Emerging Roles of Phytochemicals in Cancer Chemoprevention and Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 15
Special Issue Editor
Interests: cancer metabolism; tumor microenvironment; immuno-oncology; therapeutic resistance; natural products; phytomedicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer continues to represent a major global health challenge, with resistance to conventional therapies and severe toxicity limiting the effectiveness of current therapeutic strategies. In recent decades, scientific interest has increasingly shifted toward natural products as a source of novel anticancer agents. Phytochemicals—including flavonoids, alkaloids, polyphenols, and terpenoids—have demonstrated remarkable potential in targeting cancer cells. Understanding the complex interactions between these bioactive compounds and cellular signaling networks is crucial for translating traditional knowledge into modern clinical applications.
This Special Issue aims to provide a comprehensive platform for research focused on the emerging roles of phytochemicals in cancer chemoprevention and treatment. We welcome original research articles and reviews. Research areas may include (but are not limited to) the following:
- The role of natural products in modulating cancer cell signaling pathways;
- Phytochemicals as chemosensitizers to overcome multidrug resistance in standard chemotherapy;
- The impact of phytochemicals on the tumor microenvironment and immune evasion;
- Novel drug delivery systems to enhance the bioavailability and efficacy of phytochemicals;
- Preclinical and clinical studies evaluating the safety and efficacy of plant-derived agents.
Dr. Jaemoo Chun
Guest Editor
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Keywords
- natural products
- phytochemicals
- cancer
- chemoprevention
- cancer therapy
- molecular mechanisms
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