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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ovarian Reserve in Endometriosis: Assessment, Preservation and Reproductive Outcomes
edited by Angelos Daniilidis and
submission deadline 20 Jul 2027 | Viewed by 54 | Submission Open
Keywords: endometriosis; ovarian endometrioma; ovarian reserve; anti-Müllerian hormone; antral follicle count; fertility preservation; ovarian cystectomy; assisted reproductive technology
(This special issue belongs to the Section Obstetrics & Gynecology)
Reconstructive and Clinical Management of Female Genital Conditions
edited by
submission deadline 20 Jul 2027 | Viewed by 47 | Submission Open
Keywords: female genital conditions; female genital mutilation; FGM/C; reconstructive surgery; clitoral re-construction; women's health; global surgery; sexual health; patient-reported outcomes
(This special issue belongs to the Section Obstetrics & Gynecology)
Recent Advances in Cardiovascular Health: From Research to Clinical Practice
edited by
submission deadline 20 Jul 2027 | Viewed by 46 | Submission Open
Keywords: cardiovascular disease; cardiovascular health; cardiovascular prevention; cardiovascular risk; coronary artery disease; heart failure; cardiovascular imaging
(This special issue belongs to the Section Cardiovascular Medicine)
Infectious, Cardiovascular, Urological and Metabolic Issues After Kidney Transplantation
edited by Emma Aitken
submission deadline 20 Jul 2027 | Viewed by 45 | Submission Open
Keywords: kidney transplantation; cardiovascular; infections; urology; metabolic
(This special issue belongs to the Section Nephrology & Urology)
Spine Neurosurgery: Clinical Advances and Future Directions
edited by
submission deadline 20 Jul 2027 | Viewed by 43 | Submission Open
Keywords: minimally invasive spine surgery; endoscopic spine surgery; robotic spine surgery; surgical navigation; augmented reality; artificial intelligence; machine learning; motion preservation; clinical outcomes
(This special issue belongs to the Section Clinical Neurology)
Infectious Diseases and Immunocompromised Hosts
edited by
submission deadline 20 Jul 2027 | Viewed by 42 | Submission Open
Keywords: immunocompromised hosts; infectious diseases; clinical epidemiology; opportunistic infections; risk factors; anti-microbial therapy; clinical outcomes
(This special issue belongs to the Section Infectious Diseases)
Thoracic Radiotherapy in the Immunotherapy Era: Current Challenges and Future Directions submission deadline 20 Jul 2027 | Viewed by 41 | Submission Open
Keywords: thoracic radiotherapy; lung cancer; immunotherapy; radiation-induced lung injury; interstitial lung disease; treatment sequencing; particle therapy; oligometastatic disease; radiation toxicity; precision radiotherapy
(This special issue belongs to the Section Oncology)
Advanced Hysteroscopic Technology for Gynecological Disease: 2nd Edition submission deadline 20 Jul 2027 | Viewed by 41 | Submission Open
Keywords: hysteroscopy; new technology; therapy; mini-invasive approach; laser; diagnosis; outcomes
(This special issue belongs to the Section Obstetrics & Gynecology)
Helicobacter pylori Infection in the Era of Precision Medicine: From Antimicrobial Resistance to Artificial Intelligence and Gastric Cancer Prevention
edited by
submission deadline 20 Jul 2027 | Viewed by 37 | Submission Open
Keywords: Helicobacter pylori; eradication; gastric cancer; atrophic gastritis; intestinal metaplasia; gastric acid inhibition; microbiome; endoscopic submucosal dissection
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Clinical Neurosonology: From Point-of-Care Ultrasound to Therapeutic Application
edited by and Giovanni Malferrari
submission deadline 20 Jul 2027 | Viewed by 35 | Submission Open
Keywords: neurosonology; point-of-care ultrasound; Neuro-POCUS; Stroke-POCUS; bedside ultrasound; transcranial Doppler; transcranial color-coded duplex; acute ischemic stroke; neurocritical care; focused cardiac ultrasound; orbital ultrasound; intracranial pressure; focused ultrasound; blood–brain barrier; intraoperative ultrasound; artificial intelligence; multimodal ultrasound
(This special issue belongs to the Section Clinical Neurology)
Stroke and Neurological Disorders: Bridging Clinical Advances, Rehabilitation Gaps, and Systemic Challenges
edited by , Robert Ślusarz and Renata Jabłońska
submission deadline 20 Jul 2027 | Viewed by 35 | Submission Open
Keywords: stroke; neurological disorders; advances in neurological care; neurorehabilitation and functional recovery; integrated and multidisciplinary care; health system challenges and disparities
(This special issue belongs to the Section Clinical Neurology)
Cataract and Refractive Surgery and Intraocular Lens Implantation: Clinical Advances and Perspectives: 2nd Edition
edited by
submission deadline 20 Jul 2027 | Viewed by 35 | Submission Open
Keywords: cataract surgery; intraocular lens; LASIK; KLEx; refractive surgery
(This special issue belongs to the Section Ophthalmology)
Periprosthetic Joint Infection in Hip and Knee Arthroplasty: Current Challenges, Controversies and Clinical Outcomes
edited by
submission deadline 20 Jul 2027 | Viewed by 34 | Submission Open
Keywords: periprosthetic joint infection; knee and hip arthroplasty; revision arthroplasty; fracture; osteoporosis; bone; musculoskeletal imaging
(This special issue belongs to the Section Orthopedics)
Clinical Advances in Cardiac Imaging: CT, MRI, Nuclear, and Ultrasound Innovations
edited by
submission deadline 20 Jul 2027 | Viewed by 32 | Submission Open
Keywords: cardiovascular imaging; cardiac magnetic resonance; cardiac computed tomography; echocardiography; nuclear cardiology; multimodality imaging; artificial intelligence
(This special issue belongs to the Section Cardiology)
Current Trends and Future Perspectives in Cardiovascular Imaging
edited by Niya Mileva
submission deadline 20 Jul 2027 | Viewed by 31 | Submission Open
Keywords: cardiovascular imaging; multimodality imaging; echocardiography; cardiac computed tomography; cardiac magnetic resonance; nuclear imaging
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advances and Challenges in Abdominal Imaging and Intervention submission deadline 20 Jul 2027 | Viewed by 29 | Submission Open
Keywords: abdominal imaging; computed tomography (CT); magnetic resonance imaging (MRI); emergency medicine; interventional radiology; multidisciplinary management; artificial intelligence in medicine; ultrasound
(This special issue belongs to the Section Nuclear Medicine & Radiology)
The Complex Interplay Between Physical Activity, Sleep, Diet, and Obesity: Clinical Insights for Treatment and Prevention: 2nd Edition submission deadline 20 Jul 2027 | Viewed by 27 | Submission Open
Keywords: body mass; body composition; nutrition; sleep patterns; weight management; lifestyle interventions; sedentary behavior; adiposity; obesity prevention; dietary habits
(This special issue belongs to the Section Endocrinology & Metabolism)
Understanding Vulnerability and Clinical Heterogeneity in Addiction: From Risk Factors to Clinical Management submission deadline 20 Jul 2027 | Viewed by 27 | Submission Open
Keywords: addiction; behavioral addictions; reward processing; decision-making; emotion regulation; impulsivity; individual differences; clinical heterogeneity; neurocognitive mechanisms; psychophysiology; psychopathology; clinical out-comes; treatment response
(This special issue belongs to the Section Mental Health)
New Clinical Advances in the Management of Crohn's Disease and Ulcerative Colitis
edited by Agata Michalak
submission deadline 20 Jul 2027 | Viewed by 26 | Submission Open
Keywords: inflammatory bowel disease; Crohn’s disease; ulcerative colitis; inflammation; markers; epithelial integrity
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current and Emerging Diagnosis and Treatment Perspectives in Vestibular Disorders submission deadline 20 Jul 2027 | Viewed by 25 | Submission Open
Keywords: vestibular disorders; BPPV; vHIT; vestibular diagnosis; vestibular rehabilitation; virtual reality; vestibular schwan-noma; vestibular neuritis; VOR testing; bedside vestibular evaluation; meniere’s disease; vestibular neuropathy
(This special issue belongs to the Section Otolaryngology)
Hot Topics and New Insights in the Diagnosis and Treatment of Pancreatic Diseases
edited by Guido Alsfasser
submission deadline 20 Jul 2027 | Viewed by 19 | Submission Open
Keywords: artificial intelligence; robotic surgery; pancreatic disease; diagnostic challenges; intensive care unit; management of complications
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Individualized and Multimodal Management of ACL Injuries and Associated Knee Lesions
edited by Nicolas Bouguennec
submission deadline 20 Jul 2027 | Viewed by 19 | Submission Open
Keywords: anterior cruciate ligament; associated knee injuries; individualized treatment; ACL reconstruction; ACL repair; rotational instability; rehabilitation; return to sport
(This special issue belongs to the Section Sports Medicine)
Pancreatic Surgery: Current Advances and Future Challenges
edited by
submission deadline 20 Jul 2027 | Viewed by 18 | Submission Open
Keywords: pancreatic surgery; pancreatic tumors; peri-ampullary tumors; robotic surgery; pancreas transplantation; surgical out-comes
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Aesthetic Reconstructive Microsurgery and Robotic Applications
edited by
submission deadline 20 Jul 2027 | Viewed by 16 | Submission Open
Keywords: aesthetic reconstructive microsurgery; robotic microsurgery; facial reconstruction;; facial palsy
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Theranostics and Radiopharmaceutical Therapy in Oncology: Clinical and Translational Advances submission deadline 22 Jul 2027 | Viewed by 40 | Submission Open
Keywords: theranostics; radioligand therapy; radiopharmaceuticals; personalized dosimetry; radioimmunotherapy; molecular imaging
(This special issue belongs to the Section Oncology)
Navigating Pregnancy and Its Complications: Challenges and Innovations in Maternal–Fetal Medicine (Second Edition) submission deadline 25 Jul 2027 | Viewed by 37 | Submission Open
Keywords: pregnancy; obstetrics; gestational diabetes; high risk; preeclampsia; labor; delivery; hypertension; hemorrhage; embryo; novel therapeutics
(This special issue belongs to the Section Obstetrics & Gynecology)
Current Concept of Cardio-Renal-Metabolic Interactions submission deadline 25 Jul 2027 | Viewed by 35 | Submission Open
Keywords: cardio-renal syndrome; cardio-kidney-metabolic syndrome; acute kidney injury; chronic kidney disease; dialysis; heart failure
(This special issue belongs to the Section Cardiovascular Medicine)
Liver Transplantation: A Multidisciplinary Perspective on Advances in Perioperative Care
edited by and Ji-Hye Kwon
submission deadline 25 Jul 2027 | Viewed by 23 | Submission Open
Keywords: liver transplantation; hepatobiliary surgery; transplant pathology; perioperative anesthesia; coagulation manage-ment; graft rejection; ischemia–reperfusion injury; living donor liver transplantation; machine perfusion; multidis-ciplinary transplant care
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Obesity and Metabolic Dysfunction in Endocrine Disorders: Latest Developments, Challenges and Future Perspectives submission deadline 28 Jul 2027 | Viewed by 60 | Submission Open
Keywords: obesity; metabolic dysfunction; metabolic complications; endocrine disorders; adipose tissue dysfunction
(This special issue belongs to the Section Endocrinology & Metabolism)
Multiple Sclerosis and Demyelinating Disorders: Recent Clinical Advances and Future Perspectives
edited by and Smaranda Maier
submission deadline 28 Jul 2027 | Viewed by 28 | Submission Open
Keywords: demyelinating disease; multiple sclerosis; neuromyelitis optica spectrum disorder; disease modifying treatments; high efficacy therapies; quality of life
(This special issue belongs to the Section Clinical Neurology)
Insights into Urological Surgery: Evolving Practices, Trends, and Emerging Challenges submission deadline 30 Jul 2027 | Viewed by 348 | Submission Open
Keywords: urology; urological surgery; urological oncology; uro-technology; quality of life
(This special issue belongs to the Section Nephrology & Urology)
Musculoskeletal Sports Injuries: From Prevention to Performance
edited by Andrew J. Hall
submission deadline 30 Jul 2027 | Viewed by 47 | Submission Open
Keywords: musculoskeletal injury; sports injury; injury prevention; return to sport; rehabilitation; athlete health; sports medicine; performance medicine; orthopaedics; sports
(This special issue belongs to the Section Sports Medicine)
Septic Complications in Cardiovascular Surgery and Interventional Cardiology: Current Challenges and Future Directions
edited by Francesco Onorati and Giovanni Mariscalco
submission deadline 30 Jul 2027 | Viewed by 43 | Submission Open
Keywords: native valve endocarditis; prosthetic endocarditis; endocarditis of cardiac implantable electronic devices (CIED); VAD endocarditis; TAVI endocarditis; vascular prosthetic infections; endovascular prosthetic infections; surgical site infec-tions; mediastinitis; sepsis; septic complications; early recovery after cardiovascular surgery (ERAS); critical care after cardiovascular surgery
(This special issue belongs to the Section Cardiology)
Advances in Perioperative Anesthesia and Pain Management
edited by
submission deadline 30 Jul 2027 | Viewed by 25 | Submission Open
Keywords: perioperative medicine; anesthesia; airway management; difficult airway; awake intubation; pain management; regional anesthesia; trauma anesthesia; critically ill patients; hemodynamic optimization; patient blood management; coagulation; blood transfusion; obesity; perioperative outcomes
(This special issue belongs to the Section Anesthesiology)
Ageing and Well-Being in Transplantology: Clinical Progress and Quality of Life
edited by , Leszek Domański and Krzysztof Mucha
submission deadline 31 Jul 2027 | Viewed by 42 | Submission Open
Keywords: solid organ transplantation ; lifestyle ; medicine ; healthy ageing ; healthspan ; longevity ; frailty ; sarcopenia ; nutrition ; physical activity ; rehabilitation ; cardiometabolic health ; obesity ; behaviour change ; quality of life ; patient-reported outcomes
(This special issue belongs to the Section Nephrology & Urology)
Contemporary Plastic and Reconstructive Surgery: Bridging Reconstruction and Aesthetics
edited by
submission deadline 10 Aug 2027 | Viewed by 48 | Submission Open
Keywords: plastic surgery; reconstructive surgery; aesthetic surgery; microsurgery; regenerative medicine; surgical innovation; patient-centred outcomes
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Integrating Chemotherapy and Immunotherapy in the Clinical Management of Urologic Oncology
edited by and Andrea Gallioli
submission deadline 17 Aug 2027 | Viewed by 24 | Submission Open
Keywords: biomarkers; immunotherapy; chemotherapy; cisplatin eligible; cisplatin inheligible patients; complete response
(This special issue belongs to the Section Oncology)
Clinical Advances in Inflammatory Bowel Disease: From Diagnosis to Treatment submission deadline 20 Aug 2027 | 1 articles | Viewed by 642 | Submission Open
Keywords: inflammatory bowel disease; Crohn’s disease; ulcerative colitis; diagnosis; biomarkers; endoscopy; imaging; disease monitoring; biologics; advanced therapies; small molecules; personalized medicine; surgery; extraintestinal manifestations; real-world evidence; treatment optimization
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Latest Advances in Traumatic Brain Injury
edited by Jeffrey David Lewine
submission deadline 20 Aug 2027 | Viewed by 91 | Submission Open
Keywords: traumatic brain injury; neurotrauma; rehabilitation; clinical management TBI
(This special issue belongs to the Section Brain Injury)
Evidence-Based Minimally Invasive Spine Surgery: Techniques, Outcomes, and Innovations
edited by Sang-il Kim
submission deadline 20 Aug 2027 | Viewed by 88 | Submission Open
Keywords: minimally invasive spine surgery; full-endoscopic spinal surgery; TLIF; LLIF; OLIF; robotic-assisted spine surgery; intraoperative navigation; augmented reality; enhanced recovery after surgery (ERAS)
(This special issue belongs to the Section Orthopedics)
Muscle Health in Spine Surgery: From Risk Stratification and Surgical Optimization to Functional Recovery
edited by Kyung-Chung Kang and
submission deadline 20 Aug 2027 | Viewed by 38 | Submission Open
Keywords: muscle health; sarcopenia; paraspinal muscle; spine surgery; spinal alignment; minimally invasive surgery; rehabilitation; functional recovery
(This special issue belongs to the Section Orthopedics)
Clinical Challenges in Meibomian Gland Dysfunction and Dry Eye Disease
edited by
submission deadline 20 Aug 2027 | Viewed by 31 | Submission Open
Keywords: dry eye; meibomian gland; meibomian gland dysfunction; ophthalmic surgery; ocular surface
(This special issue belongs to the Section Ophthalmology)
Burn Wounds: Clinical Advances and Future Perspectives
edited by Denis Ehrl and Moritz Billner
submission deadline 20 Aug 2027 | Viewed by 25 | Submission Open
Keywords: burns; burn wound management; biomaterials; burn depth assessment; dermal regeneration templates; skin substitutes; enzymatic debridement; autologous skin cell suspension; keratinocytes; burn wound reconstruction; wound healing
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Benefits of Outpatient or One-Day Surgery in Surgical Procedures
edited by Laura Mora-Lopez
submission deadline 20 Aug 2027 | Viewed by 22 | Submission Open
Keywords: ambulatory surgery; one-day surgery; major abdominal surgery; robotic surgery; minimally invasive surgery
(This special issue belongs to the Section General Surgery)
Precision Obstetrics for Pregnancy Complications: Biomarkers, Prediction and Management
edited by Isauro Rogelio Monfort-Ortiz
submission deadline 20 Aug 2027 | Submission Open
Keywords: precision obstetrics; preeclampsia; preterm birth; biomarkers; maternal-fetal medicine; pregnancy complications; risk stratification; innovative monitoring
(This special issue belongs to the Section Obstetrics & Gynecology)
Selected Papers from the 4th International Online Conference on Clinical Medicine
edited by and
submission deadline 25 Aug 2027 | Viewed by 87 | Submission Open
Keywords: immunology and rheumatology; infectious diseases; oncology; AI in clinical radiology and nuclear medicine; metabolism and chronic diseases; epidemiology and public health; cardiovascular medicine; clinical neurology
Spine Surgery: Current Updates and Future Challenges
edited by Antonio Meola, and Leonello Tacconi
submission deadline 30 Aug 2027 | Viewed by 111 | Submission Open
Keywords: spinal surgery; minimally invasive spine surgery; spinal disorders; spinal complications; clinical outcomes; robotic spine surgery; artificial intelligence; spinal navigation; spinal instrumentation; spine innovation
(This special issue belongs to the Section Clinical Neurology)
Exercise, Injury, Disease and Rehabilitation: Clinical Perspectives in Sports Medicine
edited by and
submission deadline 31 Aug 2027 | Viewed by 52 | Submission Open
Keywords: sports medicine; exercise therapy; sports injury; rehabilitation; injury prevention; exercise prescription; return to sport; chronic disease; personalized medicine; digital health
(This special issue belongs to the Section Sports Medicine)
Rheumatic Pain: From Mechanisms to Clinical Management submission deadline 20 Sep 2027 | Viewed by 172 | Submission Open
Keywords: rheumatic diseases; musculoskeletal pain; chronic pain; inflammatory pain; nociceptive pain; nociplastic pain; neuropathic pain; central sensitization; fibromyalgia; osteoarthritis; rheumatoid arthritis; spondyloarthritis; pain measurement; patient-reported outcome measures; pain management
(This special issue belongs to the Section Immunology & Rheumatology)
Perioperative Management in Thoracic Surgery: Perspectives and Advances
edited by Filippo Lococo and
submission deadline 20 Sep 2027 | Viewed by 48 | Submission Open
Keywords: perioperative care; thoracic surgery; enhanced recovery after surgery (ERAS); minimally invasive thoracic surgery; neoadjuvant immunotherapy; prehabilitation and risk stratification
(This special issue belongs to the Section Respiratory Medicine)
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