Synthesis and Activity of Natural Products and Analogues
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 679
Editor
Special Issue Information
Dear Colleagues,
Natural products are a key source of bioactive compounds for both medicine and nutrition. Their structural diversity provides inspiration for new drugs and functional foods. Recent advances in synthesis and discovery of target compound or its derivatives using a big database such as GNPS or COCONUT now allow efficient access to complex natural scaffolds and the creation of analogues with improved stability, bioavailability, and activity. In addition to large databases, advanced mass spectrometry software such as MZmine or MS-DIAL, MassQL further accelerates the analysis of bioactive compounds in complex matrices. This Special Issue, “Synthesis and Activity of Natural Products and Analogues”, highlights recent progress in this field.
The Special Issue covers diverse classes of natural products, including alkaloids, flavonoids, terpenoids, and polyketides. Furthermore, it highlights applications not only in treating cancer, inflammation, and infections but also in enhancing antioxidant defense, metabolic regulation, and gut health through functional foods. Collectively, these contributions demonstrate how chemical innovation and biological evaluation continue to expand the impact of natural products.
Dr. Jin-pyo An
Guest Editor
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Keywords
- natural products
- functional food
- synthesis
- high-resolution mass spectrometry
- bioactive compound
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