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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diabetic Retinopathy—Innovation in Diagnosis and Treatment

edited by

Peter Koulen

submission deadline 30 Jul 2025 | Viewed by 431 | Submission Open

Keywords: diabetes mellitus; diabetic macular edema; diagnostics; drug development; neovascularization; neurodegeneration; neuroprotection; retina; therapeutics; vascular disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Crop Stress Biology and Molecular Breeding: 5th Edition

edited by

Youxiong Que

submission deadline 30 Jul 2025 | 1 articles | Viewed by 427 | Submission Open

Keywords: biotic and abiotic stress; variety improvement; crop stress biology; molecular breeding; biological basis; signal transduction pathway; agronomic traits; excellent germplasm

(This special issue belongs to the Section Molecular Plant Sciences)

Cirrhosis: From Molecular Mechanisms to Therapeutic Strategies

edited by

Hongqun Liu

submission deadline 30 Jul 2025 | 1 articles | Viewed by 378 | Submission Open

Keywords: liver; fibrogenesis; cirrhosis; portal hypertension; complications; molecular mechanisms; pathway; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Applications of Gold Nanoparticles in Cancer Theranostics

edited by John Chetley Ford and

Junwei Shi

submission deadline 30 Jul 2025 | Viewed by 358 | Submission Open

Keywords: gold nanoparticles (AuNPs); multifunctional nanoplatform; targeted cancer therapy; drug delivery; theranostics

(This special issue belongs to the Section Materials Science)

Osteoimmunology: Interactions of the Bone and Immune System

edited by

Galliera Emanuela Rita

submission deadline 30 Jul 2025 | Viewed by 326 | Submission Open

Keywords: osteoimmunology markers; bone infection; inflammation and bone; immune response and bone; diagnostic and prognostic markers; bone remodeling; osteoclasts; immune-mediated bone diseases; bone– immune interface

(This special issue belongs to the Section Molecular Immunology)

Molecular Dynamics Simulations of Protein Structures

edited by Alfonso Trezza

submission deadline 30 Jul 2025 | 1 articles | Viewed by 323 | Submission Open

Keywords: molecular dynamics simulations; protein structure analysis; computational methods in structural biology; bioinformatics and drug discovery; protein– ligand interactions

(This special issue belongs to the Section Molecular Biophysics)

Neurological Disorders: From Molecular Mechanisms to Nanomedicine

edited by

Aruna Sharma

submission deadline 30 Jul 2025 | Viewed by 314 | Submission Open

Keywords: stroke; brain and spinal cord trauma; Alzheimer’ s disease; Parkinson’ s disease; nanodrug formulation; stem cells; neuroprotection

(This special issue belongs to the Section Molecular Neurobiology)

Sepsis and Septic Shock: From Molecular Mechanisms to Novel Therapies—2nd Edition

edited by

Markus A. Weigand

and Michael Adamzik

submission deadline 30 Jul 2025 | Viewed by 308 | Submission Open

Keywords: sepsis; septic shock; mechanistic insight; epigenetics; immunometabolism; biomarkers; therapy approach; stratification; precision diagnostics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Autoimmune Diseases: From Pathogenesis to Treatment and Prognostic Markers

edited by Alessandra Bettiol

submission deadline 30 Jul 2025 | Viewed by 276 | Submission Open

Keywords: autoimmune diseases; inflammation; immunity; pathogenesis; immunosuppressants; biologics; biomarkers

(This special issue belongs to the Section Molecular Immunology)

Macro- and Micronutrients in Health and Diseases

edited by

Karolina Orywal

and Mariusz Gryko

submission deadline 30 Jul 2025 | 1 articles | Viewed by 253 | Submission Open

Keywords: macronutrients; micronutrients; vitamins; macrominerals; trace elements; cancer; obesity; cardiovascular diseases; diabetes; osteoporosis; immune disorders; neurodegenerative diseases

(This special issue belongs to the Section Molecular Biology)

Molecular Biology and Diagnosis on Biliary and Pancreatic Cancers

edited by Francesco Vasuri and Luca Saragoni

submission deadline 30 Jul 2025 | Viewed by 233 | Submission Open

Keywords: biliary cancer; pancreatic cancer; histological diagnoses; cytological diagnoses; chromosome aneuploidy; specific genetic mutations

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms Linking Obesity to Atherosclerosis Pathogenesis

edited by

Weibin Shi

submission deadline 30 Jul 2025 | 1 articles | Viewed by 224 | Submission Open

Keywords: obesity; overweight; atherosclerosis; coronary artery disease; obesity paradox; body mass index; visceral fat

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Obesity: From Pathogenesis to Therapeutic Targets

edited by Omar Al Massadi, Mar Quiñones and

Luisa Maria Seoane

submission deadline 30 Jul 2025 | Viewed by 214 | Submission Open

Keywords: obesity; energy balance; type 2 diabetes; liver disease; adipose tissue; brain

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms in Kidney Disease

edited by

Tzong-Shyuan Lee

submission deadline 30 Jul 2025 | Viewed by 189 | Submission Open

Keywords: kidney disease; inflammation; redox; senescence; cell death; fibrosis; signaling pathway; uremic syndrome; cardiorenal syndrome; gut– kidney axis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Parkinson’s Disease and Related Diseases: Mechanisms, Genetic Factors and Treatments

edited by

Stergios Boussios

submission deadline 30 Jul 2025 | Viewed by 155 | Submission Open

Keywords: Parkinson’ s disease; neurodegenerative disorders; α -synuclein aggregation; neuroinflammation; gene therapy; biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Circulating Non-Coding RNAs as Diagnostic and Prognostic Markers of Human Diseases: 3rd Edition

edited by

Kyriacos N. Felekkis

and

Christos Papaneophytou

submission deadline 30 Jul 2025 | Viewed by 149 | Submission Open

Keywords: miRNA; gene expression regulation; diagnosis; prognosis; therapy; biomarkers

(This special issue belongs to the Section Biochemistry)

Artificial Intelligence in Nano- and Bio-Technology Systems: Focus on Molecular Research

edited by

Abbas Amini

submission deadline 30 Jul 2025 | Viewed by 145 | Submission Open

Keywords: artificial intelligence; nanotechnology; biotechnology; medicine; energy systems; blockchain

(This special issue belongs to the Section Molecular Nanoscience)

Protein Design and Engineering in Biochemistry

edited by Om Prakash Narayan

submission deadline 30 Jul 2025 | Viewed by 142 | Submission Open

Keywords: protein engineering; molecular biology; biochemical tools; computational protein design; directed evolution; CRISPR/Cas9; synthetic biology; biomaterials; protein therapeutics; regenerative medicine

(This special issue belongs to the Section Molecular Biology)

Cerebrovascular Diseases: Mediators of the Capillary No-Reflow Phenomenon After Acute Ischemic Stroke

edited by Ákos Menyhárt

submission deadline 30 Jul 2025 | Viewed by 134 | Submission Open

Keywords: capillary; acute ischemic stroke; cerebrovascular; no-reflow

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Bioactive Compounds in Human Health and Disease: 3rd Edition

edited by

Guan-Jhong Huang

submission deadline 30 Jul 2025 | Viewed by 132 | Submission Open

Keywords: cancer; inflammation; cardiovascular diseases; plants; bioactive compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Green Chemical Pesticide Design, Synthesis and Evaluation

edited by Ranfeng Sun

submission deadline 30 Jul 2025 | Viewed by 123 | Submission Open

Keywords: green pesticides; natural products; action mechanism of pesticides; synthesis

(This special issue belongs to the Section Biochemistry)

Research Progress and Therapeutic Targets of Chronic Kidney Disease

edited by

Stefanos Roumeliotis

submission deadline 30 Jul 2025 | Viewed by 122 | Submission Open

Keywords: blood pressure; cardiovascular disease; chronic kidney disease; diabetes; hypertension; inflammation; oxidative stress; sodium glucose transporter-2; vascular calcification

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Elucidating How Chondrocytes Maintain Cartilage Stability

edited by James A. Martin

submission deadline 30 Jul 2025 | Viewed by 121 | Submission Open

Keywords: chondrocytes; articular cartilage; chondrogenesis; osteoarthritis; mechano-transduction; aging; extracellular matrix

(This special issue belongs to the Section Molecular Biology)

The Brain’s Regeneration Potential: The Role of Neural Progenitor Cells in Neuropsychiatric Therapy

edited by

Beatriz Caballero

and

Yaiza Potes

submission deadline 30 Jul 2025 | Viewed by 118 | Submission Open

Keywords: neural stem cells; neural progenitor cells; neuropsychiatric disorders; neurodegeneration; neurogenesis; neuroplasticity; melatonin; psychoactive drugs

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Forensics at Trial

edited by

Guido Viel

submission deadline 30 Jul 2025 | Viewed by 112 | Submission Open

Keywords: forensic science; molecular biology; evidence; proof; justice; trial; forensic pathology; forensic genetics; forensic histology; forensic toxicology

(This special issue belongs to the Section Molecular Toxicology)

Exploring Tolerance Mechanisms in Plants Under Stress

edited by

Lujun Yu

submission deadline 30 Jul 2025 | Viewed by 112 | Submission Open

Keywords: stress; tolerance; gene family; phytohormones; mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Advancing Liver Health: State of the Art and Recent Research Advances

edited by

Chase Wehrle

submission deadline 30 Jul 2025 | Viewed by 111 | Submission Open

Keywords: liver; liver cancer and malignancy; liver transplantation; inflammation and immunity; liver health and ageing; molecular genomics; cellular senescence; metabolic dysfunction-associated liver disease; cirrhosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gene Mining and Germplasm Innovation for the Important Traits in Rice (Second Edition)

edited by

Shimin Zuo

and

Yongmei Bao

submission deadline 30 Jul 2025 | Viewed by 104 | Submission Open

Keywords: rice; gene mining; important traits; molecular design; gene editing; germplasm innovation

(This special issue belongs to the Section Molecular Plant Sciences)

Neurohormones in Cardiac Fibrosis and Heart Failure

edited by

Helmy M. Siragy

submission deadline 30 Jul 2025 | Viewed by 102 | Submission Open

Keywords: heart failure; neurohormones; cardiac fibrosis; angiotensin II; aldosterone; endothelin; catecholamines

(This special issue belongs to the Section Molecular Biology)

New Insights in Antibody Therapy

edited by

Loredana Frasca

submission deadline 30 Jul 2025 | Viewed by 101 | Submission Open

Keywords: biological therapy; antibody therapy; non-communicable diseases; infectious diseases; chronic disease

(This special issue belongs to the Section Molecular Immunology)

Neuroblastoma: Molecular Pathology, Diagnostics and Therapeutics

edited by

Simona Dedoni

submission deadline 30 Jul 2025 | Viewed by 99 | Submission Open

Keywords: neuroblastoma; solid cancer; immature nerve cells; molecular mechanism; biomarker; tumor heterogeneity

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Molecular Research in Brain Tumors

edited by

Shiv K. Gupta

submission deadline 30 Jul 2025 | Viewed by 93 | Submission Open

Keywords: targeted therapy; blood– brain barrier; GBM; glioma; immune checkpoint blockers; TME

(This special issue belongs to the Section Molecular Oncology)

Venoms and Ion Channels (3rd Edition)

edited by

Steve Peigneur

submission deadline 30 Jul 2025 | Viewed by 93 | Submission Open

Keywords: sodium channels; potassium channels; calcium channels; trp channels; acetylcholine receptors; cone snail venom peptides; spider venom peptides; sea anemone toxins; scorpion toxins; snake toxins

(This special issue belongs to the Section Molecular Toxicology)

Molecular Interactions and Advanced Computational Methods for Biomolecular Systems

edited by

Amar Singh

submission deadline 30 Jul 2025 | Viewed by 92 | Submission Open

Keywords: molecular interactions; biological systems; computational biology; protein– protein interactions; protein docking; bioinformatics; structural modeling; multiscale modeling techniques

(This special issue belongs to the Section Molecular Biophysics)

The Roles of Oxidative Stress in Metabolic Syndrome

edited by

Maria Magdalena Quetglas-Llabrés

and

Margalida Monserrat-Mesquida

submission deadline 30 Jul 2025 | Viewed by 91 | Submission Open

Keywords: oxidative stress; metabolic syndrome; inflammation; antioxidants; human chronic diseases; cardiometabolic diseases; nutrition; lifestyle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research in Immune Cell Therapy

edited by

Alexander Huang

submission deadline 30 Jul 2025 | Viewed by 91 | Submission Open

Keywords: molecular biology; bioinformatics; proteomics; molecular mechanisms; genomics

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms Underlying Skin Diseases

edited by Maria Lucia Dell'Anna

submission deadline 30 Jul 2025 | Viewed by 87 | Submission Open

Keywords: pigmentation; lipid signaling; immune cells; inflammation; skin barrier; oxidative damage; mitochondria

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Theranostic Application of Reactive Oxygen Species-Sensitive Nanocarriers

edited by

Young-Il Jeong

submission deadline 30 Jul 2025 | Viewed by 80 | Submission Open

Keywords: ROS generation; ROS detection; ROS-sensitive nanoparticles; Photodynamic therapy (PDT)

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Insights in Biomodelling

edited by

Jacques Demongeot

submission deadline 30 Jul 2025 | Viewed by 79 | Submission Open

Keywords: biomodelling; biomathematics; bioinformatics; biostatistics; biophysics; theoretical biology; theoretical ecology; mathematical biology; theoretical physics; physical chemistry

(This special issue belongs to the Section Molecular Informatics)

Natural Compounds in Cancer: Targeting Immune Cells and Signalling Pathways

edited by

Tomasz Jędrzejewski

submission deadline 30 Jul 2025 | Viewed by 79 | Submission Open

Keywords: natural compounds; cancer; inflammation; signalling pathways; antineoplastic agents; macrophage; T cells; molecular mechanism of pharmacological action; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Advanced Research on Plant-Derived Products in the Service of Immune Regulation

edited by

Lyuba Dineva Miteva

submission deadline 30 Jul 2025 | Viewed by 78 | Submission Open

Keywords: plant bioactive compound; inflammation; immunity; cytokine; chronic disease

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Reproductive Immunology: Pathological Mechanisms, Genetics, and Immunotherapy

edited by

Ming Zhang

submission deadline 30 Jul 2025 | Viewed by 77 | Submission Open

Keywords: genital tract; fertilization; embryo development; fetus development; immune

(This special issue belongs to the Section Molecular Immunology)

Molecular Insights into Environmental Toxicology in Cancer

edited by

Silvia Vivarelli

submission deadline 30 Jul 2025 | Viewed by 71 | Submission Open

Keywords: environmental carcinogenesis; toxic exposure; exposome; occupational cancer risk; biomarkers of exposure; new approach methodologies (NAMs)

(This special issue belongs to the Section Molecular Oncology)

Molecular Research on Gene Editing in Agricultural Crops

edited by

Xiaoli Shi

submission deadline 30 Jul 2025 | Viewed by 67 | Submission Open

Keywords: genome editing; molecular insights; agricultural crops

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms Study of Functional Foods and Nutrients in Human Health Interventions

edited by

Rui Jiao

submission deadline 30 Jul 2025 | Viewed by 66 | Submission Open

Keywords: functional foods; molecular mechanisms; nutrient bioavailability; chronic disease prevention; health interventions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Harnessing Bioinformatics for miRNA Research: Methods, Insights and Applications

edited by Maria Rosaria Tumolo and Saverio Sabina

submission deadline 30 Jul 2025 | Viewed by 65 | Submission Open

Keywords: microRNA; bioinformatics; hub genes; miRNA target prediction; miRNA regulatory networks; miRNA-based biomarkers; artificial intelligence in miRNA research; multi-omics approaches

(This special issue belongs to the Section Molecular Informatics)

Nanomedicine for Diagnostic and Therapeutic Application

edited by

Nicola D'Avanzo

and Antonella Barone

submission deadline 30 Jul 2025 | Viewed by 63 | Submission Open

Keywords: polymeric nanoparticles; lipid nanoparticles; diagnostic; theranostic; targeted drug delivery; nonovesicles; prescion medicine

(This special issue belongs to the Section Molecular Nanoscience)

Drugs—from Chemical Structure to Biological Activity

edited by

Sravani Sana

submission deadline 30 Jul 2025 | Viewed by 63 | Submission Open

Keywords: hit molecule; lead optimization; drug design; virtual screening; molecule descriptors; structure– activity relationship; pharmacokinetic/ADME profile; in vitro biological activity

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Ovarian Cancer Metastasis and Chemotherapy Resistance

edited by

Carmela Ricciardelli

and

Noor A. Lokman

submission deadline 30 Jul 2025 | Viewed by 63 | Submission Open

Keywords: ovarian cancer; metastasis; biomarkers; chemotherapy resistance; tumor microenvironment; peritoneal– cancer cell interactions; proteomics; novel therapeutic targets

(This special issue belongs to the Section Molecular Oncology)

Drugs Targeting Cancer Signaling Pathways: Dissecting Mechanisms to Unlock New Therapeutic Targets

edited by Souleymane Abdoul-Azize

submission deadline 30 Jul 2025 | Viewed by 62 | Submission Open

Keywords: small-molecule drugs; signal transduction; therapeutic targets; therapeutic resistance; oncogenic signaling; novel biomarkers; cancer therapy; cancer signaling pathways; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Displaying special issue 1451-1500 on page 30 of 68.

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