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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cyclodextrin-Based Polymer Systems for Biomedical Applications submission deadline 20 Aug 2025 | 1 articles | Viewed by 3139 | Submission Open
Keywords: cyclodextrins; polymers; grafting; drug delivery; hydrophobic drugs; wound healing; tissue engineering; antimicrobial systems; supramolecular systems
(This special issue belongs to the Section Macromolecules)
Anxiolytic or Antidepressant Activity from Active Principles in Medicinal Plants
edited by Carolina López-Rubalcava and Erika Estrada Camarena
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3075 | Submission Open
Keywords: phytopharmacology; anxiety; depression; medicinal plants; animal models
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Pharmacology of Medicinal Plants
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3057 | Submission Open
Keywords: medicinal plants; drug development; molecular pharmacology; clinical phytopharmacology
(This special issue belongs to the Section Molecular Pharmacology)
Bacteriophage: Molecular Ecology and Pharmacology, 2nd Edition
edited by , and Richard Allen White III
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2999 | Submission Open
Keywords: bacteriophage ecology; bacteriophage pharmacology; intercell communication of bacteria; phage-host interactions; phage-host recognition; phage receptors; phage therapy
(This special issue belongs to the Section Molecular Microbiology)
Big Data in Multi-Omics submission deadline 20 Aug 2025 | 2 articles | Viewed by 2990 | Submission Open
Keywords: data science; big data; omics; data management; data analytics TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in Shona   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate Shona to Simplified Chinese Never translate Shona Never translate admin.mdpi.com
(This special issue belongs to the Section Molecular Informatics)
Signaling Transduction in Health and Disease
edited by and
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2962 | Submission Open
Keywords: signaling pathways; inflammation; human disease; oxidative stress; neurodegeneration; heart disease; antioxidants
(This special issue belongs to the Section Biochemistry)
Cellular and Molecular Mechanisms of Acute Lung Injury submission deadline 20 Aug 2025 | 3 articles | Viewed by 2912 | Submission Open
Keywords: acute lung injury; lung infection; acute respiratory distress syndrom; neutrophil-mediated immune response; alveolar epithelial injury; pulmonary oedema
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Pharmacological Activities of Secondary Metabolites and Derivates of Medicinal Plants Around the World, 2nd Edition
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2862 | Submission Open
Keywords: natural products; secondary metabolites; medicinal chemistry; worldwide traditional medicine; isolation and identification of secondary metabolites; experimental studies; photochemistry; pharmacognosy; medicinal plants
(This special issue belongs to the Section Molecular Pharmacology)
Advances in Computational Biology: Molecular Dynamics Simulation of Biomolecules submission deadline 20 Aug 2025 | 1 articles | Viewed by 2850 | Submission Open
Keywords: computational biology; molecular dynamics; molecular simulation of rare diseases; computational design of antimicrobials; computational design of antivirals; molecular simulation of cancer-related processes; computational design of anti-cancer molecules; molecular simulation of biotechnology processes
(This special issue belongs to the Section Molecular Informatics)
Genetic and Epigenetic Mechanisms in Growth and Neurodevelopmental Disorders
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2830 | Submission Open
Keywords: growth defects; intellectual disability; epilepsy; autism spectrum disorders; epigenetic variations; copy number variations; next generation sequencing
(This special issue belongs to the Section Molecular Genetics and Genomics)
Synthesis, Characterization and Application of Metal and Metal Oxide Nanomaterials submission deadline 20 Aug 2025 | 2 articles | Viewed by 2813 | Submission Open
Keywords: metal nanoparticles; metal nanoclusters; properties of metal nanostructures; optical sensing and bio-sensing; pollutant sensing; metal oxide-based materials; photocatalysis; decomposition of pollutants by photocatalysis; energy production; conversion; and storage; water treatment
(This special issue belongs to the Section Molecular Nanoscience)
The Role of Extracellular Vesicles in Inflammatory Diseases
edited by Kaushik Das
submission deadline 20 Aug 2025 | 5 articles | Viewed by 2781 | Submission Open
Keywords: extracellular vesicles; inflammation; inflammatory diseases; pathogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Myocardial Disease: Molecular Pathology and Treatments
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2781 | Submission Open
Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy; amyloidosis; myocarditis; sarcoidosis; genetic abnormalities; immune mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advancing Climate Resilience in Horticultural Crops Through Omics Technologies
edited by and
submission deadline 20 Aug 2025 | 3 articles | Viewed by 2776 | Submission Open
Keywords: horticultural crops; climate change; omics technologies; stress responses; abiotic stresses; food security; agricultural sustainability; genomics; transcriptomic; proteomics
(This special issue belongs to the Section Molecular Plant Sciences)
Current Research on Plants as Natural Antioxidants
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2772 | Submission Open
Keywords: plant-derived antioxidant; natural products; polyphenols; oxidative stress
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Inflammatory Bowel Disease: Focus on Molecular Research
edited by David Meriwether and
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2710 | Submission Open
Keywords: inflammatory bowel disease; gut microbiota; genomic sequencing; proteomic; lipidomic; metabolomic; therapy; biomarker; animal and organoid model  
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Characteristics of Microorganisms Colonizing Animals and Alternative Methods of Infection Control in the Light of the “One Health” Concept
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2687 | Submission Open
Keywords: zoonotic pathogens; virulence traits; antimicrobial resistance; molecular environment of resistance genes; whole-genome sequencing; microbiome; probiotics; alternative methods of combating pathogens in animals
(This special issue belongs to the Section Molecular Microbiology)
Natural Products in Obesity: Novel Strategies and Molecular Mechanisms: 2nd Edition
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2654 | Submission Open
Keywords: obesity; inflammation; white adipose tissue; adipogenesis; oxidative stress; metabolic disease; molecular mechanisms
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Targeting Oxidative Stress for Disease: 2nd Edition submission deadline 20 Aug 2025 | 3 articles | Viewed by 2654 | Submission Open
Keywords: oxidants and free radical production; physiological activities of free radicals; detrimental effects of free radicals on human health; ROS and ROS-mediated cellular signaling; pathophysiology of oxidative stress; biomarkers of oxidative stress; chronic degenerative diseases; therapeutic approaches targeting oxidative stress; biochemical/molecular targets of chronic diseases; exogenous antioxidants and human health; flavonoids and redox biology in the pathophysiology of diseases; pro-oxidative role of antioxidants: double-sided sword; prooxidant agents in therapy
(This special issue belongs to the Section Molecular Biology)
Research on Transcriptional Regulation in Reproductive Biology
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2629 | Submission Open
Keywords: reproductive biology; molecular research; transcriptional regulations; signaling pathways; gene expression; cell biology
(This special issue belongs to the Section Molecular Biology)
Dietary Bioactive Components in Inflammatory Bowel Disease, 2nd Edition submission deadline 20 Aug 2025 | 2 articles | Viewed by 2574 | Submission Open
Keywords: IBD; dietary bioactive compounds; molecular mechanisms; health promotion; prevention; antioxidant; anti-inflammatory; nutritional support
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advances in Antibody–Drug Conjugates
edited by Bing Sun
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2564 | Submission Open
Keywords: antibody– drug conjugate (ADC); cancer treatment; non-oncology indications; antibody selection; payload; linker; conjugation chemistry
(This special issue belongs to the Section Molecular Immunology)
Cellular and Molecular Mechanisms in Oxidative Stress-Related Diseases, 4th Edition submission deadline 20 Aug 2025 | 3 articles | Viewed by 2558 | Submission Open
Keywords: molecular targets of oxidative stress in oxidative stress related-diseases; oxidative stress and oxidative stress-related pathologies; cellular response to oxidative stress; oxidative stress and apoptosis in oxidative stress-related diseases; oxidative stress and related cell signaling; cell adaptation to oxidative stress; biomarkers of oxidative stress in disease; beneficial effects of natural or synthetic antioxidants in oxidative stress-related diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advancements in Understanding Protein Misfolding Disorders and Cancer
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2509 | Submission Open
Keywords: protein misfolding; cancer; amyloidosis
(This special issue belongs to the Section Molecular Oncology)
New Perspectives in Steroidomics
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2500 | Submission Open
Keywords: steroidomics; steroids; pathophysiology; physiology; diagnostics; treatment; prediction; prognosis; LC-MS/MS; GC-MS/MS
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Research on Diabetes and Obesity
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2443 | Submission Open
Keywords: obesity; diabetes; hypothalamus; insulin resistance; glucose homeostasis; lipid metabolism; adipose tissue; cardiovascular tissue
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Lipid Metabolism in Human Health and Diseases
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2330 | Submission Open
Keywords: lipids; fatty acids; lipid metabolism; metabolic disorders; cardiovascular diseases; neurodegenerative diseases; cancers
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Bioactive Compounds, Smart Polymers and Functionalised Materials for Drug Delivery
edited by Emilia Szymańska
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2325 | Submission Open
Keywords: drug delivery system; bioactive compound; drug carrier; pharmacological activity; polymer
(This special issue belongs to the Section Materials Science)
Fish Nutrition Program and Epigenetic Regulation
edited by Linghong Miao
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2294 | Submission Open
Keywords: nutrients; nutritional strategies; molecule regulation; growth; immunity; reproduction; stress response; epigenetic modifications
(This special issue belongs to the Section Molecular Genetics and Genomics)
MicroRNAs and Other Non-Coding RNAs as Regulators, Biomarkers, and Therapeutic Targets, 2nd Edition
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2260 | Submission Open
Keywords: non-coding RNAs; microRNA; lncRNA; circRNA; piRNA; biomarker; therapeutic target
(This special issue belongs to the Section Molecular Biology)
Latest Review Papers in Molecular Nanoscience
edited by Andre Lee and
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2210 | Submission Open
Keywords: nanomaterials; nanomedicine; nanoparticles; nanoassemblies; nanotechnology; nanocatalysts; nanocomposites
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Research on Skin Inflammation
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2132 | Submission Open
Keywords: skin inflammation; molecular diagnosis; dermatitis; molecular pathogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Pathogenic Microorganisms, Viruses and Therapeutic Strategies submission deadline 20 Aug 2025 | 1 articles | Viewed by 2112 | Submission Open
Keywords: medicinal chemistry; pathogenic microorganisms; bacteria; fungi; viruses; pathogen; therapeutic
(This special issue belongs to the Section Molecular Microbiology)
Oral Squamous Cell Carcinoma: Insights into Molecular Pathways and Emerging Therapeutic Approaches
edited by
submission deadline 20 Aug 2025 | 3 articles | Viewed by 2090 | Submission Open
Keywords: oral squamous cell carcinoma; epigenetics; molecular genetics; gene expression targeted therapy; molecular biomarkers
(This special issue belongs to the Section Molecular Oncology)
Materials for Bioengineering and Biotechnology 2.0 submission deadline 20 Aug 2025 | 1 articles | Viewed by 2084 | Submission Open
Keywords: biomaterials; nanomaterials; nanocarriers; extracellular vesicles; intercellular communication; tissue engineering; scaffolds
(This special issue belongs to the Section Materials Science)
Endothelial Dysfunction and Its Related Cardiometabolic Disorders: From Mechanisms to Targeted Therapies
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2020 | Submission Open
Keywords: endothelial dysfunction; endothelial activation; endothelial nitric oxide synthase; cardiometabolic disease; vascular inflammation; chemokines; adipocytokines; atherosclerosis; diabetes; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advancements in Perovskite and Tandem Solar Cell Technologies
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2012 | Submission Open
Keywords: perovskite solar cells; tandem photovoltaics; charge transporting materials; interfacial engineering; optoelectronic properties
(This special issue belongs to the Section Materials Science)
Biological Research of Rhythms in the Nervous System
edited by Bernát Kocsis and Andreas Draguhn
submission deadline 20 Aug 2025 | 2 articles | Viewed by 1981 | Submission Open
Keywords: mechanisms of rhythmic synchronization; rhythmic firing; neural network oscillations; rhythmic components in EEG; oscillopathy; theta and gamma rhythm; sleep spindle; rhythmic activity and cognition; pathology of rhythmic synchronization in the nervous system; altered rhythmic activity in neuropsychiatric disorders
(This special issue belongs to the Section Molecular Neurobiology)
The Role of the IGF Axis in Disease, 4th Edition
edited by Claire M. Perks
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1951 | Submission Open
Keywords: IGF axis; cancer; obesity; hallmarks of cancer
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advances in Pro-Inflammatory and Anti-Inflammatory Cytokines
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1941 | Submission Open
Keywords: pro-inflammation cytokine; anti-inflammation cytokine; chemotherapy; radiotherapy; signal transduction; microbiome– host response; sepsis; bone marrow; GI; brain
(This special issue belongs to the Section Molecular Immunology)
Retinal Diseases: From Molecular Pathology to Therapies—2nd Edition
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 1939 | Submission Open
Keywords: diabetic retinopathy; age-related macular degeneration; neuroprotection; retina; diabetic macular edema; therapy development; pathophysiology; retinitis pigmentosa; aging; eye trauma; vitreous; macula; choroideremia; stargardt disease; cone– rod dystrophy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Understanding of Allergen Exposome submission deadline 20 Aug 2025 | 2 articles | Viewed by 1933 | Submission Open
Keywords: allergen exposome; profile allergen exposures; climatic change; airborne allergens; molecular triggers; microbial allergens
(This special issue belongs to the Section Molecular Immunology)
Recent Advances in Biomedical Application of Polymeric Micelles submission deadline 20 Aug 2025 | 1 articles | Viewed by 1928 | Submission Open
Keywords: polymeric micelles; nanomedicine; drug delivery; amphiphilic compounds; therapeutic applications
(This special issue belongs to the Section Macromolecules)
New Molecular Perspectives in Crustacean Neuroendocrinology
edited by
submission deadline 20 Aug 2025 | 3 articles | Viewed by 1910 | Submission Open
Keywords: neuroendocrinology; neuropeptides; functional genomics; arthropods development and reproduction; crustacean aquaculture
(This special issue belongs to the Section Molecular Biology)
Molecular Research of Ocular Pathologies, 2nd Edition submission deadline 20 Aug 2025 | 1 articles | Viewed by 1812 | Submission Open
Keywords: ocular pathologies; dry eye; glaucoma; retinal diseases; oxidative stress; inflammation; molecular treatments; molecular biomarkers  
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Redox Enzymes of Bacteria and Parasites as Potential Drug Targets submission deadline 20 Aug 2025 | 1 articles | Viewed by 1801 | Submission Open
Keywords: bacteria and parasite electron transport chains; membrane and cell wall component synthesis; dioxygenases; nitroreductases; antibacterial and antiparasitic agents
(This special issue belongs to the Section Biochemistry)
New Advances in Neuroscience: Molecular Biological Insights
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1777 | Submission Open
Keywords: neurodegenerative diseases; neurodevelopmental disorders; neurohiv; drug abuse; neuropharmacology; epigenetics; exosomes; inflammasomes; biomarkers; gene therapy; stem cell therapy; deep brain stimulation; Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease; autism spectrum disorder; ADHD; dyslexia; neuroinflammation
(This special issue belongs to the Section Molecular Neurobiology)
Design, Synthesis and Applications of the Task-Specific Molecules
edited by and
submission deadline 20 Aug 2025 | 2 articles | Viewed by 1762 | Submission Open
Keywords: task-specific molecules; molecular design and synthesis; physical/chemical absorption; catalysis (including electrocatalysis; photocatalysis; etc.); mechanism on the molecular level; molecular dynamic simulations; optical materials; optoelectronic devices; photoelectric detection; semiconductors
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
New Insights into the Immunopathology of Autoimmune and Drug Induced Liver Injury
edited by Eleni Geladari
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1759 | Submission Open
Keywords: liver disease; liver injury; immune system; immune dysregulation
(This special issue belongs to the Section Molecular Immunology)
Advanced Research on CAR-T Cell Therapy
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1740 | Submission Open
Keywords: CAR T cell therapy; T cell activation; memory lymphocyte differentiation; cancer vaccine; antigen spread
(This special issue belongs to the Section Molecular Immunology)
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