; peripheral vascular diseases; vascular imaging; aortic diseases; aortic aneurysm; arteriovenous malformation; pelvic venous disorder; endovenous procedures; pal-liative therapy concept
(This special issue belongs to the Section Vascular Medicine)
Interaction Between Systemic Diseases and Oral Diseases: 2nd Edition
edited by
submission deadline 25 Jan 2027 | 2 articles | Viewed by 1253 | Submission Open
Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjögren’s disease; liver transplantation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Management and Update of Aortic Dissection and Aortic Aneurysm Diseases
edited by
submission deadline 25 Jan 2027 | 1 articles | Viewed by 1150 | Submission Open
Keywords: aortic aneurysm; aortic dissection; aortic surgery; endovascular procedures
(This special issue belongs to the Section Cardiovascular Medicine)
Further Advances in Electrocardiography, Cardiac Arrhythmias, and Arrhythmogenic Disorders: 2nd Edition
edited by
submission deadline 25 Jan 2027 | 1 articles | Viewed by 1130 | Submission Open
Keywords: electrocardiography; cardiac arrhythmias; genetics; cardiac pacing; implantable cardioverter defibrillators; cardiac resynchronization therapy; magnetic resonance imaging; catheter ablation; arrhythmogenic disorders; channelopathy; cardiomyopathy
(This special issue belongs to the Section Cardiology)
Musculoskeletal Imaging and Intervention: 2nd Edition submission deadline 25 Jan 2027 | 2 articles | Viewed by 1039 | Submission Open
Keywords: ultrasound; invasive physiotherapy; minimally invasive surgical procedures; magnetic resonance; image analysis
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Advanced Image-Enhanced Endoscopy and Colonoscopy
edited by , and Simona Di Caro
submission deadline 25 Jan 2027 | 1 articles | Viewed by 1031 | Submission Open
Keywords: gastrointestinal endoscopy; colorectal cancer; endoscopic screening; artificial intelligence; chromoendoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cutting-Edge Strategies in Periodontal Disease: Proactive Prevention, Early Diagnosis, and Optimal Management
edited by
submission deadline 25 Jan 2027 | Viewed by 190 | Submission Open
Keywords: periodontitis; herbal medicine; dental plaque; pathogenesis related proteins; root planing; instrumentation; ultrasonic therapy
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Implant-Supported Prosthetic Rehabilitation: Current Concepts, Emerging Technologies and Long-Term Outcomes
edited by , Marius Manole and Cosmin Sinescu
submission deadline 25 Jan 2027 | Viewed by 115 | Submission Open
Keywords: prosthetic rehabilitation; dental implants; dental restorations; zirconia; digital dentistry; long-term outcomes; clini-cal biomaterials; immediate loading; clinical biomedical engineering; full-arch restoration; peri-implant health
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Technological Advances in Lumbar and Thoracic Spine Surgery: Current Evidence and Future Perspectives
edited by
submission deadline 25 Jan 2027 | Viewed by 96 | Submission Open
Keywords: lumbar spine surgery; thoracic spine surgery; minimally invasive spine surgery; endoscopic spinal surgery; robotic-assisted surgery; artificial intelligence; machining learning; lumbar interbody fusion; spinal biologics; adjacent segment disease; patient-reported outcomes; revision spinal surgery; ossification of posterior longitudinal ligament
(This special issue belongs to the Section Orthopedics)
Mind–Body Connection: The Impact of Mental Health on Physical Well-Being
edited by
submission deadline 30 Jan 2027 | 5 articles | Viewed by 12034 | Submission Open
Keywords: mind–body connection; mental health; well-being; metabolic balance; immune system; chronic medical conditions; body perception; self-image; eating disorders; psychosomatic disorders; psychosomatic medicine; innovative thera-peutic approaches; mindfulness; mind-wandering; integrated healthcare
(This special issue belongs to the Section Mental Health)
Applications of Artificial Intelligence (AI) in Surgery submission deadline 30 Jan 2027 | 1 articles | Viewed by 620 | Submission Open
Keywords: artificial intelligence; machine learning; surgical robotics; computer vision; predictive analytics; surgical decision support; perioperative care; surgical outcomes; digital surgery
(This special issue belongs to the Section General Surgery)
The Athlete’s Heart in the Era of Precision Medicine: From Clinical Characterization to Personalized Risk
edited by and Lucrezia Netti
submission deadline 30 Jan 2027 | Viewed by 127 | Submission Open
Keywords: athlete’s heart; exercise prescription; cardiac remodeling; sports cardiology; risk stratification; arrhythmias
(This special issue belongs to the Section Cardiovascular Medicine)
The Current Status and Future Directions of Pancreatoduodenectomy and Pancreatectomy
edited by , and Somaiah Aroori
submission deadline 31 Jan 2027 | 5 articles | Viewed by 9107 | Submission Open
Keywords: pancreatic resection types; techniques and modifications; anastomotic techniques; open resection; minimally invasive surgery; laparoscopic resection; robotic resection; hybrid resection techniques; pancreatic resection post neoadjuvant treatment; lymphadenectomy; vascular resections; organ-sparing procedures; radicality; indications; complications
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Personalized Management of Abdominal Surgery and Complications
edited by Ioannis Mantzoros and
submission deadline 31 Jan 2027 | 3 articles | Viewed by 2981 | Submission Open
Keywords: personalized medicine; abdominal surgery; complications; emergency; innovative surgery
(This special issue belongs to the Section General Surgery)
Recent Advances and Future Perspectives of Subarachnoid Hemorrhage
edited by Alexandros Doukas and Athanasios K. Petridis
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2594 | Submission Open
Keywords: subarachnoid hemorrhage; neuromonitoring; neurocritical care; neurointerventions; neurointensive care
(This special issue belongs to the Section Clinical Neurology)
Orthopedic Trauma Surgery: Techniques, Challenges and Rehabilitation
edited by Julian Scherer
submission deadline 31 Jan 2027 | Viewed by 901 | Submission Open
Keywords: orthopedic trauma surgery; minimally invasive osteosynthesis; spinal trauma; polytrauma management; digital follow-up and rehabilitation
(This special issue belongs to the Section Orthopedics)
Innovations in Electrical Therapy for Heart Failure
edited by Zoltán Csanádi and
submission deadline 31 Jan 2027 | Viewed by 255 | Submission Open
Keywords: cardiac arrhythmias; atrial fibrillation; cardiac pacing; implantable cardioverter-defibrillators; cardiac resynchronization therapy; conduction system pacing; catheter ablation; arrhythmogenic disorders; heart failure; autonomic nervous system modulation
(This special issue belongs to the Section Cardiology)
New Insights on Pharmacologic and Non-Pharmacologic Therapy of Advanced Heart Failure
edited by
submission deadline 5 Feb 2027 | 1 articles | Viewed by 1065 | Submission Open
Keywords: advanced heart failure (AHF); mechanical circulatory support systems; heart transplantation (HTx); immunosuppression; cardiac allograft rejections
(This special issue belongs to the Section Cardiology)
Clinical Outcomes Improvement and Perioperative Management of Surgical Patients: 3rd Edition submission deadline 10 Feb 2027 | 7 articles | Viewed by 5984 | Submission Open
Keywords: clinical outcomes; surgery; quality; quality of life; quality improvement; postoperative; morbidity; postoperative care
(This special issue belongs to the Section General Surgery)
Clinical Advances in Pediatric Critical Care Medicine
edited by
submission deadline 10 Feb 2027 | 6 articles | Viewed by 5547 | Submission Open
Keywords: acute renal failure; acute respiratory failure; pediatric oncology; pediatric ICU; pediatric critical care medicine; multi-organ dysfunction
(This special issue belongs to the Section Clinical Pediatrics)
Surgical Management of Maxillofacial Fractures and Reconstruction of Facial Deformities
edited by , and Francesco Arcuri
submission deadline 10 Feb 2027 | 5 articles | Viewed by 4723 | Submission Open
Keywords: head and neck reconstruction; facial fractures; minimally invasive treatments; facial reconstruction; bioengineering in head and neck disorders; CAD/CAM in maxillo facial trauma and deformities
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Advancements and Future Directions in Clinical Psychosis submission deadline 10 Feb 2027 | 3 articles | Viewed by 4578 | Submission Open
Keywords: clinical psychosis; schizophrenia spectrum disorders; early detection of psychosis; treatment-resistant psychosis; long-term outcomes; personalized psychiatry; digital mental health; AI in psychiatry; neurocognitive interventions; psychosocial therapies; translational psychiatry; interdisciplinary mental health; psychosis clinical trials; innova-tive diagnostic tools
(This special issue belongs to the Section Mental Health)
Cardiac Arrest and Postcardiac Arrest Care: State of the Art and Future Directions
edited by and Soheil Saadat
submission deadline 10 Feb 2027 | 4 articles | Viewed by 3600 | Submission Open
Keywords: out-of-hospital cardiac arrest; cardiopulmonary resuscitation; postcardiac arrest syndrome; postcardiac arrest care; survival; neurologic outcomes
(This special issue belongs to the Section Emergency Medicine)
Pediatric Hearing Loss: Advances in Early Detection, Intervention and Family-Centered Care submission deadline 10 Feb 2027 | 2 articles | Viewed by 3487 | Submission Open
Keywords: pediatric hearing loss; early intervention; early identification of language and communication disorders; develop-mental language disorders; predictors of outcomes; newborn hearing screening; pediatric audiology
(This special issue belongs to the Section Otolaryngology)
Clinical and Diagnostic Strategies for Glioma Treatment
edited by and Egils Valeinis
submission deadline 10 Feb 2027 | 5 articles | Viewed by 2898 | Submission Open
Keywords: glioma; glioblastoma; astrocytoma; oligodendroglioma; IDH; neuro-oncology; neurosurgery; radiotherapy; neuropathology; diagnostics; treatment
(This special issue belongs to the Section Clinical Neurology)
Advances in Maternal–Fetal Medicine
edited by
submission deadline 10 Feb 2027 | 1 articles | Viewed by 1727 | Submission Open
Keywords: maternal–fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence
(This special issue belongs to the Section Obstetrics & Gynecology)
Diagnosis and Treatment of Pediatric Endocrine Disorders—Focus on Rare Conditions
edited by Sophia Sakka
submission deadline 10 Feb 2027 | Viewed by 1606 | Submission Open
Keywords: pediatric endocrinology; diabetes mellitus in children; bone metabolism disorders; clinical diagnosis; therapeutic strategies; skeletal dysplasias; rare endocrine conditions; pediatric type 1 diabetes; rickets management; genetic conditions; pediatric hormone therapy; achondroplasia
(This special issue belongs to the Section Endocrinology & Metabolism)
New Advances in Cardiovascular Diseases: The Cutting Edge—2nd Edition
edited by
submission deadline 10 Feb 2027 | 1 articles | Viewed by 458 | Submission Open
Keywords: cardiovascular disease (CVD); preventive cardiology; cardiac pharmacology; coronary artery disease (CAD); heart failure (HF); atrial fibrillation (AF); supraventricular and ventricular arrhythmias
(This special issue belongs to the Section Cardiovascular Medicine)
Cardiomyopathy: Diagnosis and Therapeutic Advances
edited by Ilaria Dentamaro and Annagrazia Cecere
submission deadline 10 Feb 2027 | Viewed by 410 | Submission Open
Keywords: cardiomiopathy; cardiac magnetic resonance (CMR); advanced echocardiography; heart failure; hypertrophic cardiomyopathy
(This special issue belongs to the Section Cardiology)
Pediatric Spinal Dysraphisms, Tethered Cord Syndrome and Scoliosis: Controversies, Recent Advances, and Future Challenges
edited by Taemin Oh
submission deadline 10 Feb 2027 | Viewed by 135 | Submission Open
Keywords: pediatric spine; scoliosis; cervical instability; spinal dysraphism; tethered cord syndrome; myelomeningocele; neural tube defects; spinal cord malformations; spinal column shortening
(This special issue belongs to the Section Clinical Neurology)
Male Sexual and Reproductive Health: Clinical Aspects, Metabolic Profile, Environmental Factors and Lifestyle: 2nd Edition
edited by
submission deadline 15 Feb 2027 | 7 articles | Viewed by 22719 | Submission Open
Keywords: male sexual dysfunction; reproductive health; erectile dysfunction; premature ejaculation; infertility; epidemiology; causes; diagnosis; treatments; environmental factors; lifestyle
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Diabetes Mellitus and Emerging Health Challenges: A Multidisciplinary Perspective
edited by Katarzyna A. Majewska and
submission deadline 15 Feb 2027 | 9 articles | Viewed by 16057 | Submission Open
Keywords: diabetes mellitus; type 1 diabetes; type 2 diabetes; diabetic complications; prediabetes; diabetes treatment; autoimmune diabetes
(This special issue belongs to the Section Endocrinology & Metabolism)
Periodontal Diseases and Systemic Health: Pathogenesis, Prevention and Management
edited by
submission deadline 15 Feb 2027 | 8 articles | Viewed by 13437 | Submission Open
Keywords: periodontitis; dental implants; systemic inflammation; diabetes and periodontal disease; cardiovascular implications; pregnancy and oral health; host immune responses; preventive dentistry; implant-prosthetic rehabilitation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advances in Gynecological Diseases (Second Edition)
edited by
submission deadline 15 Feb 2027 | 5 articles | Viewed by 5868 | Submission Open
Keywords: gynecology; women's health; mini-invasive surgery; laparoscopy; hysteroscopy; diagnostic imaging; gynecological oncology; endometriosis; new therapy; urogynecology; female healthcare
(This special issue belongs to the Section Obstetrics & Gynecology)
Thoracic Surgery: Current Practice and Future Directions: 2nd Edition
edited by
submission deadline 15 Feb 2027 | 4 articles | Viewed by 5336 | Submission Open
Keywords: NSCLC; mediastinum; thymoma; esophageal disease; immunotherapy; new technologies; minimally invasive surgery; VATS; RATS
(This special issue belongs to the Section Respiratory Medicine)
Gender Differences and Diversity in the Treatment of Gastric Cancer and Other Malignancies
edited by Claus Schildberg and Frank Meyer
submission deadline 15 Feb 2027 | 5 articles | Viewed by 4320 | Submission Open
Keywords: gastric cancer; other cancers; other treatment; gender differences; diversity; new challances
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Insights and Challenges into Cognitive and Mental Health in Older Adults
edited by
submission deadline 15 Feb 2027 | 1 articles | Viewed by 3539 | Submission Open
Keywords: clinical insights; cognitive and mental health; older adults; psychosomatic interventions; person-centered care
(This special issue belongs to the Section Mental Health)
Congenital Heart Diseases: Epidemiology, Treatment and Lifelong Support
edited by Sebastian Freilinger, , and Oliver Dewald
submission deadline 15 Feb 2027 | 5 articles | Viewed by 3199 | Submission Open
Keywords: congenital heart disease (CHD); adults with CHD; epidemiology; comorbidities; intervention; surgical treatment; psychological aspects; quality of life (QoL); risk factors; rehabilitation; health promotion; prevention; health literacy; physical activity; lifelong support
(This special issue belongs to the Section Cardiology)
Cardiovascular Disease Risk Assessment and Clinical Management submission deadline 15 Feb 2027 | 3 articles | Viewed by 2699 | Submission Open
Keywords: cardiovascular risk assessment; cardiovascular disease prevention; risk factor management; preventive cardiovascular medicine; conservative treatment; percutaneous coronary interventions; health communication strategies; public health intervention
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advancements in Foot and Ankle Surgery: 2nd Edition
edited by
submission deadline 15 Feb 2027 | 2 articles | Viewed by 1154 | Submission Open
Keywords: flat foot; hindfoot motion; diabetic foot; hallux valgus; foot infection; foot trauma
(This special issue belongs to the Section Orthopedics)
Current Challenges and Opportunities in Assisted Reproductive Technologies
edited by Andrea Milostić-Srb and
submission deadline 15 Feb 2027 | Viewed by 500 | Submission Open
Keywords: artificial reproductive technologies; ART; mental health effect on ART; IVF; AI in reproductive medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Patient Safety and Clinical Outcomes in Robotic-Assisted Microsurgery and Endoscopic Surgery
edited by Tetsuji Uemura
submission deadline 15 Feb 2027 | Viewed by 373 | Submission Open
Keywords: endoscopic surgery; reconstructive surgery; robotic-assisted microsurgery; advanced surgical technologies; patient safety
(This special issue belongs to the Section General Surgery)
Malocclusion: Orthodontic Treatment, Periodontal Health and Epidemiology
edited by Monika Elżbieta Machoy
submission deadline 15 Feb 2027 | Viewed by 123 | Submission Open
Keywords: malocclusion; orthodontic treatment; periodontal health; periodontology; gingival inflammation; reduced periodontal support; clear aligners; fixed appliances; alveolar bone; gingival phenotype; oral epidemiology; digital dentistry; CBCT; artificial intelligence; oral microbiome
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Dental Implantology: Clinical Updates and Perspectives—2nd Edition
edited by
submission deadline 16 Feb 2027 | 6 articles | Viewed by 13303 | Submission Open
Keywords: dental implantology; reconstructive surgery; biomaterials; tissue engineering; regenerative medicine; digital dentis-try; periimplantitis; peri-implant soft tissues
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Unraveling Myopia: Current Science, Clinical Impact, and Future Horizons
edited by Neeraj K Singh and Pablo De Gracia
submission deadline 19 Feb 2027 | 5 articles | Viewed by 15279 | Submission Open
Keywords: accommodation; contact lenses; ophthalmic lenses; myopia progression; epidemiology; myopia control interventions; pharmaceutical treatments; environmental and behavioral risk factors; imaging innovations in myopia
(This special issue belongs to the Section Ophthalmology)
Movement Analysis in Rehabilitation
edited by Paola Contessa
submission deadline 19 Feb 2027 | 4 articles | Viewed by 6644 | Submission Open
Keywords: clinical biomechanics; engineering methods; human movement; motor control; muscle force; musculoskeletal disorders; neuromuscular diseases; posture and balance; rehabilitation
(This special issue belongs to the Section Orthopedics)
A Holistic Approach to Management of Complications in Hemodialysis
edited by
submission deadline 19 Feb 2027 | 1 articles | Viewed by 723 | Submission Open
Keywords: hemodialysis; complications; holistic care management; quality of life; well-being malnutrition; hypotension; cardiovascular diseases; inflammation; vascular access
(This special issue belongs to the Section Nephrology & Urology)
Alzheimer’s Disease and Related Disorders: Recent Advances in Prevention, Diagnosis and Therapy submission deadline 20 Feb 2027 | 4 articles | Viewed by 15203 | Submission Open
Keywords: cognition; prodromal; Alzheimer’s; Alzheimer; dementia; mild cognitive impairment; mild decline in cognition; disease-modifying; amyloid; tau; neuroinflammation; biomarkers; neuroimaging; PET; PET/CT; PET/MRI
(This special issue belongs to the Section Clinical Neurology)
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