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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research and Treatment of Prostate Cancer

edited by

Manuela Zavatti

and

Sandra Marmiroli

submission deadline 20 Oct 2025 | 3 articles | Viewed by 6824 | Submission Open

Keywords: prostate cancer; PI3K/AKT pathway; resistance mechanism; androgen receptor; MAPK

(This special issue belongs to the Section Molecular Oncology)

MicroRNA and Non-Coding RNA: From Basic Research to Potential Clinical Application

edited by

Erika Cione

submission deadline 20 Oct 2025 | 5 articles | Viewed by 6731 | Submission Open

Keywords: miRNA; ncRNA; biomarkers; therapeutics; microarray; NGS

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Molecular Insights into Antimicrobial Photo-Treatments

edited by Pietro Delcanale

submission deadline 20 Oct 2025 | 3 articles | Viewed by 6652 | Submission Open

Keywords: photodynamic inactivation; photo-thermal therapy; photosensitization; antimicrobials; reactive oxygen species; photo-treatments; antibiotic resistance; singlet oxygen; antivirals

(This special issue belongs to the Section Molecular Microbiology)

Recent Advances in RNA Drug Development

edited by Hidenori Tani

submission deadline 20 Oct 2025 | 3 articles | Viewed by 6609 | Submission Open

Keywords: RNA therapeutics; drug development; antisense oligonucleotides; siRNA; miRNA; aptamers; CRISPR-Cas9; delivery systems; clinical applications; emerging technologies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mitochondrial and Energy Metabolic Function in Heart and Skeletal Muscle

edited by Yoshitake Cho

submission deadline 20 Oct 2025 | 1 articles | Viewed by 6311 | Submission Open

Keywords: heart; skeletal muscle; metabolism; glucose; mitochondria; metabolic disorder

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Extracellular Vesicles: From Molecular Mechanisms to Therapeutic Applications

edited by Jung-Hyun Lee

submission deadline 20 Oct 2025 | 6 articles | Viewed by 6134 | Submission Open

Keywords: extracellular vesicles; intercellular communications; biomarkers; drug delivery systems

(This special issue belongs to the Section Biochemistry)

Exosomes—3rd Edition

edited by

Abdelnaby Khalyfa

submission deadline 20 Oct 2025 | 4 articles | Viewed by 6065 | Submission Open

Keywords: extracellular vesicles (EVs); exosomes; cancer; sleep cardiovascular diseases; lung disease and upper airways; obesity; sleep and end-organ morbidity

(This special issue belongs to the Section Molecular Biology)

New Advances in Epigenetics and Epigenomics

edited by Vicki Maltby

submission deadline 20 Oct 2025 | 4 articles | Viewed by 6051 | Submission Open

Keywords: epigenetics; epigenomics; multi-omics; epitranscriptomics; single cell

(This special issue belongs to the Section Molecular Genetics and Genomics)

Novel Extracellular Vesicle-Based Therapy for Central Nervous System Diseases

edited by Andrea Cabrera-Pastor

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5802 | Submission Open

Keywords: extracellular vesicles (EVs); exosomes; therapy; CNS disorders; neuroinflammation; signal transduction; mechanism; interorgan crosstalk; biomarker; EVs from MSCs; drug delivery

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Research in Plant–Fungus Interactions: Second Edition

edited by

Jiangyun Gao

submission deadline 20 Oct 2025 | 3 articles | Viewed by 5799 | Submission Open

Keywords: plant– fungus interactions; symbiotic association; endophytes; plant conservation; mycorrhizal symbioses

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Cancer Invasion and Metastasis

edited by

Zbigniew Baster

submission deadline 20 Oct 2025 | 5 articles | Viewed by 5498 | Submission Open

Keywords: cancer; cancer invasion; metastasis; tumor microenvironment; molecular basis of cancer; immunotherapy; cell motility; cancer genetics; cancer development

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Brain Plasticity in Health and Disease

edited by

Pawan Faris

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5377 | Submission Open

Keywords: brain plasticity; brain structure and function; cerebral cortex; cerebellum; neurological disorders; neuropsychiatric disorders; neurophysiology; computational modeling; brain imaging; Neuroplasticity

(This special issue belongs to the Section Molecular Neurobiology)

Metabolic Dysfunction-Associated Steatotic Liver Disease: From Basic Science to Therapy

edited by

Łukasz Bułdak

submission deadline 20 Oct 2025 | 4 articles | Viewed by 5338 | Submission Open

Keywords: MASLD; liver steatosis; steatohepatitis; liver cirrhosis; hepatocellular carcinoma; in vivo; in vitro; therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cellular Research in Pregnancy-Related Complications, 2nd Edition

edited by

Regina Komsa-Penkova

submission deadline 20 Oct 2025 | 2 articles | Viewed by 5180 | Submission Open

Keywords: pregnancy loss/miscarriage; pregnancy complications; pre-eclampsia; maternal– placental– fetal interactions; trophoblast; immune cells; immune tolerance; red blood cells; oxidative stress; blood and fetal proteins; DNA; RNA; stem cells

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights into Liver Biology and Disease Pathogenesis: Shedding Light on Novel Diagnostic and Therapeutic Approaches

edited by

Thiago Almeida Pereira

submission deadline 20 Oct 2025 | 3 articles | Viewed by 5133 | Submission Open

Keywords: liver molecular biology; novel biomarkers; liver regeneration; liver repair; liver carcinogenesis; brain– gut– liver axis; novel therapeutic targets; molecular diagnostic tools; host– pathogen interactions; novel in vitro and in vivo models of liver diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research and Treatment in Multiple Sclerosis

edited by Nada Starčević Čizmarević and

Borut Peterlin

submission deadline 20 Oct 2025 | 3 articles | Viewed by 5081 | Submission Open

Keywords: multiple sclerosis; neuroinflammation; neurodegeneration; genetics; molecular research; biomarkers; neuroimaging; therapy

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Cancer and Molecular Imaging

edited by Mi-Ae Park

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4771 | Submission Open

Keywords: molecular imaging; radiology; cancer detection; precision medicine; cancer mechanisms

(This special issue belongs to the Section Molecular Biology)

Design, Synthesis, and Bioapplications of Multifunctional Materials

edited by

Raluca Nicoleta Darie-Nita

and

Anamaria Irimia

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4693 | Submission Open

Keywords: bioactivity; biodegradability; polymers; composite materials; (nano)structured materials; packaging; biological and biomedical materials

(This special issue belongs to the Section Materials Science)

Cell Motility and Its Underlying Cellular and Molecular Mechanisms

edited by

Maria Giulia Lionetto

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4621 | Submission Open

Keywords: cell motility; cell migration; cytoskeleton; adhesion; signaling; imaging; microscopy; molecular biology

(This special issue belongs to the Section Biochemistry)

Biomarkers in Cancer Immunology

edited by

Wioletta Olejarz

submission deadline 20 Oct 2025 | 1 articles | Viewed by 4615 | Submission Open

Keywords: immunotherapy; adoptive cell transfer; CAR-T cells; immune checkpoint inhibitors; tumor microenvironment; extracellular vesicles; biomarkers; miRNA; DNA

(This special issue belongs to the Section Molecular Immunology)

Ion Channels as a Potential Target in Pharmaceutical Designs 2.0

edited by

Sheng-Nan Wu

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4568 | Submission Open

Keywords: ion currents; current kinetics; gating properties; voltage-dependent hysteresis; frequency-dependent regulation; small-molecule modulator

(This special issue belongs to the Section Molecular Biology)

The Role of Heat Shock Proteins: From Molecular Mechanisms to Therapeutics: 2nd Edition

edited by

Gregory Blatch

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4533 | Submission Open

Keywords: heat shock proteins; molecular chaperones; co-chaperones; protein folding; chronic diseases; infectious diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Macrophage Polarization: Learning to Manage It (4th Edition)

edited by

Nadia Lampiasi

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4448 | Submission Open

Keywords: macrophages; macrophage plasticity; macrophage polarization; innate immunity; IFN-γ ; TNF-α ; immunomodulators; diseases; homeostasis; inflammation; cancer

(This special issue belongs to the Section Molecular Immunology)

Heart Failure: From Molecular Basis to Therapeutic Strategies

edited by

Michele Ciccarelli

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4379 | Submission Open

Keywords: heart failure; cardiac metabolism; mitochondria; inflammatory pathway; neurohormonal system; therapeutical strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Research on Novel Lipid-Based Nano Drug Delivery Systems

edited by

Eder Lilia Romero

submission deadline 20 Oct 2025 | 1 articles | Viewed by 4280 | Submission Open

Keywords: lipids; nanoparticle; nanovesicle; algae; archaea; plant; bacteria; natural product

(This special issue belongs to the Section Molecular Pharmacology)

Chronic Kidney Disease: The State of the Art and Future Perspectives

edited by Alberto Rosati

submission deadline 20 Oct 2025 | 3 articles | Viewed by 4211 | Submission Open

Keywords: glomerulonephritis; chronic kidney disease; prevention; screening; cardiovascular mortality; patient outcomes; CKD progression

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Skin Diseases: 3rd Edition

edited by

Naoko Kanda

submission deadline 20 Oct 2025 | 2 articles | Viewed by 4103 | Submission Open

Keywords: infection; inflammation; molecular; neoplasm; pathogenesis; skin diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Research on Cancer Biology and Therapeutics: Third Edition

edited by

Rafael Coveñas Rodríguez

submission deadline 20 Oct 2025 | 4 articles | Viewed by 4052 | Submission Open

Keywords: antiangiogenic; anticancer therapy; antimetastatic; apoptosis; antiproliferative; cancer; peptides; signaling molecules; transcription factors; tumor

(This special issue belongs to the Section Molecular Oncology)

Editorial Board Members’ Collection Series: “Selenium and Sulfur Chemistry”

edited by

Claudio Santi

and

Narimantas K. Cenas

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3879 | Submission Open

Keywords: selenium; sulfur; redox; catalysis; selenoproteins; green chemistry; materials; stereoselective synthesis

(This special issue belongs to the Section Biochemistry)

DNA Damage in Neurological Disorders: Etiological and Therapeutical Aspects

edited by Tam Quach, Ilaria Palmisano and Anne-Marie Duchemin

submission deadline 20 Oct 2025 | 1 articles | Viewed by 3854 | Submission Open

Keywords: neurological disorders; peripheral neuropathies; DNA damage; epigenetic dynamism; 3D chromatin organization/remodeling; therapeutic targets for DNA repair

(This special issue belongs to the Section Molecular Neurobiology)

Protein Biosensors

edited by

Antonio Varriale

and

Maria Staiano

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3801 | Submission Open

(This special issue belongs to the Section Biochemistry)

Zebrafish as a Model for Biomedical Studies—2nd Edition

edited by

Pierre-Olivier Angrand

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3652 | Submission Open

Keywords: zebrafish; cancer; metabolic diseases; neurological disorders; infectious diseases; xenografts; drug discovery

(This special issue belongs to the Section Molecular Biology)

Hormone/Receptor System in Human Diseases

edited by

Elena Zocchi

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3620 | Submission Open

Keywords: characteristics of hormones; mechanisms of hormone action; structure; subunits and complexes of receptors; receptor function; expression and regulation; hormone/receptor signaling; interactions between receptors and hormones

(This special issue belongs to the Section Molecular Pharmacology)

Pathophysiology and Pharmacology in Psychiatry

edited by

Galila Agam

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3590 | Submission Open

Keywords: psychiatric disorders; mental health; pathophysiology; neuropsychopharmacology; brain

(This special issue belongs to the Section Molecular Neurobiology)

Small Cell Lung Cancer Entering the Sphere of Personalized Treatment

edited by

Anna Grenda

, Michał Szczyrek and Izabela Chmielewska

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3537 | Submission Open

Keywords: small cell lung cancer; SCLC; pathological subtypes; molecular subtypes; DNA; RNA; NGS; next-generation sequencing transcriptome; mutations; molecular analysis

(This special issue belongs to the Section Molecular Oncology)

Recent Advances in Photocatalysis: An Innovation in Catalysis

edited by

Andreea L. Chibac-Scutaru

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3496 | Submission Open

Keywords: semiconducting nanostructures; photocatalyst immobilized on substrates; hybrid composites; metal-free photocatalyst; photocatalysis mechanism; pollutant removal; hydrogen production; organic synthesis

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Extracellular Vesicles: The Biology and Therapeutic Applications, 2nd Edition

edited by

Tamás Visnovitz

submission deadline 20 Oct 2025 | 1 articles | Viewed by 3434 | Submission Open

Keywords: extracellular vesicles (EVs); exosomes; release; uptake; bio-distribution; methods; biomarkers; therapeutic applications

(This special issue belongs to the Section Molecular Biology)

Oxidation in Human Health and Disease

edited by

Isabel Fort

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3415 | Submission Open

Keywords: oxidative stress; oxidative balance; biochemical markers; reactive oxygen species TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Immunology)

Molecular Aspects of Cartilage Biology

edited by

Michela Geminiani

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3364 | Submission Open

Keywords: cartilage biology; tissue regeneration; molecular mechanisms; chondrocytes; cartilage disorders; therapeutic interventions; biomaterials

(This special issue belongs to the Section Molecular Biology)

Plant Resilience: Insights into Abiotic and Biotic Stress Adaptations

edited by

Xujun Zhu

submission deadline 20 Oct 2025 | 4 articles | Viewed by 3364 | Submission Open

Keywords: plants; basis of life; environmental stress; complex responses; molecular mechanisms; abiotic and biotic stress adaptations

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Genetics in Ovarian Cancer

edited by

Bruna Scaggiante

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3257 | Submission Open

Keywords: chemotherapy resistance; differential gene expression; genomic structural variation; ovarian cancer mutations; ovarian cancer metastasis; ovarian cancer treatment; novel molecular targets

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Mechanism in Cardiovascular Pathology

edited by Andrea Marzullo

submission deadline 20 Oct 2025 | 3 articles | Viewed by 3241 | Submission Open

Keywords: cardiovascular diseases; molecular biology; sudden death; cardiomyopathies; heart failure; coronary artery diseases; pericarditis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Paradox of Salmonella Survival and Host Defense Strategies

edited by

John Hwa Lee

and Amal Senevirathne

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3231 | Submission Open

Keywords: Salmonella; Salmonella serovars; virulence factors; host immune response; human health; animal health and poductivity; infection models

(This special issue belongs to the Section Molecular Microbiology)

Bioprinting: Progress and Challenges

edited by

Rui Vitorino

submission deadline 20 Oct 2025 | 1 articles | Viewed by 3197 | Submission Open

Keywords: advances in 3D bioprinting technologies; biomaterials for bioprinting; bioprinting applications in tissue engineering and regenerative medicine; cellular and molecular interactions in bioprinted constructs; bio-printed organ and tissue models for disease research

(This special issue belongs to the Section Materials Science)

The Role of Extracellular Matrix Proteins in Pathogenesis: 2nd Edition

edited by

Davide Raineri

submission deadline 20 Oct 2025 | 6 articles | Viewed by 3186 | Submission Open

Keywords: extracellular matrix proteins; autoimmune disease; cancer; cardiovascular diseases; inflammation; chronic diseases; human diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neuroprotective Effects of Food Ingredients

edited by

Elena Ibáñez

and

Alejandro Cifuentes

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3182 | Submission Open

Keywords: neuroprotection; Parkinson; Alzheimer; bioactive compounds; agri-food by-products; chemical characterization; foodomics; metabolomics; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research in Rheumatoid Arthritis

edited by Ângelo Calado

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3074 | Submission Open

Keywords: rheumatoid arthritis; synovium; autoimmunity; rheumatology; omics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Screening and Identification of Crop Abiotic Stress Tolerance Functional Genes

edited by

Liezhao Liu

submission deadline 20 Oct 2025 | 4 articles | Viewed by 2972 | Submission Open

Keywords: plant; abiotic stress; gene; identification; function

(This special issue belongs to the Section Molecular Plant Sciences)

An Update for Photodynamic Therapy as a Versatile Tool for Biological Breakthroughs

edited by

Leandro M. O. Lourenço

João P. C. Tomé

and

Augusto C. Tomé

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2949 | Submission Open

Keywords: photodynamic theraphy (aPDT); photochemistry; dyes; photosensitizers; porphyrins; phthalocyanines; and other derivatives; reactive oxygen species (ROS); singlet oxygen; cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Heart Diseases: Molecular Pathogenesis, Biomarkers and Therapies

edited by

Nadia Aspromonte

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2945 | Submission Open

Keywords: heart diseases; biomarkers; molecular pathways; personalized medicine; interventional therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 2701-2750 on page 55 of 69.

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